VEGFR2/KDR/Flk-1 Antibody | 安迪生物R&D MAB3572-100 产品信息

产品简要

公司名称 :

安迪生物R&D

产品类型 :

抗体

产品名称 :

VEGFR2/KDR/Flk-1 Antibody

MAB3572-100

规格 :

100 ug (also 500 ug, 25 ug)

价格 :

459美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

89106

反应物种 :

人类

应用 :

中和反应, 流式细胞仪

更多信息或购买 :

安迪生物R&D 产品网页

文章摘录数: 25

参考文献
Ghersi J, Baldissera G, Hintzen J, Luff S, Cheng S, Xia I, et al. Haematopoietic stem and progenitor cell heterogeneity is inherited from the embryonic endothelium. Nat Cell Biol. 2023;: pubmed 出版商
Doppelt Flikshtain O, Younis A, Tamari T, Ginesin O, Shentzer Kutiel T, Nikomarov D, et al. Endothelial Progenitor Cells Promote Osteosarcoma Progression and Invasiveness via AKT/PI3K Signaling. Cancers (Basel). 2023;15: pubmed 出版商
Luff S, Creamer J, Valsoni S, Dege C, Scarf xf2 R, Dacunto A, et al. Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells. Nat Cell Biol. 2022;24:616-624 pubmed 出版商
Gage B, Merlin S, Olgasi C, Follenzi A, Keller G. Therapeutic correction of hemophilia A by transplantation of hPSC-derived liver sinusoidal endothelial cell progenitors. Cell Rep. 2022;39:110621 pubmed 出版商
Dong D, Fu Y, Chen F, Zhang J, Jia H, Li J, et al. Hyperoxia sensitizes hypoxic HeLa cells to ionizing radiation by downregulating HIF‑1α and VEGF expression. Mol Med Rep. 2021;23: pubmed 出版商
Gambini E, Martinelli I, Stadiotti I, Vinci M, Scopece A, Eramo L, et al. Differences in Mitochondrial Membrane Potential Identify Distinct Populations of Human Cardiac Mesenchymal Progenitor Cells. Int J Mol Sci. 2020;21: pubmed 出版商
Tamari T, Kawar Jaraisy R, Doppelt O, Giladi B, Sabbah N, Zigdon Giladi H. The Paracrine Role of Endothelial Cells in Bone Formation via CXCR4/SDF-1 Pathway. Cells. 2020;9: pubmed 出版商
Koehler L, Ruiz Gómez G, Balamurugan K, Rother S, Freyse J, Moller S, et al. Dual Action of Sulfated Hyaluronan on Angiogenic Processes in Relation to Vascular Endothelial Growth Factor-A. Sci Rep. 2019;9:18143 pubmed 出版商
Toledo Pons N, Noell G, Jahn A, Iglesias A, Durán M, Iglesias J, et al. Bone marrow characterization in COPD: a multi-level network analysis. Respir Res. 2018;19:118 pubmed 出版商
Otto S, Nitsche K, Jung C, Kryvanos A, Zhylka A, Heitkamp K, et al. Endothelial progenitor cells and plaque burden in stented coronary artery segments: an optical coherence tomography study six months after elective PCI. BMC Cardiovasc Disord. 2017;17:103 pubmed 出版商
Odent Grigorescu G, Rosca A, Preda M, Tutuianu R, Simionescu M, Burlacu A. Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells. J Tissue Eng Regen Med. 2017;11:3241-3252 pubmed 出版商
Silva I, Salhi A, Giles K, Vogelsang M, Han S, Ismaili N, et al. Identification of a Novel Pathogenic Germline KDR Variant in Melanoma. Clin Cancer Res. 2016;22:2377-85 pubmed 出版商
Fleetwood F, Klint S, Hanze M, Gunneriusson E, Frejd F, StÃ¥hl S, et al. Simultaneous targeting of two ligand-binding sites on VEGFR2 using biparatopic Affibody molecules results in dramatically improved affinity. Sci Rep. 2014;4:7518 pubmed 出版商
Jarajapu Y, Hazra S, Segal M, Li Calzi S, LiCalzi S, Jadhao C, et al. Vasoreparative dysfunction of CD34+ cells in diabetic individuals involves hypoxic desensitization and impaired autocrine/paracrine mechanisms. PLoS ONE. 2014;9:e93965 pubmed 出版商
Goretti E, Rolland Turner M, Léonard F, Zhang L, Wagner D, Devaux Y. MicroRNA-16 affects key functions of human endothelial progenitor cells. J Leukoc Biol. 2013;93:645-55 pubmed 出版商
Facciabene A, Peng X, Hagemann I, Balint K, Barchetti A, Wang L, et al. Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature. 2011;475:226-30 pubmed 出版商
Byeon S, Lee S, Choi S, Lee H, Lee J, Chu Y, et al. Vascular endothelial growth factor as an autocrine survival factor for retinal pigment epithelial cells under oxidative stress via the VEGF-R2/PI3K/Akt. Invest Ophthalmol Vis Sci. 2010;51:1190-7 pubmed 出版商
Riccioni R, Senese M, Diverio D, Riti V, Mariani G, Boe A, et al. Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels. Leuk Res. 2008;32:1244-58 pubmed 出版商
Ohsaka A, Hirota Komatsu S, Shibata M, Ezaki J, Shinohara F, Yoshida T. Specific association of increased vascular endothelial growth factor expression and its receptors with macrophage differentiation of HL-60 leukemia cells. Biochem Biophys Res Commun. 2008;368:543-9 pubmed 出版商
Lin Y, Liang Y, Chiang B. Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. J Leukoc Biol. 2007;82:1473-80 pubmed
Ball S, Shuttleworth C, Kielty C. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol. 2007;177:489-500 pubmed
Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, et al. Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. Stem Cells. 2007;25:1862-71 pubmed
Rajesh D, Chinnasamy N, Mitalipov S, Wolf D, Slukvin I, Thomson J, et al. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007;25:490-9 pubmed
Caldas H, Fangusaro J, Boue D, Holloway M, Altura R. Dissecting the role of endothelial SURVIVIN DeltaEx3 in angiogenesis. Blood. 2007;109:1479-89 pubmed
Sreekumar P, Kannan R, de Silva A, Burton R, Ryan S, Hinton D. Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells. Biochem Biophys Res Commun. 2006;346:1200-6 pubmed

