产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
人类/小鼠CXCL12/SDF-1抗体
目录 :
MAB310
规格 :
100 ug (also 25 ug, 500 ug)
价格 :
369美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
79014
反应物种 :
人类, 小鼠
应用 :
免疫组化, 中和反应, 抑制或激活实验
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 人类; 25 ug/ml; 图 5a
Zheng J, Qu D, Wang C, Ding L, Zhou W. Involvement of CXCL12/CXCR4 in the motility of human first-trimester endometrial epithelial cells through an autocrine mechanism by activating PI3K/AKT signaling. BMC Pregnancy Childbirth. 2020;20:87 pubmed 出版商
  • 免疫组化; 人类; 1:600; 图 6
Hira V, Wormer J, Kakar H, Breznik B, van der Swaan B, Hulsbos R, et al. Periarteriolar Glioblastoma Stem Cell Niches Express Bone Marrow Hematopoietic Stem Cell Niche Proteins. J Histochem Cytochem. 2018;66:155-173 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4a
Kasagi Y, Harada Y, Morodomi Y, Iwai T, Saito S, Yoshida K, et al. Peritoneal Dissemination Requires an Sp1-Dependent CXCR4/CXCL12 Signaling Axis and Extracellular Matrix-Directed Spheroid Formation. Cancer Res. 2016;76:347-57 pubmed 出版商
Westendorp B, Büller N, Karpus O, van Dop W, Koster J, Versteeg R, et al. Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response. Cell Mol Gastroenterol Hepatol. 2018;5:67-82.e1 pubmed 出版商
Isaacson B, Hadad T, Glasner A, Gur C, Granot Z, Bachrach G, et al. Stromal Cell-Derived Factor 1 Mediates Immune Cell Attraction upon Urinary Tract Infection. Cell Rep. 2017;20:40-47 pubmed 出版商
Chen X, Yu T, Zhang J, Li Y, Chen H, Yang G, et al. CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis. Oncogene. 2017;36:5045-5057 pubmed 出版商
Guo Q, Minnier J, Burchard J, Chiotti K, Spellman P, Schedin P. Physiologically activated mammary fibroblasts promote postpartum mammary cancer. JCI Insight. 2017;2:e89206 pubmed 出版商
Hira V, Verbovšek U, Breznik B, Srdič M, Novinec M, Kakar H, et al. Cathepsin K cleavage of SDF-1? inhibits its chemotactic activity towards glioblastoma stem-like cells. Biochim Biophys Acta Mol Cell Res. 2017;1864:594-603 pubmed 出版商
Sun J, Jiao K, Niu L, Jiao Y, Song Q, Shen L, et al. Intrafibrillar silicified collagen scaffold modulates monocyte to promote cell homing, angiogenesis and bone regeneration. Biomaterials. 2017;113:203-216 pubmed 出版商
Deng Y, Cheng J, Fu B, Liu W, Chen G, Zhang Q, et al. Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells. Oncogene. 2017;36:1090-1101 pubmed 出版商
Janssens R, Mortier A, Boff D, Vanheule V, Gouwy M, Franck C, et al. Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo. Oncotarget. 2016;7:62439-62459 pubmed 出版商
Goto Y, Aoyama M, Sekiya T, Kakita H, Waguri Nagaya Y, Miyazawa K, et al. CXCR4+ CD45- Cells are Niche Forming for Osteoclastogenesis via the SDF-1, CXCL7, and CX3CL1 Signaling Pathways in Bone Marrow. Stem Cells. 2016;34:2733-2743 pubmed 出版商
Feng Y, Guo H, Yuan F, Shen M. Lipopolysaccharide Promotes Choroidal Neovascularization by Up-Regulation of CXCR4 and CXCR7 Expression in Choroid Endothelial Cell. PLoS ONE. 2015;10:e0136175 pubmed 出版商
Lin Y, Yet S, Hsu Y, Wang G, Hung S. Mesenchymal Stem Cells Ameliorate Atherosclerotic Lesions via Restoring Endothelial Function. Stem Cells Transl Med. 2015;4:44-55 pubmed 出版商
Beck T, Gomes A, Cyster J, Pereira J. CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow. J Exp Med. 2014;211:2567-81 pubmed 出版商
. Vitamin D promotes vascular regeneration. Circulation. 2014;130:976-86 pubmed 出版商
Wurster T, Tegtmeyer R, Borst O, Rath D, Geisler T, Gawaz M, et al. Platelet expression of stromal cell-derived factor-1 is associated with the degree of valvular aortic stenosis. PLoS ONE. 2014;9:e97405 pubmed 出版商
Zgraggen S, Huggenberger R, Kerl K, Detmar M. An important role of the SDF-1/CXCR4 axis in chronic skin inflammation. PLoS ONE. 2014;9:e93665 pubmed 出版商
Fleige H, Ravens S, Moschovakis G, Bölter J, Willenzon S, Sutter G, et al. IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs. J Exp Med. 2014;211:643-51 pubmed 出版商
Mocco J, Afzal A, Ansari S, Wolfe A, Caldwell K, Connolly E, et al. SDF1-a facilitates Lin-/Sca1+ cell homing following murine experimental cerebral ischemia. PLoS ONE. 2014;9:e85615 pubmed 出版商
Smith A, Bowers S, Stratman A, Davis G. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions. PLoS ONE. 2013;8:e85147 pubmed 出版商
