产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
人类TRAIL R2/TNFRSF10B抗体
目录 :
MAB631
规格 :
100 ug (also 25 ug, 500 ug)
价格 :
359美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
71903
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 s7b
Pan L, Fu T, Zhao W, Zhao L, Chen W, Qiu C, et al. Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling. Cell. 2019;176:1477-1489.e14 pubmed 出版商
Bloomer D, Kitevska Ilioski T, Pantaki Eimany D, Ji Y, Miles M, Heras B, et al. CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants. Biochem J. 2019;476:1335-1357 pubmed 出版商
Boettcher M, Covarrubias S, Biton A, Blau J, Wang H, Zaitlen N, et al. Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding. BMC Genomics. 2019;20:107 pubmed 出版商
Kang Z, Goldstein S, Yu Y, Meltzer P, Loeb D, Cao L. Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma. Br J Cancer. 2015;113:894-901 pubmed 出版商
Bozza W, Di X, Takeda K, Rivera Rosado L, Pariser S, Zhang B. The use of a stably expressed FRET biosensor for determining the potency of cancer drugs. PLoS ONE. 2014;9:e107010 pubmed 出版商
Meng X, Koh B, Zhang J, Flatten K, Schneider P, Billadeau D, et al. Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression. J Biol Chem. 2014;289:20543-58 pubmed
Matte I, Lane D, Boivin M, Rancourt C, Piche A. MUC16 mucin (CA125) attenuates TRAIL-induced apoptosis by decreasing TRAIL receptor R2 expression and increasing c-FLIP expression. BMC Cancer. 2014;14:234 pubmed 出版商
Kang Z, Chen J, Yu Y, Li B, Sun S, Zhang B, et al. Drozitumab, a human antibody to death receptor 5, has potent antitumor activity against rhabdomyosarcoma with the expression of caspase-8 predictive of response. Clin Cancer Res. 2011;17:3181-92 pubmed 出版商
Stary G, Klein I, Kohlhofer S, Koszik F, Scherzer T, Müllauer L, et al. Plasmacytoid dendritic cells express TRAIL and induce CD4+ T-cell apoptosis in HIV-1 viremic patients. Blood. 2009;114:3854-63 pubmed 出版商
Locklin R, Federici E, Espina B, Hulley P, Russell R, Edwards C. Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis. Mol Cancer Ther. 2007;6:3219-28 pubmed
Shigeno M, Nakao K, Ichikawa T, Suzuki K, Kawakami A, Abiru S, et al. Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation. Oncogene. 2003;22:1653-62 pubmed
产品信息
品牌 :
R&D Systems
master code :
MAB631
SKU号 :
MAB631-100
产品名称 :
人类TRAIL R2/TNFRSF10B抗体
描述 :
The Human TRAIL R2/TNFRSF10B Antibody from R&D Systems is a mouse monoclonal antibody to TRAILR2/TNFRSF10B. This antibody reacts with human. The Human TRAIL R2/TNFRSF10B Antibody has been validated for the following applications: Agonist Activity.
靶标 :
TRAILR2/TNFRSF10B
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug, 500 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
71903
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human TRAIL R2/TNFRSF10B, Met1-Glu182, Accession # CAG46696
抗体亚型 :
IgG1
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects human TRAIL R2/TNFRSF10B in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) TRAIL R1, rhTRAIL R3, rhTRAIL R4, or rhDcR3.
基因符号 :
TNFRSF10B
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB631
accessionNumbers :
CAG46696
应用 :
Agonist Activity
2020美元 :
339
2021美元 :
359美元
别名 :
CD262, CD262 antigen, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAILR2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.