产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
TrkB Antibody
目录 :
MAB397-100
规格 :
100 ug (also 500 ug, 25 ug)
价格 :
459美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
75133
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 6
参考文献
Xiong J, Liao J, Liu X, Zhang Z, Adams J, Pacifici R, et al. A TrkB agonist prodrug prevents bone loss via inhibiting asparagine endopeptidase and increasing osteoprotegerin. Nat Commun. 2022;13:4820 pubmed 出版商
Wang Z, Xiang J, Liu X, Yu S, Manfredsson F, Sandoval I, et al. Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer's Disease. Cell Rep. 2019;28:655-669.e5 pubmed 出版商
Tanaka K, Okugawa Y, Toiyama Y, Inoue Y, Saigusa S, Kawamura M, et al. Brain-derived neurotrophic factor (BDNF)-induced tropomyosin-related kinase B (Trk B) signaling is a potential therapeutic target for peritoneal carcinomatosis arising from colorectal cancer. PLoS ONE. 2014;9:e96410 pubmed 出版商
Rossing K, Novak N, Mommert S, Pfab F, Gehring M, Wedi B, et al. Brain-derived neurotrophic factor is increased in serum and skin levels of patients with chronic spontaneous urticaria. Clin Exp Allergy. 2011;41:1392-9 pubmed 出版商
Raap U, Fokkens W, Bruder M, Hoogsteden H, Kapp A, Braunstahl G. Modulation of neurotrophin and neurotrophin receptor expression in nasal mucosa after nasal allergen provocation in allergic rhinitis. Allergy. 2008;63:468-75 pubmed 出版商
Gleissner C, Zastrow A, Klingenberg R, Kluger M, Konstandin M, Celik S, et al. IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells. Eur J Immunol. 2007;37:177-92 pubmed
图像
图像 1 :
安迪生物R&D MAB397-100 图像 1
Detection of Human, Mouse, and Rat TrkB antibody by Western Blot.
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB397
SKU号 :
MAB397-100
产品名称 :
TrkB Antibody
描述 :
The Human/Mouse/Rat TrkB Antibody from R&D Systems is a mouse monoclonal antibody to TrkB. This antibody reacts with human, mouse, rat. The Human/Mouse/Rat TrkB Antibody has been validated for the following applications: Western Blot, Immunohistochemistry.
靶标 :
TrkB
类别 :
一抗
单位尺寸 :
100 ug (also 500 ug, 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
75133
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human TrkB, Cys32-His430, Accession # Q16620
抗体亚型 :
IgG2b
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类, 小鼠, 大鼠
特异性 :
Detects human TrkB in direct ELISAs. Detects human, mouse, and rat TrkB in Western blots. In ELISAs and Western blots, no cross-reactivity with recombinant human (rh) TrkA, rhTrkC, or recombinant rat TrkA is observed.
基因符号 :
NTRK2
accessionNumbers :
Q16620
应用 :
免疫印迹, 免疫组化
美元 :
459美元
别名 :
BDNF/NT-3 growth factors receptor, EC 2.7.10, EC 2.7.10.1, GP145-TrkB, Neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, NTRK2, trk-B, TrkB tyrosine kinase, TRKBBDNF-tropomyosine receptor kinase B, tyrosine kinase receptor B
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.