产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
人类IL-10抗体
目录 :
MAB217
规格 :
100 ug (also 25 ug, 500 ug)
价格 :
369美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
23738
反应物种 :
人类
应用 :
免疫印迹, 中和反应
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 20
参考文献
Brekke K, Sommerfelt M, Okvist M, Dyrhol Riise A, Kvale D. The therapeutic HIV Env C5/gp41 vaccine candidate Vacc-C5 induces specific T cell regulation in a phase I/II clinical study. BMC Infect Dis. 2017;17:228 pubmed 出版商
Hock B, MacPherson S, McKenzie J. Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells. PLoS ONE. 2017;12:e0172858 pubmed 出版商
Huynh L, Kusnadi A, Park S, Murata K, Park Min K, Ivashkiv L. Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages. Sci Rep. 2016;6:31959 pubmed 出版商
Heine G, Drozdenko G, Grün J, Chang H, Radbruch A, Worm M. Autocrine IL-10 promotes human B-cell differentiation into IgM- or IgG-secreting plasmablasts. Eur J Immunol. 2014;44:1615-21 pubmed 出版商
Herath S, Benlahrech A, Papagatsias T, Athanasopoulos T, Bouzeboudjen Z, Hervouet C, et al. Fusion of ubiquitin to HIV gag impairs human monocyte-derived dendritic cell maturation and reduces ability to induce gag T cell responses. PLoS ONE. 2014;9:e88327 pubmed 出版商
Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, et al. TNF-? blockade induces IL-10 expression in human CD4+ T cells. Nat Commun. 2014;5:3199 pubmed 出版商
Gruber S, Gloria Luciani M, Grundtner P, Zdanov A, Gasche C. Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1. Eur J Immunol. 2008;38:3365-75 pubmed 出版商
Alatrakchi N, Graham C, van der Vliet H, Sherman K, Exley M, Koziel M. Hepatitis C virus (HCV)-specific CD8+ cells produce transforming growth factor beta that can suppress HCV-specific T-cell responses. J Virol. 2007;81:5882-92 pubmed
Bayry J, Triebel F, Kaveri S, Tough D. Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J Immunol. 2007;178:4184-93 pubmed
Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed
Fischer J, West J, Agochukwu N, Suire C, Hale Donze H. Induction of host chemotactic response by Encephalitozoon spp. Infect Immun. 2007;75:1619-25 pubmed
Iliopoulou E, Karamouzis M, Missitzis I, Ardavanis A, Sotiriadou N, Baxevanis C, et al. Increased frequency of CD4+ cells expressing CD161 in cancer patients. Clin Cancer Res. 2006;12:6901-9 pubmed
Ebert E, Mehta V. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell Immunol. 2006;241:7-13 pubmed
Godfrey W, Spoden D, Ge Y, Baker S, Liu B, Levine B, et al. Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood. 2005;105:750-8 pubmed
Phillips T. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis. Electrophoresis. 2004;25:1652-9 pubmed
Perrier P, Martinez F, Locati M, Bianchi G, Nebuloni M, Vago G, et al. Distinct transcriptional programs activated by interleukin-10 with or without lipopolysaccharide in dendritic cells: induction of the B cell-activating chemokine, CXC chemokine ligand 13. J Immunol. 2004;172:7031-42 pubmed
Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, et al. Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells. Immunology. 2004;112:274-89 pubmed
Godfrey W, Ge Y, Spoden D, Levine B, June C, Blazar B, et al. In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures. Blood. 2004;104:453-61 pubmed
Koenen H, Fasse E, Joosten I. IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression. J Immunol. 2003;171:6431-41 pubmed
Corinti S, Albanesi C, la Sala A, Pastore S, Girolomoni G. Regulatory activity of autocrine IL-10 on dendritic cell functions. J Immunol. 2001;166:4312-8 pubmed
产品信息
品牌 :
R&D Systems
master code :
MAB217
SKU号 :
MAB217-100
产品名称 :
人类IL-10抗体
描述 :
The Human IL-10 Antibody from R&D Systems is a mouse monoclonal antibody to IL-10. This antibody reacts with human. The Human IL-10 Antibody has been validated for the following applications: Western Blot, Simple Western, Neutralization.
靶标 :
IL-10
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug, 500 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
23738
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
E. coli -derived recombinant human IL-10, Ser19-Asn178, Accession # P22301
抗体亚型 :
IgG2b
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects human IL-10 in Western blots. In Western blots, this antibody shows approximately 5% cross-reactivity with recombinant mouse IL-10.
基因符号 :
白细胞介素10
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB217
accessionNumbers :
P22301
应用 :
Western Blot, Simple Western, Neutralization
2020美元 :
339
2021美元 :
369美元
别名 :
CSIF, CSIFMGC126450, 细胞因子合成抑制因子, GVHDS, 白细胞介素10, IL10A, IL-10 MGC126451, 白细胞介素10, 白细胞介素10, TGIF
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.