产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
Myocilin Antibody
目录 :
MAB3446
规格 :
100 ug (also 25 ug)
价格 :
449美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
297817
反应物种 :
人类
应用 :
免疫组化
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 7
参考文献
Scelsi H, Hill K, Barlow B, Martin M, Lieberman R. Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech. 2023;16: pubmed 出版商
Jasien J, Read A, van Batenburg Sherwood J, Perkumas K, Ethier C, Stamer W, et al. Anterior Segment Anatomy and Conventional Outflow Physiology of the Tree Shrew (Tupaia belangeri). Invest Ophthalmol Vis Sci. 2022;63:21 pubmed 出版商
Patterson Orazem A, Qerqez A, Azouz L, Ma M, Hill S, Ku Y, et al. Recombinant antibodies recognize conformation-dependent epitopes of the leucine zipper of misfolding-prone myocilin. J Biol Chem. 2021;297:101067 pubmed 出版商
Haribalaganesh R, Gowri Priya C, Sharmila R, Krishnadas S, Muthukkaruppan V, Willoughby C, et al. Assessment of differential intraocular pressure response to dexamethasone treatment in perfusion cultured Indian cadaveric eyes. Sci Rep. 2021;11:605 pubmed 出版商
Hill S, Kwon M, Martin M, Suntharalingam A, Hazel A, Dickey C, et al. Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations. J Biol Chem. 2019;294:12717-12728 pubmed 出版商
Suntharalingam A, Abisambra J, O Leary J, Koren J, Zhang B, Joe M, et al. Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism. J Biol Chem. 2012;287:40661-9 pubmed 出版商
Joe M, Tomarev S. Expression of myocilin mutants sensitizes cells to oxidative stress-induced apoptosis: implication for glaucoma pathogenesis. Am J Pathol. 2010;176:2880-90 pubmed 出版商
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB3446
SKU号 :
MAB3446
产品名称 :
Myocilin Antibody
描述 :
The Human Myocilin Antibody from R&D Systems is a mouse monoclonal antibody to Myocilin. This antibody reacts with human. The Human Myocilin Antibody has been validated for the following applications: Immunohistochemistry.
靶标 :
Myocilin
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
297817
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human Myocilin, Arg33-Met504, Accession # Q99972
抗体亚型 :
IgG2b
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects human Myocilin in direct ELISAs. In direct ELISAs, 75% cross-reactivity with recombinant mouse Myocilin is observed.
基因符号 :
MYOC
accessionNumbers :
Q99972
应用 :
免疫组化
美元 :
449美元
别名 :
GLC1A, GLC1Amyocilin, GPOA, JOAG, JOAG1, MYOC, myocilin, trabecular meshwork inducible glucocorticoid response, TIGR, TIGRmutated trabecular meshwork-induced glucocorticoid response protein, Trabecular meshwork-induced glucocorticoid response protein
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.