图像

图像 1 :

Detection of VEGFR2/KDR/Flk-1 antibody in HUVEC Human Cells antibody by Flow Cytometry.

产品信息

品牌 :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB3572

SKU号 :

MAB3572-100

产品名称 :

VEGFR2/KDR/Flk-1 Antibody

描述 :

The Human VEGFR2/KDR/Flk-1 Antibody from R&D Systems is a mouse monoclonal antibody to VEGFR2/KDR/Flk-1. This antibody reacts with human. The Human VEGFR2/KDR/Flk-1 Antibody has been validated for the following applications: Flow Cytometry, Neutralization, CyTOF-ready.

靶标 :

VEGFR2/KDR/Flk-1

类别 :

一抗

单位尺寸 :

100 ug (also 500 ug, 25 ug)

缓冲液 :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

克隆性 :

单克隆

克隆 :

89106

共轭标签 :

未共轭

宿主 :

小鼠

免疫原 :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGFR2/KDR/Flk-1, Ala20-Glu764, Accession # P35968

抗体亚型 :

IgG1

纯度 :

Protein A or G purified from hybridoma culture supernatant

物种 :

人类

特异性 :

Detects human VEGFR2/KDR/Flk-1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) VEGFR1, rhVEGFR3 or recombinant mouse VEGFR2 is observed.

基因符号 :

激酶插入区受体

内毒素说明 :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

P35968

应用 :

Flow Cytometry, Neutralization, CyTOF-ready

美元 :

459美元

别名 :

CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, Flk1, Flk-1, FLK1tyrosine kinase growth factor receptor, KDR, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGF R2, VEGFR, VEGFR2, VEGFR-2

储存 :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

更多信息或购买 :

安迪生物R&D 产品网页

公司信息

安迪生物R&D

上海市长宁区延安西路726号华敏翰尊国际大厦24A1

info@rndsystemschina.com.cn

http://www.rndsystemschina.com.cn

21 52380373

公司总部: 美国

R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.