产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
LDLR抗体
目录 :
MAB2148-100
规格 :
100 ug (also 500 ug, 25 ug)
价格 :
489美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
472413
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫沉淀, 流式细胞仪
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 9
参考文献
Clark L, Clark S, Lin C, Liu J, Coscia A, Nabel K, et al. VLDLR and ApoER2 are receptors for multiple alphaviruses. Nature. 2021;: pubmed 出版商
Masuda Y, Yamaguchi S, Suzuki C, Aburatani T, Nagano Y, Miyauchi R, et al. Generation and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain-Fused Anticalin Protein. J Pharmacol Exp Ther. 2018;365:368-378 pubmed 出版商
Susan Resiga D, Girard E, Kiss R, Essalmani R, Hamelin J, Asselin M, et al. The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA. J Biol Chem. 2017;292:1573-1590 pubmed 出版商
Weider E, Susan Resiga D, Essalmani R, Hamelin J, Asselin M, Nimesh S, et al. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation. J Biol Chem. 2016;291:16659-71 pubmed 出版商
Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed 出版商
Amirache F, Levy C, Costa C, Mangeot P, Torbett B, Wang C, et al. Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor. Blood. 2014;123:1422-4 pubmed 出版商
Karta M, Wickert L, Curran C, Gavala M, Denlinger L, Gern J, et al. Allergen challenge in vivo alters rhinovirus-induced chemokine secretion from human airway macrophages. J Allergy Clin Immunol. 2014;133:1227-1230.e4 pubmed 出版商
DeVay R, Shelton D, Liang H. Characterization of proprotein convertase subtilisin/kexin type 9 (PCSK9) trafficking reveals a novel lysosomal targeting mechanism via amyloid precursor-like protein 2 (APLP2). J Biol Chem. 2013;288:10805-18 pubmed 出版商
Poirier S, Mayer G, Poupon V, McPherson P, Desjardins R, Ly K, et al. Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route. J Biol Chem. 2009;284:28856-64 pubmed 出版商
图像
图像 1 :
安迪生物R&D MAB2148-100 图像 1
Detection of LDL R antibody in HepG2 Human Cell Line antibody by Flow Cytometry.
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB2148
SKU号 :
MAB2148-100
产品名称 :
LDLR抗体
描述 :
The Human LDLR Antibody from R&D Systems is a mouse monoclonal antibody to LDLR. This antibody reacts with human. The Human LDLR Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunoprecipitation, CyTOF-ready, ELISA Capture (Matched Antibody Pair).
靶标 :
LDLR
类别 :
一抗
单位尺寸 :
100 ug (also 500 ug, 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
472413
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Chinese hamster ovary cell line CHO-derived recombinant human LDLR, Ala22-Arg788, Accession # P01130
抗体亚型 :
IgG1
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects human LDLR in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) LDLR, recombinant human LRP-5, or rmLRP-6 is observed.
基因符号 :
LDLR
accessionNumbers :
P01130
应用 :
Western Blot, Flow Cytometry, Immunoprecipitation, CyTOF-ready, ELISA Capture (Matched Antibody Pair)
美元 :
489美元
别名 :
FH, FHC, LDL R, LDL receptor, LDLCQ2, low density lipoprotein receptor, low-density lipoprotein receptor, low-density lipoprotein receptor class A domain-containing protein 3
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.