产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
肿瘤坏死因子RI/肿瘤坏死因子受体超家族成员1A抗体
目录 :
MAB225-100
规格 :
100 ug (also 500 ug, 25 ug)
价格 :
489美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
16803
反应物种 :
人类
应用 :
免疫印迹, 中和反应, 流式细胞仪
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 28
参考文献
Lass xe9 M, El Saghir J, Berthier C, Eddy S, Fischer M, Laufer S, et al. An integrated organoid omics map extends modeling potential of kidney disease. Nat Commun. 2023;14:4903 pubmed 出版商
Pradhan L, Moore D, Ovadia E, Swedzinski S, Cossette T, Sikes R, et al. Dynamic bioinspired coculture model for probing ER+ breast cancer dormancy in the bone marrow niche. Sci Adv. 2023;9:eade3186 pubmed 出版商
Pesce B, Ribeiro C, Larrondo M, Ramos V, Soto L, Catal xe1 n D, et al. TNF-α Affects Signature Cytokines of Th1 and Th17 T Cell Subsets through Differential Actions on TNFR1 and TNFR2. Int J Mol Sci. 2022;23: pubmed 出版商
Tong O, Duette G, O Neil T, Royle C, Rana H, Johnson B, et al. Plasmacytoid dendritic cells have divergent effects on HIV infection of initial target cells and induce a pro-retention phenotype. PLoS Pathog. 2021;17:e1009522 pubmed 出版商
Lightwood D, Munro R, Porter J, McMillan D, Carrington B, Turner A, et al. A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF. Nat Commun. 2021;12:583 pubmed 出版商
Sellau J, Groneberg M, Fehling H, Thye T, Hoenow S, Marggraff C, et al. Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1. Nat Commun. 2020;11:3459 pubmed 出版商
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, et al. The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis. Oncogene. 2019;: pubmed 出版商
Minshawi F, White M, Muller W, Humphreys N, Jackson D, Campbell B, et al. Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses. Sci Rep. 2019;9:193 pubmed 出版商
Monguió Tortajada M, Franquesa M, Sarrias M, Borras F. Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes. Cell Death Dis. 2018;9:499 pubmed 出版商
Holdbrooks A, Britain C, Bellis S. ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor. J Biol Chem. 2018;293:1610-1622 pubmed 出版商
Chakraborty A, Dorsett K, Trummell H, Yang E, Oliver P, Bonner J, et al. ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage. J Biol Chem. 2018;293:984-994 pubmed 出版商
Ross S, Sherman M, McElroy P, Lofgren J, Moody G, Baeuerle P, et al. Bispecific T cell engager (BiTE®) antibody constructs can mediate bystander tumor cell killing. PLoS ONE. 2017;12:e0183390 pubmed 出版商
Morton P, Hicks A, Ortiz Zapater E, Raghavan S, Pike R, Noble A, et al. TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers. Sci Rep. 2016;6:26321 pubmed 出版商
Sonoda Y, Gohda T, Suzuki Y, Omote K, Ishizaka M, Matsuoka J, et al. Circulating TNF receptors 1 and 2 are associated with the severity of renal interstitial fibrosis in IgA nephropathy. PLoS ONE. 2015;10:e0122212 pubmed 出版商
Mizrahi K, Ash S, Peled T, Yaniv I, Stein J, Askenasy N. Negative selection by apoptosis enriches progenitors in naïve and expanded human umbilical cord blood grafts. Bone Marrow Transplant. 2014;49:942-9 pubmed 出版商
Mizrahi K, Yaniv I, Ash S, Stein J, Askenasy N. Apoptotic signaling through Fas and TNF receptors ameliorates GVHD in mobilized peripheral blood grafts. Bone Marrow Transplant. 2014;49:640-8 pubmed 出版商
Garcin G, Paul F, Staufenbiel M, Bordat Y, Van der Heyden J, Wilmes S, et al. High efficiency cell-specific targeting of cytokine activity. Nat Commun. 2014;5:3016 pubmed 出版商
Nomura T, Aoyama M, Waguri Nagaya Y, Goto Y, Suzuki M, Miyazawa K, et al. Tumor necrosis factor stimulates osteoclastogenesis from human bone marrow cells under hypoxic conditions. Exp Cell Res. 2014;321:167-77 pubmed 出版商
