产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
ErbB3/Her3抗体
目录 :
MAB3481-100
规格 :
100 ug (also 500 ug, 25 ug)
价格 :
459美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
66223
反应物种 :
人类
应用 :
酶联免疫吸附测定, 中和反应, 流式细胞仪
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 13
参考文献
Moody T, Ramos Álvarez I, Jensen R. Adding of neurotensin to non-small cell lung cancer cells increases tyrosine phosphorylation of HER3. Peptides. 2022;156:170858 pubmed 出版商
Khan T, Seddon A, Dalgleish A, Khelwatty S, Ioannou N, Mudan S, et al. Synergistic activity of agents targeting growth factor receptors, CDKs and downstream signaling molecules in a panel of pancreatic cancer cell lines and the identification of antagonistic combinations: Implications for future clinical trials in pancr. Oncol Rep. 2020;44:2581-2594 pubmed 出版商
Wang J, Wuethrich A, Sina A, Lane R, Lin L, Wang Y, et al. Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma. Sci Adv. 2020;6:eaax3223 pubmed 出版商
Wang J, Anderson W, Li J, Lin L, Wang Y, Trau M. A high-resolution study of in situ surface-enhanced Raman scattering nanotag behavior in biological systems. J Colloid Interface Sci. 2019;537:536-546 pubmed 出版商
Memon A, Gilliver S, Borre M, Sundquist J, Sundquist K, Nexo E, et al. Soluble HER3 predicts survival in bladder cancer patients. Oncol Lett. 2018;15:1783-1788 pubmed 出版商
Le Clorennec C, BAZIN H, Dubreuil O, Larbouret C, Ogier C, Lazrek Y, et al. Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3. Mol Cancer Ther. 2017;16:1312-1323 pubmed 出版商
Puvanenthiran S, Essapen S, Seddon A, Modjtahedi H. Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of small molecule tyrosine kinase inhibitors and cytotoxic drugs. Int J Oncol. 2016;49:1825-1838 pubmed 出版商
Fock V, Plessl K, Draxler P, Otti G, Fiala C, Knöfler M, et al. Neuregulin-1-mediated ErbB2-ErbB3 signalling protects human trophoblasts against apoptosis to preserve differentiation. J Cell Sci. 2015;128:4306-16 pubmed 出版商
Liu Z, Leng E, Gunasekaran K, Pentony M, Shen M, Howard M, et al. A novel antibody engineering strategy for making monovalent bispecific heterodimeric IgG antibodies by electrostatic steering mechanism. J Biol Chem. 2015;290:7535-62 pubmed 出版商
Khelwatty S, Essapen S, Seddon A, Modjtahedi H. Growth response of human colorectal tumour cell lines to treatment with afatinib (BIBW2992), an irreversible erbB family blocker, and its association with expression of HER family members. Int J Oncol. 2011;39:483-91 pubmed 出版商
Khan I, Zhao J, Ghosh P, Ziman M, Sweeney C, Kung H, et al. Microbead arrays for the analysis of ErbB receptor tyrosine kinase activation and dimerization in breast cancer cells. Assay Drug Dev Technol. 2010;8:27-36 pubmed 出版商
Lin S, Lee Y, Choueiri M, Wen S, Mathew P, Ye X, et al. Soluble ErbB3 levels in bone marrow and plasma of men with prostate cancer. Clin Cancer Res. 2008;14:3729-36 pubmed 出版商
Lin S, Cheng C, Lee Y, Ye X, Tsai W, Kim J, et al. A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation. Oncogene. 2008;27:5195-203 pubmed 出版商
图像
图像 1 :
安迪生物R&D MAB3481-100 图像 1
Cell Proliferation Induced by NRG1-ss1/HRG1-ss1 and Neutralization by Human ErbB3/Her3 Antibody.
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB3481
SKU号 :
MAB3481-100
产品名称 :
ErbB3/Her3抗体
描述 :
The Human ErbB3/Her3 Antibody from R&D Systems is a mouse monoclonal antibody to ErbB3/Her3. This antibody reacts with human. The Human ErbB3/Her3 Antibody has been validated for the following applications: Flow Cytometry, Neutralization, CyTOF-ready, ELISA Capture (Matched Antibody Pair).
靶标 :
ErbB3/Her3
类别 :
一抗
单位尺寸 :
100 ug (also 500 ug, 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
66223
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human ErbB3/Her3, Ser20-Thr643, Accession # P21860
抗体亚型 :
IgG1
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects human ErbB3/Her3 in ELISAs. Does not cross-react with recombinant EGF R.
基因符号 :
ERBB3
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P21860
应用 :
Flow Cytometry, Neutralization, CyTOF-ready, ELISA Capture (Matched Antibody Pair)
美元 :
459美元
别名 :
c-erbB3, EC 2.7.10, EC 2.7.10.1, ErbB-3, erbB3-S, HER3, HER3c-erbB-3, LCCS2, lethal congenital contracture syndrome 2, MDA-BF-1, MGC88033, p180-ErbB3, p45-sErbB3, p85-sErbB3, Proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.