产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲抗体
目录 :
MAB210-100
规格 :
100 ug (also 500 ug, 25 ug)
价格 :
469美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1825
反应物种 :
人类
应用 :
中和反应
更多信息或购买 :
文章摘录数: 16
参考文献
Bhuyan S, Pal B, Pathak L, Saikia P, Mitra S, Gayan S, et al. Targeting hypoxia-induced tumor stemness by activating pathogen-induced stem cell niche defense. Front Immunol. 2022;13:933329 pubmed 出版商
Kim J, Kim J, Park M, Kim S, Kim T, Kim J, et al. NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell function. Exp Mol Med. 2020;52:1298-1309 pubmed 出版商
Sellau J, Groneberg M, Fehling H, Thye T, Hoenow S, Marggraff C, et al. Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1. Nat Commun. 2020;11:3459 pubmed 出版商
Reuschl A, Edwards M, Parker R, Connell D, Hoang L, Halliday A, et al. Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways. PLoS Pathog. 2017;13:e1006577 pubmed 出版商
Uebele J, Stein C, Nguyen M, Schneider A, Kleinert F, Ticha O, et al. Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus. PLoS Pathog. 2017;13:e1006387 pubmed 出版商
Robinet P, Baychelier F, Fontaine T, Picard C, Debre P, Vieillard V, et al. A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cells. J Immunol. 2014;192:5332-42 pubmed 出版商
Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, et al. Activin A as a mediator of NK-dendritic cell functional interactions. J Immunol. 2014;192:1241-8 pubmed 出版商
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, et al. IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol. 2012;10:e1001395 pubmed 出版商
Nicolaidou V, Wong M, Redpath A, Ersek A, Baban D, Williams L, et al. Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation. PLoS ONE. 2012;7:e39871 pubmed 出版商
Navenot J, Fujii N, Peiper S. KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis. Mol Pharmacol. 2009;75:1074-83 pubmed 出版商
Arnold R, Neumann M, König W. Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells. Immunology. 2007;121:71-81 pubmed
van Grevenstein W, Hofland L, van Rossen M, van Koetsveld P, Jeekel J, van Eijck C. Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers. Dig Dis Sci. 2007;52:2775-83 pubmed
Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos G, et al. Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia. Exp Hematol. 2006;34:1312-22 pubmed
Ebert E, Mehta V. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell Immunol. 2006;241:7-13 pubmed
Tay S, McCormack A, Rose M. Effect of cognate human CD4+ T cell and endothelial cell interactions upon chemokine production. Transplantation. 2004;78:987-94 pubmed
Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, et al. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases. J Leukoc Biol. 2001;70:617-23 pubmed
图像
图像 1 :
安迪生物R&D MAB210-100 图像 1
Cytotoxicity Induced by TNF-a and Neutralization by Human TNF-a Antibody.
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB210
SKU号 :
MAB210-100
产品名称 :
肿瘤坏死因子甲抗体
描述 :
The Human TNF-alpha Antibody from R&D Systems is a mouse monoclonal antibody to TNF-alpha. This antibody reacts with human. The Human TNF-alpha Antibody has been validated for the following applications: Neutralization.
靶标 :
肿瘤坏死因子甲
类别 :
一抗
单位尺寸 :
100 ug (also 500 ug, 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
1825
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
E. coli -derived recombinant human TNF-alpha , Gly57-Leu233, Accession # P01375
抗体亚型 :
IgG1
纯度 :
蛋白质A或G纯化来自腹水
物种 :
人类
特异性 :
Detects human TNF-alpha in direct ELISAs. In direct ELISAs, approximately 50% cross-reactivity with recombinant rhesus macaque TNF-alpha is observed and no cross-reactivity with recombinant cotton rat, mouse, rat, or porcine TNF-alpha is observed. It shows no cross-reactivity with recombinant human (rh) APRIL, rhBAFF, rhEDA-A2, rhFas Ligand, rhGITR Ligand, rhLIGHT, rhOX40 Ligand, rhRANK Ligand, rhTNF-beta , rhTRAIL, rhTRANCE, rhTWEAK, or rhVEGI.
基因符号 :
肿瘤坏死因子
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P01375
应用 :
中和反应
美元 :
469美元
别名 :
APC1 protein, Cachectin, Cachetin, DIF, TNF, TNF, monocyte-derived, TNF-a, TNFA, TNFalpha, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFG1F, TNFSF1A, TNFSF2, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.