产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
小鼠CCL17/TARC抗体
目录 :
MAB529-SP
规格 :
25微克
价格 :
119美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
110904
反应物种 :
人类, 小鼠
应用 :
酶联免疫吸附测定, 中和反应
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 15
参考文献
Deng S, Jin P, Sherchan P, Liu S, Cui Y, Huang L, et al. Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice. J Neuroinflammation. 2021;18:62 pubmed 出版商
Lee M, Saleh R, Achuthan A, Fleetwood A, Forster I, Hamilton J, et al. CCL17 blockade as a therapy for osteoarthritis pain and disease. Arthritis Res Ther. 2018;20:62 pubmed 出版商
Cook A, Lee M, Saleh R, Khiew H, Christensen A, Achuthan A, et al. TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17. JCI Insight. 2018;3: pubmed 出版商
Fülle L, Steiner N, Funke M, Gondorf F, Pfeiffer F, Siegl J, et al. RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In Vivo. Mol Ther. 2018;26:95-104 pubmed 出版商
Thanabalasuriar A, Neupane A, Wang J, Krummel M, Kubes P. iNKT Cell Emigration out of the Lung Vasculature Requires Neutrophils and Monocyte-Derived Dendritic Cells in Inflammation. Cell Rep. 2016;16:3260-3272 pubmed 出版商
Achuthan A, Cook A, Lee M, Saleh R, Khiew H, Chang M, et al. Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation. J Clin Invest. 2016;126:3453-66 pubmed 出版商
Santulli Marotto S, Boakye K, Lacy E, Wu S, Luongo J, Kavalkovich K, et al. Engagement of two distinct binding domains on CCL17 is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung. PLoS ONE. 2013;8:e81465 pubmed 出版商
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed 出版商
Specht S, Frank J, Alferink J, Dubben B, Layland L, Denece G, et al. CCL17 controls mast cells for the defense against filarial larval entry. J Immunol. 2011;186:4845-52 pubmed 出版商
Kearley J, Buckland K, Mathie S, Lloyd C. Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway. Am J Respir Crit Care Med. 2009;179:772-81 pubmed 出版商
HENRY C, Ornelles D, Mitchell L, Brzoza Lewis K, Hiltbold E. IL-12 produced by dendritic cells augments CD8+ T cell activation through the production of the chemokines CCL1 and CCL17. J Immunol. 2008;181:8576-84 pubmed
Kearley J, Robinson D, Lloyd C. CD4+CD25+ regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling. J Allergy Clin Immunol. 2008;122:617-24.e6 pubmed 出版商
Meyer E, Wurbel M, Staton T, Pichavant M, Kan M, Savage P, et al. iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity. J Immunol. 2007;179:4661-71 pubmed
Fujita H, Asahina A, Komine M, Tamaki K. The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells. Cell Immunol. 2007;245:70-9 pubmed
Bengtsson A, Ryan E, Giordano D, Magaletti D, Clark E. 17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells. Blood. 2004;104:1404-10 pubmed
图像
图像 1 :
安迪生物R&D MAB529-SP 图像 1
Chemotaxis Induced by CCL17/TARC and Neutralization by Mouse CCL17/TARC Antibody.
产品信息
品牌 :
R&D Systems
master code :
MAB529
SKU号 :
MAB529-SP
产品名称 :
小鼠CCL17/TARC抗体
描述 :
The Mouse CCL17/TARC Antibody from R&D Systems is a rat monoclonal antibody to CCL17/TARC. This antibody reacts with mouse. The Mouse CCL17/TARC Antibody has been validated for the following applications: Neutralization, ELISA Capture (Matched Antibody Pair).
靶标 :
CCL17/TARC
类别 :
一抗
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
110904
共轭标签 :
未共轭
宿主 :
大鼠
免疫原 :
E. coli -derived Recombinant Mouse CCL17/TARC, Ala24-Pro93, Accession # Q9WUZ6
抗体亚型 :
IgG2a
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
小鼠
特异性 :
Detects mouse CCL17/TARC in ELISAs.
基因符号 :
CCL17
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
Q9WUZ6
应用 :
Neutralization, ELISA Capture (Matched Antibody Pair)
美元2021 :
109
美元2022 :
119美元
别名 :
ABCD-2, CC chemokine TARC, C-C motif chemokine 17, chemokine (C-C motif) ligand 17, MGC138273, SCYA17, SCYA17MGC138271, small inducible cytokine subfamily A (Cys-Cys), member 17, Small-inducible cytokine A17, T cell-directed CC chemokine, TARC, TARCA-152E5.3, Thymus and activation-regulated chemokine
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.