产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
小鼠趋化因子受体4抗体
目录 :
MAB21651
规格 :
100 ug (also 25 ug, 500 ug)
价格 :
369美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
247506
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫细胞化学, 中和反应, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 28
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:50; 图 1b, 1e, 2b, 2e
Lopez M, Seyed Razavi Y, Jamali A, Harris D, Hamrah P. The Chemokine Receptor CXCR4 Mediates Recruitment of CD11c+ Conventional Dendritic Cells Into the Inflamed Murine Cornea. Invest Ophthalmol Vis Sci. 2018;59:5671-5681 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 6a
Cho K, Yoon D, Qiu S, Danziger Z, Grill W, Wetsel W, et al. Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes. Dis Model Mech. 2017;10:559-579 pubmed 出版商
Kalpana G, Figy C, Yeung M, Yeung K. Reduced RhoA expression enhances breast cancer metastasis with a concomitant increase in CCR5 and CXCR4 chemokines signaling. Sci Rep. 2019;9:16351 pubmed 出版商
Capitano M, Mor Vaknin N, Saha A, Cooper S, Legendre M, Guo H, et al. Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling. J Clin Invest. 2019;129:2555-2570 pubmed 出版商
Nagashima H, Shinoda M, Honda K, Kamio N, Hasuike A, Sugano N, et al. CXCR4 signaling contributes to alveolar bone resorption in Porphyromonas gingivalis-induced periodontitis in mice. J Oral Sci. 2017;: pubmed 出版商
Zhang M, Qiu L, Zhang Y, Xu D, Zheng J, Jiang L. CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells. Sci Rep. 2017;7:8289 pubmed 出版商
Saha A, Ahn S, Blando J, Su F, Kolonin M, DiGiovanni J. Proinflammatory CXCL12-CXCR4/CXCR7 Signaling Axis Drives Myc-Induced Prostate Cancer in Obese Mice. Cancer Res. 2017;77:5158-5168 pubmed 出版商
Nagashima H, Shinoda M, Honda K, Kamio N, Watanabe M, Suzuki T, et al. CXCR4 signaling in macrophages contributes to periodontal mechanical hypersensitivity in Porphyromonas gingivalis-induced periodontitis in mice. Mol Pain. 2017;13:1744806916689269 pubmed 出版商
Smith N, Pietrancosta N, Davidson S, Dutrieux J, Chauveau L, Cutolo P, et al. Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement. Nat Commun. 2017;8:14253 pubmed 出版商
Moshfegh C, Aires L, Kisielow M, Vogel V. A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways. Sci Rep. 2016;6:25104 pubmed 出版商
Chen Q, Zhang M, Li Y, Xu D, Wang Y, Song A, et al. CXCR7 Mediates Neural Progenitor Cells Migration to CXCL12 Independent of CXCR4. Stem Cells. 2015;33:2574-85 pubmed 出版商
Spada R, Rojas J, Pérez Yagüe S, Mulens V, Cannata Ortiz P, Bragado R, et al. NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery. J Leukoc Biol. 2015;97:583-98 pubmed 出版商
Butschkau A, Wagner N, Genz B, Vollmar B. Protein z exerts pro-angiogenic effects and upregulates CXCR4. PLoS ONE. 2014;9:e113554 pubmed 出版商
Deniro M, Al Mohanna F. Nuclear factor kappa-B signaling is integral to ocular neovascularization in ischemia-independent microenvironment. PLoS ONE. 2014;9:e101602 pubmed 出版商
Zgraggen S, Huggenberger R, Kerl K, Detmar M. An important role of the SDF-1/CXCR4 axis in chronic skin inflammation. PLoS ONE. 2014;9:e93665 pubmed 出版商
Roy L, Sahraei M, Schettini J, Gruber H, Besmer D, Mukherjee P. Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches. BMC Cancer. 2014;14:225 pubmed 出版商
Kavanagh D, Yemm A, Zhao Y, Frampton J, Kalia N. Mechanisms of adhesion and subsequent actions of a haematopoietic stem cell line, HPC-7, in the injured murine intestinal microcirculation in vivo. PLoS ONE. 2013;8:e59150 pubmed 出版商
