产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
IL-2抗体
目录 :
MAB602-100
规格 :
100 ug (also 25 ug, 500 ug)
价格 :
453美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
5355
反应物种 :
人类
应用 :
酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
文章摘录数: 14
参考文献
Dwyer C, Arhontoulis D, Rangel Rivera G, Knochelmann H, Smith A, Wyatt M, et al. Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8+ T cells. Eur J Immunol. 2020;50:1386-1399 pubmed 出版商
Bryson B, Rosebrock T, Tafesse F, Itoh C, Nibasumba A, Babunovic G, et al. Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis. Nat Commun. 2019;10:2329 pubmed 出版商
Caudana P, Núñez N, de la Rochere P, Pinto A, Denizeau J, Alonso R, et al. IL2/Anti-IL2 Complex Combined with CTLA-4, But Not PD-1, Blockade Rescues Antitumor NK Cell Function by Regulatory T-cell Modulation. Cancer Immunol Res. 2019;7:443-457 pubmed 出版商
Whitfield S, Taylor C, Risdall J, Griffiths G, Jones J, Williamson E, et al. Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology. J Immunol. 2017;198:3989-3998 pubmed 出版商
Chamoto K, Guo T, Scally S, Kagoya Y, Anczurowski M, Wang C, et al. Key Residues at Third CDR3? Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs. J Immunol. 2017;198:1056-1065 pubmed 出版商
Rochman Y, Yukawa M, Kartashov A, Barski A. Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig. PLoS ONE. 2015;10:e0122198 pubmed 出版商
Levin A, Bates D, Ring A, Krieg C, Lin J, Su L, et al. Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'. Nature. 2012;484:529-33 pubmed 出版商
Rubinstein M, Lind N, Purton J, Filippou P, Best J, McGhee P, et al. IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood. 2008;112:3704-12 pubmed 出版商
Biancotto A, Iglehart S, Lisco A, Vanpouille C, Grivel J, Lurain N, et al. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res Hum Retroviruses. 2008;24:453-62 pubmed 出版商
Pfleger C, Schloot N, ter Veld F. Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. J Immunol Methods. 2008;329:214-8 pubmed
Grivel J, Elliott J, Lisco A, Biancotto A, Condack C, Shattock R, et al. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1. AIDS. 2007;21:1263-72 pubmed
Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed
Pavon L, Sandoval López G, Eugenia Hernández M, Loría F, Estrada I, Perez M, et al. Th2 cytokine response in Major Depressive Disorder patients before treatment. J Neuroimmunol. 2006;172:156-65 pubmed
Farah I, Mola P, Kariuki T, Nyindo M, Blanton R, King C. Repeated exposure induces periportal fibrosis in Schistosoma mansoni-infected baboons: role of TGF-beta and IL-4. J Immunol. 2000;164:5337-43 pubmed
图像
图像 1 :
安迪生物R&D MAB602-100 图像 1
IL-2 antibody in Human PBMCs by Immunocytochemistry (ICC).
产品信息
品牌 :
R&D Systems
master code :
MAB602
SKU号 :
MAB602-100
产品名称 :
IL-2抗体
描述 :
The Human/Primate IL-2 Antibody from R&D Systems is a mouse monoclonal antibody to IL-2. This antibody reacts with human, primate. The Human/Primate IL-2 Antibody has been validated for the following applications: Immunocytochemistry, ELISA Capture (Matched Antibody Pair).
靶标 :
IL-2
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug, 500 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
5355
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
E. coli -derived recombinant human IL-2, Ala21-Thr153, Accession # NP_000577
抗体亚型 :
IgG2a
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类, 灵长类动物
特异性 :
Detects human and primate IL-2 in ELISAs. In sandwich immunoassays, no cross-reactivity with recombinant human (rh) IL-1 alpha , rhIL-1 beta , rhIL-3, rhIL-4, rhIL-6, rhIL-7, rhIL-8, recombinant mouse (rm) IL-1 beta , rmIL-2, rmIL-3, rmIL-4, rmIL-5, rmIL-6, or rmIL-7 is observed.
基因符号 :
白细胞介素
accessionNumbers :
NP_000577
应用 :
Immunocytochemistry, ELISA Capture (Matched Antibody Pair)
美元 :
453美元
别名 :
aldesleukin, IL2, IL-2, IL-2lymphokine, interleukin 2, interleukin-2, involved in regulation of T-cell clonal expansion, Proleukin, T cell growth factor, T-cell growth factor, TCGF
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.