产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
Mouse CD3 epsilon Antibody
目录 :
MAB484
规格 :
100 ug (also 25 ug, 500 ug)
价格 :
369美元
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
未共轭
克隆名称 :
145-2C11
反应物种 :
人类, 小鼠
应用 :
免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 23
参考文献
Prenek L, Litvai T, Balázs N, Kugyelka R, Boldizsar F, Najbauer J, et al. Regulatory T cells are less sensitive to glucocorticoid hormone induced apoptosis than CD4+ T cells. Apoptosis. 2020;25:715-729 pubmed 出版商
Sidles S, Xiong Y, Young M, LaRue A. High-Fat Diet Alters Immunogenic Properties of Circulating and Adipose Tissue-Associated Myeloid-Derived CD45+DDR2+ Cells. Mediators Inflamm. 2019;2019:1648614 pubmed 出版商
Klein F, Mitrovic M, Roux J, Engdahl C, von Muenchow L, Albertí Servera L, et al. The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection. J Exp Med. 2019;216:638-655 pubmed 出版商
Atretkhany K, Mufazalov I, Dunst J, Kuchmiy A, Gogoleva V, Andruszewski D, et al. Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity. Proc Natl Acad Sci U S A. 2018;115:13051-13056 pubmed 出版商
Engelowski E, Modares N, Gorressen S, Bouvain P, Semmler D, Alter C, et al. IL-23R Signaling Plays No Role in Myocardial Infarction. Sci Rep. 2018;8:17078 pubmed 出版商
Savinko T, Guenther C, Uotila L, Llort Asens M, Yao S, Tojkander S, et al. Filamin A Is Required for Optimal T Cell Integrin-Mediated Force Transmission, Flow Adhesion, and T Cell Trafficking. J Immunol. 2018;200:3109-3116 pubmed 出版商
Mantani P, Dunér P, Bengtsson E, Ljungcrantz I, Sundius L, To F, et al. Interleukin-25 (IL-25) has a protective role in atherosclerosis development in the aortic arch in mice. J Biol Chem. 2018;293:6791-6801 pubmed 出版商
Johnson R, Yu H, Strank N, Karunakaran K, Zhu Y, Brunham R. B Cell Presentation of Chlamydia Antigen Selects Out Protective CD4?13 T Cells: Implications for Genital Tract Tissue-Resident Memory Lymphocyte Clusters. Infect Immun. 2018;86: pubmed 出版商
McDonald L, Johnson S, Russell D, Young M, LaRue A. Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis. PLoS ONE. 2017;12:e0180724 pubmed 出版商
Chung J, Ebens C, Perkey E, Radojcic V, Koch U, Scarpellino L, et al. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest. 2017;127:1574-1588 pubmed 出版商
Chen H, Wang P, Su H, Wang W, Chu Z, Zhang L, et al. mTORC2 controls Th9 polarization and allergic airway inflammation. Allergy. 2017;72:1510-1520 pubmed 出版商
Kinosada H, Yasunaga J, Shimura K, Miyazato P, Onishi C, Iyoda T, et al. HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors. PLoS Pathog. 2017;13:e1006120 pubmed 出版商
Gupta S, Marcel N, Talwar S, Garg M, R I, Perumalsamy L, et al. Developmental heterogeneity in DNA packaging patterns influences T-cell activation and transmigration. PLoS ONE. 2012;7:e43718 pubmed 出版商
Jones G, Stumhofer J, Foster T, Twohig J, Hertzog P, Topley N, et al. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J. 2011;25:409-19 pubmed 出版商
Jones G, McLoughlin R, Hammond V, Parker C, Williams J, Malhotra R, et al. Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. J Immunol. 2010;184:2130-9 pubmed 出版商
Sinclair L, Finlay D, Feijoo C, Cornish G, Gray A, Ager A, et al. Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nat Immunol. 2008;9:513-21 pubmed 出版商
Onoyama I, Tsunematsu R, Matsumoto A, Kimura T, de Alboran I, Nakayama K, et al. Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis. J Exp Med. 2007;204:2875-88 pubmed
Li W, Kashiwamura S, Ueda H, Sekiyama A, Okamura H. Protection of CD8+ T cells from activation-induced cell death by IL-18. J Leukoc Biol. 2007;82:142-51 pubmed
Gérard A, Mertens A, van der Kammen R, Collard J. The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization. J Cell Biol. 2007;176:863-75 pubmed
Bheeshmachar G, Purushotaman D, Sade H, Gunasekharan V, Rangarajan A, Sarin A. Evidence for a role for notch signaling in the cytokine-dependent survival of activated T cells. J Immunol. 2006;177:5041-50 pubmed
Ogilvie R, Abelson M, Hau H, Vlasova I, Blackshear P, Bohjanen P. Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay. J Immunol. 2005;174:953-61 pubmed
Kipnis J, Cardon M, Avidan H, Lewitus G, Mordechay S, Rolls A, et al. Dopamine, through the extracellular signal-regulated kinase pathway, downregulates CD4+CD25+ regulatory T-cell activity: implications for neurodegeneration. J Neurosci. 2004;24:6133-43 pubmed
Hirata T, Merrill Skoloff G, Aab M, Yang J, Furie B, Furie B. P-Selectin glycoprotein ligand 1 (PSGL-1) is a physiological ligand for E-selectin in mediating T helper 1 lymphocyte migration. J Exp Med. 2000;192:1669-76 pubmed
产品信息
品牌 :
R&D Systems
master code :
MAB484
SKU号 :
MAB484-100
产品名称 :
Mouse CD3 epsilon Antibody
描述 :
The Mouse CD3 epsilon Antibody from R&D Systems is a hamster monoclonal antibody to CD3 epsilon. This antibody reacts with mouse. The Mouse CD3 epsilon Antibody has been validated for the following applications: Flow Cytometry, Immunoprecipitation, Cell depletion, T Cell Stimulation, CyTOF-reported.
靶标 :
CD3 epsilon
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug, 500 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
145-2C11
共轭标签 :
未共轭
宿主 :
仓鼠
免疫原 :
H-2Kb小鼠细胞毒性T淋巴细胞
抗体亚型 :
IgG
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
小鼠
特异性 :
Detects mouse CD3 epsilon . Binds to lymphocytes from all mouse strains tested and does not react with cells from rats, rabbits, miniature swine, or hamsters.1 Binds to the CD3 epsilon-chain present on T-lymphocyes and thymocytes. Its binding has been characterized with respect to several other monoclonal anti-CD3 antibodies.3,4
基因符号 :
Cd247
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB484
应用 :
Flow Cytometry, Immunoprecipitation, Cell depletion, T Cell Stimulation, CyTOF-reported
2020美元 :
339
2021美元 :
369美元
别名 :
CD3e, CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.