Yang Q, Kim D, Kaucher A, Oatley M, Oatley J. CXCL12-CXCR4 signaling is required for the maintenance of mouse spermatogonial stem cells. J Cell Sci. 2013;126:1009-20 pubmed 出版商
Köhler T, Reizis B, Johnson R, Weighardt H, Forster I. Influence of hypoxia-inducible factor 1? on dendritic cell differentiation and migration. Eur J Immunol. 2012;42:1226-36 pubmed 出版商
Liu H, Liu S, Li Y, Wang X, Xue W, Ge G, et al. The role of SDF-1-CXCR4/CXCR7 axis in the therapeutic effects of hypoxia-preconditioned mesenchymal stem cells for renal ischemia/reperfusion injury. PLoS ONE. 2012;7:e34608 pubmed 出版商
Salvucci O, Jiang K, Gasperini P, Maric D, Zhu J, Sakakibara S, et al. MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1. Haematologica. 2012;97:818-26 pubmed 出版商
Rider P, Carmi Y, Guttman O, Braiman A, Cohen I, Voronov E, et al. IL-1? and IL-1? recruit different myeloid cells and promote different stages of sterile inflammation. J Immunol. 2011;187:4835-43 pubmed 出版商
Liu H, Xue W, Ge G, Luo X, Li Y, Xiang H, et al. Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1? in MSCs. Biochem Biophys Res Commun. 2010;401:509-15 pubmed 出版商
Strasser G, Kaminker J, Tessier Lavigne M. Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching. Blood. 2010;115:5102-10 pubmed 出版商
Sengupta N, Afzal A, Caballero S, Chang K, Shaw L, Pang J, et al. Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization. Invest Ophthalmol Vis Sci. 2010;51:2697-704 pubmed 出版商
Schroeter M, Humboldt T, Schafer K, Konstantinides S. Rosuvastatin reduces atherosclerotic lesions and promotes progenitor cell mobilisation and recruitment in apolipoprotein E knockout mice. Atherosclerosis. 2009;205:63-73 pubmed 出版商
Feng W, McCabe N, Mahabeleshwar G, Somanath P, Phillips D, Byzova T. The angiogenic response is dictated by beta3 integrin on bone marrow-derived cells. J Cell Biol. 2008;183:1145-57 pubmed 出版商
Williams C, Segarra M, Sierra M, Sainson R, Tosato G, Harris A. Regulation of CXCR4 by the Notch ligand delta-like 4 in endothelial cells. Cancer Res. 2008;68:1889-95 pubmed 出版商
产品信息
品牌 :
R&D Systems
master code :
MAB21651
SKU号 :
MAB21651-100
产品名称 :
小鼠趋化因子受体4抗体
描述 :
The Mouse CXCR4 Antibody from R&D Systems is a rat monoclonal antibody to CXCR4. This antibody reacts with mouse. The Mouse CXCR4 Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-ready.
靶标 :
趋化因子受体4
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug, 500 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
247506
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
大鼠
免疫原 :
Y3 rat myeloid cell line transfected with mouse CXCR4, Met1-Ser359, Accession # P70658
抗体亚型 :
IgG2b
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
小鼠
特异性 :
Detects mouse CXCR4 transfectants. Does not stain irrelevant transfectants.
基因符号 :
趋化因子受体4
功能细节 :
ActivityAssaywCitation not found None None None None
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB21651
accessionNumbers :
P70658
应用 :
Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-ready
2020美元 :
339
2021美元 :
369美元
别名 :
CD184, chemokine (C-X-C motif) receptor 4, chemokine (C-X-C motif), receptor 4 (fusin), C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, D2S201E, D2S201ESDF-1 receptor, FB22, Fusin, HM89, HM89NPYRL, HSY3RR, LAP3, LAP-3, LCR1, LESTR, LESTRCD184 antigen, Leukocyte-derived seven transmembrane domain receptor, leukocyte-derived seven-transmembrane-domain receptor, lipopolysaccharide-associated protein 3, neuropeptide Y receptor Y3, NPY3R, NPY3RWHIM, NPYR, NPYRL, NPYY3R, pCXCR4, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, Stromal cell-derived factor 1 receptor, WHIMS
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.