产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲抗体
目录 :
MAB4101
规格 :
100 ug (also 25 ug)
价格 :
469美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
MP6-XT22
反应物种 :
小鼠
应用 :
中和反应, 抑制或激活实验
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 小鼠; 图 7c
Shi L, Wang J, Ding N, Zhang Y, Zhu Y, Dong S, et al. Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy. Nat Commun. 2019;10:5421 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 s2
Kassem A, Lindholm C, Lerner U. Toll-Like Receptor 2 Stimulation of Osteoblasts Mediates Staphylococcus Aureus Induced Bone Resorption and Osteoclastogenesis through Enhanced RANKL. PLoS ONE. 2016;11:e0156708 pubmed 出版商
  • 抑制或激活实验; 小鼠
Chucair Elliott A, Conrady C, Zheng M, Kroll C, Lane T, Carr D. Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells. Glia. 2014;62:1418-34 pubmed 出版商
  • 抑制或激活实验; 小鼠
Notomi S, Hisatomi T, Kanemaru T, Takeda A, Ikeda Y, Enaida H, et al. Critical involvement of extracellular ATP acting on P2RX7 purinergic receptors in photoreceptor cell death. Am J Pathol. 2011;179:2798-809 pubmed 出版商
  • 抑制或激活实验; 小鼠
Cappello P, Caorsi C, Bosticardo M, De Angelis S, Novelli F, Forni G, et al. CCL16/LEC powerfully triggers effector and antigen-presenting functions of macrophages and enhances T cell cytotoxicity. J Leukoc Biol. 2004;75:135-42 pubmed
Oh J, Riek A, Bauerle K, Dusso A, McNerney K, Barve R, et al. Embryonic vitamin D deficiency programs hematopoietic stem cells to induce type 2 diabetes. Nat Commun. 2023;14:3278 pubmed 出版商
Cai J, Hu D, Sakya J, Sun T, Wang D, Wang L, et al. ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer. Cell Death Dis. 2021;12:140 pubmed 出版商
Liu Z, Nailwal H, Rector J, Rahman M, Sam R, McFadden G, et al. A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation. Immunity. 2021;54:247-258.e7 pubmed 出版商
Song G, Rahman M, Jha M, Gupta D, Park S, Kim J, et al. A Bcr-Abl Inhibitor GNF-2 Attenuates Inflammatory Activation of Glia and Chronic Pain. Front Pharmacol. 2019;10:543 pubmed 出版商
Handa P, Thomas S, Morgan Stevenson V, Maliken B, Gochanour E, Boukhar S, et al. Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis. J Leukoc Biol. 2019;105:1015-1026 pubmed 出版商
John B, Naczki C, Patel C, Ghoneum A, Qasem S, Salih Z, et al. Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC. Oncogene. 2019;38:4366-4383 pubmed 出版商
Chhana A, Pool B, Callon K, Tay M, Musson D, Naot D, et al. Monosodium urate crystals reduce osteocyte viability and indirectly promote a shift in osteocyte function towards a proinflammatory and proresorptive state. Arthritis Res Ther. 2018;20:208 pubmed 出版商
Quiroga D, Muñoz M, Gil C, Pffeifer M, Toblli J, Steckelings U, et al. Chronic administration of the angiotensin type 2 receptor agonist C21 improves insulin sensitivity in C57BL/6 mice. Physiol Rep. 2018;6:e13824 pubmed 出版商
Cook A, Lee M, Saleh R, Khiew H, Christensen A, Achuthan A, et al. TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17. JCI Insight. 2018;3: pubmed 出版商
Burg A, Das S, Padgett L, Koenig Z, Tse H. Superoxide Production by NADPH Oxidase Intensifies Macrophage Antiviral Responses during Diabetogenic Coxsackievirus Infection. J Immunol. 2018;200:61-70 pubmed 出版商
Tavares R, Pathak S. Helicobacter pylori Secreted Protein HP1286 Triggers Apoptosis in Macrophages via TNF-Independent and ERK MAPK-Dependent Pathways. Front Cell Infect Microbiol. 2017;7:58 pubmed 出版商
Schock S, Chandra N, Sun Y, Irie T, Kitagawa Y, Gotoh B, et al. Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway. Cell Death Differ. 2017;24:615-625 pubmed 出版商
Prasad S, Starck S, Shastri N. Presentation of Cryptic Peptides by MHC Class I Is Enhanced by Inflammatory Stimuli. J Immunol. 2016;197:2981-2991 pubmed
Dankbar B, Fennen M, Brunert D, Hayer S, Frank S, Wehmeyer C, et al. Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice. Nat Med. 2015;21:1085-90 pubmed 出版商
Berod L, Stüve P, Swallow M, Arnold Schrauf C, Kruse F, Gentilini M, et al. MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection. Eur J Immunol. 2014;44:1399-409 pubmed 出版商
Ruiz E, Oeztuerk Winder F, Ventura J. A paracrine network regulates the cross-talk between human lung stem cells and the stroma. Nat Commun. 2014;5:3175 pubmed 出版商
Bhargava R, Altmann C, Andres Hernando A, Webb R, Okamura K, Yang Y, et al. Acute lung injury and acute kidney injury are established by four hours in experimental sepsis and are improved with pre, but not post, sepsis administration of TNF-? antibodies. PLoS ONE. 2013;8:e79037 pubmed 出版商
Pathak S, Tavares R, de Klerk N, Spetz A, Jonsson A. Helicobacter pylori protein JHP0290 binds to multiple cell types and induces macrophage apoptosis via tumor necrosis factor (TNF)-dependent and independent pathways. PLoS ONE. 2013;8:e77872 pubmed 出版商
Gardner T, Chen Q, Jin Y, Ajuebor M. Toll-like receptor 3 ligand dampens liver inflammation by stimulating Valpha 14 invariant natural killer T cells to negatively regulate gammadeltaT cells. Am J Pathol. 2010;176:1779-89 pubmed 出版商
Ismail N, Crossley E, Stevenson H, Walker D. Relative importance of T-cell subsets in monocytotropic ehrlichiosis: a novel effector mechanism involved in Ehrlichia-induced immunopathology in murine ehrlichiosis. Infect Immun. 2007;75:4608-20 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB4101
SKU号 :
MAB4101
产品名称 :
肿瘤坏死因子甲抗体
描述 :
The Mouse TNF-alpha Antibody from R&D Systems is a rat monoclonal antibody to TNF-alpha. This antibody reacts with mouse. The Mouse TNF-alpha Antibody has been validated for the following applications: Neutralization, Intracellular Staining by Flow Cytometry.
靶标 :
肿瘤坏死因子甲
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
MP6-XT22
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
大鼠
免疫原 :
小鼠肿瘤坏死因子甲
抗体亚型 :
IgG1
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
小鼠
特异性 :
Detects mouse TNF-alpha .
基因符号 :
肿瘤坏死因子
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
应用 :
Neutralization, Intracellular Staining by Flow Cytometry
美元 :
469美元
别名 :
APC1 protein, Cachectin, Cachetin, DIF, TNF, TNF, monocyte-derived, TNF-a, TNFA, TNFalpha, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFG1F, TNFSF1A, TNFSF2, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.