产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
Human Progranulin/PGRN Antibody
目录 :
MAB2420-SP
规格 :
25微克
价格 :
129美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
296628
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 5
参考文献
Götzl J, Brendel M, Werner G, Parhizkar S, Sebastian Monasor L, Kleinberger G, et al. Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism. EMBO Mol Med. 2019;: pubmed 出版商
Suarez Calvet M, Capell A, Araque Caballero M, Morenas Rodríguez E, Fellerer K, Franzmeier N, et al. CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. EMBO Mol Med. 2018;10: pubmed 出版商
Sleegers K, Brouwers N, Van Damme P, Engelborghs S, Gijselinck I, van der Zee J, et al. Serum biomarker for progranulin-associated frontotemporal lobar degeneration. Ann Neurol. 2009;65:603-9 pubmed 出版商
Van Damme P, Van Hoecke A, Lambrechts D, Vanacker P, Bogaert E, van Swieten J, et al. Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival. J Cell Biol. 2008;181:37-41 pubmed 出版商
Shankaran S, Capell A, Hruscha A, Fellerer K, Neumann M, Schmid B, et al. Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion. J Biol Chem. 2008;283:1744-53 pubmed
产品信息
品牌 :
R&D Systems
master code :
MAB2420
SKU号 :
MAB2420-SP
产品名称 :
Human Progranulin/PGRN Antibody
描述 :
The Human Progranulin/PGRN Antibody from R&D Systems is a mouse monoclonal antibody to Progranulin/PGRN. This antibody reacts with human. The Human Progranulin/PGRN Antibody has been validated for the following applications: Western Blot, Immunoprecipitation.
靶标 :
Progranulin/PGRN
类别 :
一抗
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in Tris and NaCl with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
296628
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human Progranulin/PGRN, Thr18-Leu593, Accession # P28799
抗体亚型 :
IgG2a
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects recombinant human Progranulin/PGRN in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse Progranulin/PGRN is observed.
基因符号 :
GRN
accessionNumbers :
P28799
应用 :
免疫印迹, 免疫沉淀
美元2021 :
119
美元2022 :
129美元
别名 :
Acrogranin, CLN11, GEP, GP88, granulin precursor, GRN, PCDGF, PEPI, PGRN, Proepithelin
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.