产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
IL-7R甲/CD127抗体
目录 :
MAB306-100
规格 :
100 ug (also 500 ug, 25 ug)
价格 :
469美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
40131
反应物种 :
人类
应用 :
免疫印迹, 流式细胞仪
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 13
参考文献
Hehenkamp P, Hoffmann M, Kummer S, Reinauer C, D xf6 ing C, F xf6 rtsch K, et al. Interleukin-7-dependent nonclassical monocytes and CD40 expression are affected in children with type 1 diabetes. Eur J Immunol. 2021;51:3214-3227 pubmed 出版商
Abdelrasoul H, Vadakumchery A, Werner M, Lenk L, Khadour A, Young M, et al. Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia. Nat Commun. 2020;11:3194 pubmed 出版商
Côté S, Burke Schinkel S, Berthoud T, Barros P, Sanchez Vidales M, Davidson A, et al. IL-7 induces sCD127 release and mCD127 downregulation in human CD8+ T cells by distinct yet overlapping mechanisms, both of which are impaired in HIV infection. Eur J Immunol. 2020;50:1537-1549 pubmed 出版商
Al Mossawi H, Yager N, Taylor C, Lau E, Danielli S, de Wit J, et al. Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele. Nat Commun. 2019;10:4575 pubmed 出版商
Kim S, Chang H, Volin M, Umar S, Van Raemdonck K, Chevalier A, et al. Macrophages are the primary effector cells in IL-7-induced arthritis. Cell Mol Immunol. 2019;: pubmed 出版商
Judge C, Kostadinova L, Sherman K, Butt A, Falck Ytter Y, Funderburg N, et al. CD56bright NK IL-7Rα expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections. J Leukoc Biol. 2017;102:171-184 pubmed 出版商
Li Y, Buijs Gladdines J, Cant Barrett K, Stubbs A, Vroegindeweij E, Smits W, et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med. 2016;13:e1002200 pubmed 出版商
Pedroza Pacheco I, Shah D, Domogala A, Luevano M, Blundell M, Jackson N, et al. Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation. Sci Rep. 2016;6:22097 pubmed 出版商
Wang S, Chen I, Liao Y, Liu C. The clinical correlation of regulatory T cells and cyclic adenosine monophosphate in enterovirus 71 infection. PLoS ONE. 2014;9:e102025 pubmed 出版商
Kreft K, Verbraak E, Wierenga Wolf A, Van Meurs M, Oostra B, Laman J, et al. Decreased systemic IL-7 and soluble IL-7R? in multiple sclerosis patients. Genes Immun. 2012;13:587-92 pubmed 出版商
Hoe E, McKay F, Schibeci S, Gandhi K, Heard R, Stewart G, et al. Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells. J Immunol. 2010;184:2512-7 pubmed 出版商
Rose T, Lambotte O, Pallier C, Delfraissy J, Colle J. Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients. J Immunol. 2009;182:7389-97 pubmed 出版商
Srivastava B, Srivastava M. Establishment and characterization of SRIK-NKL: a novel CD8+ natural killer/T cell line derived from a patient with leukemic phase of acute lymphoblastic lymphoma. Leuk Res. 2005;29:771-83 pubmed
图像
图像 1 :
安迪生物R&D MAB306-100 图像 1
Detection of IL-7 Ra/CD127 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB306
SKU号 :
MAB306-100
产品名称 :
IL-7R甲/CD127抗体
描述 :
The Human IL-7R alpha/CD127 Antibody from R&D Systems is a mouse monoclonal antibody to IL-7R alpha/CD127. This antibody reacts with human. The Human IL-7R alpha/CD127 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, CyTOF-ready.
靶标 :
IL-7R甲/CD127
类别 :
一抗
单位尺寸 :
100 ug (also 500 ug, 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
40131
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human IL-7 R alpha , Extracellular domain
抗体亚型 :
IgG1
纯度 :
蛋白质A或G纯化来自腹水
物种 :
人类
特异性 :
Detects human IL-7 R alpha in Western blots. In Western blots, approximately 5% cross-reactivity was observed with recombinant human (rh) IL-10 R, rhIL-2 R beta , rhIL-5 R alpha , and rhIL-6 R.
基因符号 :
IL7R
应用 :
Western Blot, Flow Cytometry, CyTOF-ready
美元 :
469美元
别名 :
CD127, CD127 antigen, CD127ILRA, CDW127, IL-7 R alpha, IL-7 receptor subunit alpha, IL7R, IL7R alpha, IL-7R subunit alpha, IL7RA, IL-7RA, IL-7R-alpha, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, interleukin-7 receptor subunit alpha
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.