O Boyle G, Swidenbank I, Marshall H, Barker C, Armstrong J, White S, et al. Inhibition of CXCR4-CXCL12 chemotaxis in melanoma by AMD11070. Br J Cancer. 2013;108:1634-40 pubmed 出版商
Yang Q, Kim D, Kaucher A, Oatley M, Oatley J. CXCL12-CXCR4 signaling is required for the maintenance of mouse spermatogonial stem cells. J Cell Sci. 2013;126:1009-20 pubmed 出版商
Otsuka H, Arimura N, Sonoda S, Nakamura M, Hashiguchi T, Maruyama I, et al. Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment. Am J Pathol. 2010;177:2268-77 pubmed 出版商
Wei L, Kanbe K, Lee M, Wei X, Pei M, Sun X, et al. Stimulation of chondrocyte hypertrophy by chemokine stromal cell-derived factor 1 in the chondro-osseous junction during endochondral bone formation. Dev Biol. 2010;341:236-45 pubmed 出版商
Kollmar O, Rupertus K, Scheuer C, Nickels R, Haberl G, Tilton B, et al. CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1. Int J Cancer. 2010;126:1302-15 pubmed 出版商
Ouwehand K, Santegoets S, Bruynzeel D, Scheper R, de Gruijl T, Gibbs S. CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis. Eur J Immunol. 2008;38:3050-9 pubmed 出版商
Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N. CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells. J Exp Med. 2008;205:2643-55 pubmed 出版商
Shaked Y, Henke E, Roodhart J, Mancuso P, Langenberg M, Colleoni M, et al. Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents. Cancer Cell. 2008;14:263-73 pubmed 出版商
Sasahara M, Otani A, Oishi A, Kojima H, Yodoi Y, Kameda T, et al. Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration. Am J Pathol. 2008;172:1693-703 pubmed 出版商
Lin Y, Xu L, Jin H, Zhong Y, Di J, Lin Q. CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice. Fertil Steril. 2009;91:2687-96 pubmed 出版商
Wei Y, Tang Y, Li J, Cui C, Zhang H, Zhang X, et al. Cloning and expression pattern of dog SDF-1 and the implications of altered expression of SDF-1 in ischemic myocardium. Cytokine. 2007;40:52-9 pubmed
Petty J, Sueblinvong V, Lenox C, Jones C, Cosgrove G, Cool C, et al. Pulmonary stromal-derived factor-1 expression and effect on neutrophil recruitment during acute lung injury. J Immunol. 2007;178:8148-57 pubmed
Zhu J, Garrett R, Jung Y, Zhang Y, Kim N, Wang J, et al. Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood. 2007;109:3706-12 pubmed
Massberg S, Konrad I, Schürzinger K, Lorenz M, Schneider S, Zohlnhoefer D, et al. Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo. J Exp Med. 2006;203:1221-33 pubmed
Butler J, Guthrie S, Koc M, Afzal A, Caballero S, Brooks H, et al. SDF-1 is both necessary and sufficient to promote proliferative retinopathy. J Clin Invest. 2005;115:86-93 pubmed
Liu C, Ueno T, Kuse S, Saito F, Nitta T, Piali L, et al. The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood. 2005;105:31-9 pubmed
Cardones A, Murakami T, Hwang S. CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin. Cancer Res. 2003;63:6751-7 pubmed
Villalba S, Salvucci O, Aoki Y, De La Luz Sierra M, Gupta G, Davis D, et al. Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. J Leukoc Biol. 2003;74:880-8 pubmed
产品信息
品牌 :
R&D Systems
master code :
MAB310
SKU号 :
MAB310-100
产品名称 :
人类/小鼠CXCL12/SDF-1抗体
描述 :
The Human/Mouse CXCL12/SDF-1 Antibody from R&D Systems is a mouse monoclonal antibody to CXCL12/SDF-1. This antibody reacts with human, mouse. The Human/Mouse CXCL12/SDF-1 Antibody has been validated for the following applications: Neutralization.
靶标 :
CXCL12/SDF-1
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug, 500 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
79014
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
E. coli -derived recombinant human CXCL12/SDF-1 alpha , Lys22-Lys89, Accession # Q6ICW0
抗体亚型 :
IgG1
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类, 小鼠
特异性 :
Detects human and mouse CXCL12/SDF-1 alpha and human CXCL12/SDF-1 beta .
基因符号 :
CXCL12
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB310
accessionNumbers :
Q6ICW0
应用 :
中和反应
2020美元 :
339
2021美元 :
369美元
别名 :
chemokine (C-X-C motif) ligand 12, C-X-C motif chemokine 12, hIRH, hSDF-1, Intercrine reduced in hepatomas, IRH, PBSF, PBSFSDF-1a, Pre-B cell growth-stimulating factor, SCYB12, SDF1, SDF-1, SDF1A, SDF1B, SDF1SDF-1b, stromal cell-derived factor 1, TLSF, TLSF-a, TLSF-b, TPAR1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.