IL-12 p70抗体 | 安迪生物R&D MAB219-100 产品信息

产品简要

公司名称 :

安迪生物R&D

产品类型 :

抗体

产品名称 :

IL-12 p70抗体

MAB219-100

规格 :

100 ug (also 25 ug, 500 ug)

价格 :

453美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

24910

反应物种 :

人类

应用 :

免疫印迹, 免疫组化, 中和反应, 流式细胞仪

更多信息或购买 :

安迪生物R&D 产品网页

文章摘录数: 24

出版应用/物种/样本/稀释	参考文献
流式细胞仪; 人类; 图 2c	Webb L, Fra Bido S, Innocentin S, Matheson L, Attaf N, Bignon A, et al. Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ. Aging Cell. 2021;20:e13295 pubmed 出版商
	Wellemans V, Benhassou H, Fuselier E, Bellesort F, Dury S, Lebargy F, et al. Role of CCR3 in respiratory syncytial virus infection of airway epithelial cells. iScience. 2021;24:103433 pubmed 出版商
	Serrano R, Coch C, Peters C, Hartmann G, Wesch D, Kabelitz D. Monocyte-dependent co-stimulation of cytokine induction in human γδ T cells by TLR8 RNA ligands. Sci Rep. 2021;11:15231 pubmed 出版商
	Maura D, Elmekki N, Goddard C. The ammonia oxidizing bacterium Nitrosomonas eutropha blocks T helper 2 cell polarization via the anti-inflammatory cytokine IL-10. Sci Rep. 2021;11:14162 pubmed 出版商
	Mata Forsberg M, Arasa C, van Zwol W, Uzunçayir S, Schönbichler A, Regenthal P, et al. Activation of human γδ T cells and NK cells by Staphylococcal enterotoxins requires both monocytes and conventional T cells. J Leukoc Biol. 2021;: pubmed 出版商
	Flament H, Rouland M, Beaudoin L, Toubal A, Bertrand L, Lebourgeois S, et al. Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity. Nat Immunol. 2021;22:322-335 pubmed 出版商
	Suliman S, Murphy M, Musvosvi M, Gela A, Meermeier E, Geldenhuys H, et al. MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria. J Immunol. 2019;203:2917-2927 pubmed 出版商
	Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X. Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling. Sci Rep. 2016;6:32320 pubmed 出版商
	Suliman S, Geldenhuys H, Johnson J, Hughes J, Smit E, Murphy M, et al. Bacillus Calmette-Guérin (BCG) Revaccination of Adults with Latent Mycobacterium tuberculosis Infection Induces Long-Lived BCG-Reactive NK Cell Responses. J Immunol. 2016;197:1100-1110 pubmed 出版商
	Bal S, Bernink J, Nagasawa M, Groot J, Shikhagaie M, Golebski K, et al. IL-1?, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs. Nat Immunol. 2016;17:636-45 pubmed 出版商
	Jones R, Mueller S, O Connor R, Rimpel K, Sloan D, Karel D, et al. A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes. PLoS Pathog. 2016;12:e1005545 pubmed 出版商
	Ranzani V, Rossetti G, Panzeri I, Arrigoni A, Bonnal R, Curti S, et al. The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4. Nat Immunol. 2015;16:318-325 pubmed 出版商
	Jo J, Tan A, Ussher J, Sandalova E, Tang X, Tan Garcia A, et al. Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver. PLoS Pathog. 2014;10:e1004210 pubmed 出版商
	Blom L, Poulsen L. IL-1 family members IL-18 and IL-33 upregulate the inflammatory potential of differentiated human Th1 and Th2 cultures. J Immunol. 2012;189:4331-7 pubmed 出版商
	Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, et al. Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property. J Immunol. 2009;183:8176-85 pubmed 出版商
	Dai Z, Turtle C, Booth G, Riddell S, Gooley T, Stevens A, et al. Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus. J Exp Med. 2009;206:793-805 pubmed 出版商
	Miller R, Sadhukhan R, Wu C. Development of an in vitro potency bioassay for therapeutic IL-13 antagonists: the A-549 cell bioassay. J Immunol Methods. 2008;334:134-41 pubmed 出版商
	Seshasayee D, Lee W, Zhou M, Shu J, Suto E, Zhang J, et al. In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation. J Clin Invest. 2007;117:3868-78 pubmed
	Mian M, Lauzon N, Stampfli M, Mossman K, Ashkar A. Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. J Leukoc Biol. 2008;83:774-84 pubmed
	Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck L, et al. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin Immunol. 2006;120:220-31 pubmed
	Radstake T, Roelofs M, Jenniskens Y, Oppers Walgreen B, van Riel P, Barrera P, et al. Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma. Arthritis Rheum. 2004;50:3856-65 pubmed
	Borg C, Jalil A, Laderach D, Maruyama K, Wakasugi H, Charrier S, et al. NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs. Blood. 2004;104:3267-75 pubmed
	Weigt H, Muhlradt P, Larbig M, Krug N, Braun A. The Toll-like receptor-2/6 agonist macrophage-activating lipopeptide-2 cooperates with IFN-gamma to reverse the Th2 skew in an in vitro allergy model. J Immunol. 2004;172:6080-6 pubmed
	Durali D, de Goër de Herve M, Giron Michel J, Azzarone B, Delfraissy J, Taoufik Y. In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment. Blood. 2003;102:4084-9 pubmed

图像

图像 1 :

IL-12 p70 antibody in Human Kidney by Immunohistochemistry (IHC-P).

产品信息

品牌 :

R&D Systems

master code :

MAB219

SKU号 :

MAB219-100

产品名称 :

IL-12 p70抗体

描述 :

The Human IL-12 p70 Antibody from R&D Systems is a mouse monoclonal antibody to IL-12 p70/IL-12A. This antibody reacts with human. The Human IL-12 p70 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Neutralization.

靶标 :

IL-12 p70

类别 :

一抗

单位尺寸 :

100 ug (also 25 ug, 500 ug)

缓冲液 :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

克隆性 :

单克隆

克隆 :

24910

共轭标签 :

未共轭

宿主 :

小鼠

免疫原 :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-12 p70

抗体亚型 :

IgG1

纯度 :

Protein A or G purified from hybridoma culture supernatant

物种 :

人类

特异性 :

Detects human IL-12 p70 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) IL-12 p40 homodimer or rhIL-23 is observed.

基因符号 :

IL12A

内毒素说明 :

<0.10 EU per 1 µg of the antibody by the LAL method.

应用 :

免疫印迹, 免疫组化, 中和反应

美元 :

453美元

别名 :

CLMF p35, CLMF1, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL12, IL12 p70, IL-12 subunit p35, IL-12, subunit p35, IL12A, interleukin 12, p35, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35), interleukin-12 alpha chain, interleukin-12 subunit alpha, natural killer cell stimulatory factor 1, 35 kD subunit, NF cell stimulatory factor chain 1, NK cell stimulatory factor chain 1, NKSF1, p35

储存 :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

更多信息或购买 :

安迪生物R&D 产品网页

公司信息

安迪生物R&D

上海市长宁区延安西路726号华敏翰尊国际大厦24A1

info@rndsystemschina.com.cn

http://www.rndsystemschina.com.cn

21 52380373

公司总部: 美国

R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.