El Hachmane M, Rees K, Veale E, Sumbayev V, Mathie A. Enhancement of TWIK-related acid-sensitive potassium channel 3 (TASK3) two-pore domain potassium channel activity by tumor necrosis factor ?. J Biol Chem. 2014;289:1388-401 pubmed 出版商
Neumann S, Bidon T, Branschädel M, Krippner Heidenreich A, Scheurich P, Doszczak M. The transmembrane domains of TNF-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 co-regulate apoptotic signaling capacity. PLoS ONE. 2012;7:e42526 pubmed 出版商
Renaud S, Sullivan R, Graham C. Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways. Placenta. 2009;30:313-9 pubmed 出版商
Maneechotesuwan K, Wamanuttajinda V, Kasetsinsombat K, Huabprasert S, Yaikwawong M, Barnes P, et al. Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. J Allergy Clin Immunol. 2009;123:239-48 pubmed 出版商
Seal S, Hockenbery D, Spaulding E, Kiem H, Abbassi N, Deeg H. Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals. Exp Hematol. 2008;36:1660-72 pubmed 出版商
Kolliputi N, Waxman A. IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation. Am J Respir Cell Mol Biol. 2009;40:314-24 pubmed 出版商
Dong H, Kleinberg L, Silins I, Flørenes V, Trope C, Risberg B, et al. Death receptor expression is associated with poor response to chemotherapy and shorter survival in metastatic ovarian carcinoma. Cancer. 2008;112:84-93 pubmed
Ebert E, Mehta V. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell Immunol. 2006;241:7-13 pubmed
Georgopoulos N, Steele L, Thomson M, Selby P, Southgate J, Trejdosiewicz L. A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation. Cell Death Differ. 2006;13:1789-801 pubmed
Clarke D, Branton R. A role for tumor necrosis factor alpha in death of dopaminergic neurons following neural transplantation. Exp Neurol. 2002;176:154-62 pubmed
图像
图像 1 :
安迪生物R&D MAB225-100 图像 1
TNF RI/TNFRSF1A Inhibition of TNF-a-induced Cytotoxicity and Neutralization by Human TNF RI/TNFRSF1A Antibody.
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB225
SKU号 :
MAB225-100
产品名称 :
肿瘤坏死因子RI/肿瘤坏死因子受体超家族成员1A抗体
描述 :
The Human TNF RI/TNFRSF1A Antibody from R&D Systems is a mouse monoclonal antibody to TNF RI/TNFRSF1A. This antibody reacts with human. The Human TNF RI/TNFRSF1A Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Neutralization, CyTOF-ready.
靶标 :
肿瘤坏死因子RI/肿瘤坏死因子受体超家族成员1A
类别 :
一抗
单位尺寸 :
100 ug (also 500 ug, 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
16803
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
E. coli -derived recombinant human TNF RI/TNFRSF1A, Accession # NP_001056
抗体亚型 :
IgG1
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects human TNF RI in Western blots. In Western blots, does not cross-react with recombinant human (rh) TNF RII, rmTNF RI, or rmTNF RII.
基因符号 :
肿瘤坏死因子受体超家族成员1A
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
NP_001056
应用 :
Western Blot, Flow Cytometry, Neutralization, CyTOF-ready
美元 :
489美元
别名 :
CD120a, CD120a antigen, FPF, p55, p55-R, p60, TNFARMGC19588, TNF-R, TNF-R1, TNFR1TBP1, TNFR55, TNF-R55, TNFR60, TNFRI, TNF-RI, TNF-R-I, TNFR-I, TNFRSF1A, tumor necrosis factor binding protein 1, Tumor necrosis factor receptor 1, tumor necrosis factor receptor 1A isoform beta, tumor necrosis factor receptor superfamily member 1A, tumor necrosis factor receptor superfamily, member 1A, tumor necrosis factor receptor type 1, Tumor necrosis factor receptor type I, tumor necrosis factor-alpha receptor
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.