产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
激活素类AβA亚单位抗体
目录 :
MAB3381-100
规格 :
100 ug (also 500 ug, 25 ug)
价格 :
459美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
69403
反应物种 :
人类, 小鼠, 大鼠
应用 :
酶联免疫吸附测定, 中和反应, 流式细胞仪
更多信息或购买 :
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 2d
Webb L, Fra Bido S, Innocentin S, Matheson L, Attaf N, Bignon A, et al. Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ. Aging Cell. 2021;20:e13295 pubmed 出版商
Culver A, Hamang M, Wang Y, Jiang H, Yanum J, White E, et al. GDF8 Contributes to Liver Fibrogenesis and Concomitant Skeletal Muscle Wasting. Biomedicines. 2023;11: pubmed 出版商
Zhu Y, Prata L, Gerdes E, Netto J, Pirtskhalava T, Giorgadze N, et al. Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans. EBioMedicine. 2022;77:103912 pubmed 出版商
Mancinelli G, Torres C, Krett N, Bauer J, Castellanos K, McKinney R, et al. Role of stromal activin A in human pancreatic cancer and metastasis in mice. Sci Rep. 2021;11:7986 pubmed 出版商
Locci M, Wu J, Arumemi F, Mikulski Z, Dahlberg C, Miller A, et al. Activin A programs the differentiation of human TFH cells. Nat Immunol. 2016;17:976-84 pubmed 出版商
Bufalino A, Cervigne N, de Oliveira C, Fonseca F, Rodrigues P, Macedo C, et al. Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis. PLoS ONE. 2015;10:e0136599 pubmed 出版商
Merfeld Clauss S, Lupov I, Lu H, March K, Traktuev D. Adipose Stromal Cell Contact with Endothelial Cells Results in Loss of Complementary Vasculogenic Activity Mediated by Induction of Activin A. Stem Cells. 2015;33:3039-51 pubmed 出版商
Sierra Filardi E, Nieto C, Dominguez Soto A, Barroso R, Sánchez Mateos P, Puig Kröger A, et al. CCL2 shapes macrophage polarization by GM-CSF and M-CSF: identification of CCL2/CCR2-dependent gene expression profile. J Immunol. 2014;192:3858-67 pubmed 出版商
Sierra Filardi E, Puig Kröger A, Blanco F, Nieto C, Bragado R, Palomero M, et al. Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers. Blood. 2011;117:5092-101 pubmed 出版商
Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J. Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB. Arthritis Rheum. 2007;56:3715-25 pubmed
Kupershmidt L, Amit T, Bar Am O, Youdim M, Blumenfeld Z. The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases. J Neurochem. 2007;103:962-71 pubmed
Greber B, Lehrach H, Adjaye J. Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal. Stem Cells. 2007;25:455-64 pubmed
Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H. Requirement of Smad3 for mast cell growth. Cell Immunol. 2006;240:47-52 pubmed
Yoshinaga K, Inoue H, Utsunomiya T, Sonoda H, Masuda T, Mimori K, et al. N-cadherin is regulated by activin A and associated with tumor aggressiveness in esophageal carcinoma. Clin Cancer Res. 2004;10:5702-7 pubmed
图像
图像 1 :
安迪生物R&D MAB3381-100 图像 1
Hemoglobin Expression Induced by Activin A and Neutralization by Human/ Mouse/Rat Activin A Antibody.
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB3381
SKU号 :
MAB3381-100
产品名称 :
激活素类AβA亚单位抗体
描述 :
The Human/Mouse/Rat Activin A beta A subunit Antibody from R&D Systems is a mouse monoclonal antibody to Activin A. This antibody reacts with human, mouse, rat. The Human/Mouse/Rat Activin A beta A subunit Antibody has been validated for the following applications: Neutralization, ELISA Capture (Matched Antibody Pair).
靶标 :
激活素类A
类别 :
一抗
单位尺寸 :
100 ug (also 500 ug, 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
69403
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Chinese hamster ovary cell line CHO-derived recombinant human Activin A
抗体亚型 :
IgG1
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类, 小鼠, 大鼠
特异性 :
Detects recombinant human Activin A in ELISAs. Also recognizes Activin A precursor. The amino acid sequences of mature beta A subunits from human, mouse and rat are identical. Therefore, this antibody will also detect the mature beta A subunit from mouse and rat.
基因符号 :
INHBA
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
应用 :
Neutralization, ELISA Capture (Matched Antibody Pair)
美元 :
459美元
别名 :
activin AB alpha polypeptide, Activin beta-A chain, erythroid differentiation factor, Erythroid differentiation protein, follicle-stimulating hormone-releasing protein, FSH-releasing protein, inhibin beta A chain, inhibin beta A subunit, Inhibin, beta-1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.