产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
TRAIL R2/TNFRSF10B抗体
目录 :
MAB6311
规格 :
500 ug (also 25 ug)
价格 :
549美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
71908
反应物种 :
人类, 小鼠
应用 :
流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类
Labovsky V, Martinez L, Davies K, Garcia Rivello H, Calcagno M, Matas A, et al. Association between ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells. Clin Breast Cancer. 2015;15:e13-21 pubmed 出版商
  • 流式细胞仪; 人类
Stenqvist A, Nagaeva O, Baranov V, Mincheva Nilsson L. Exosomes secreted by human placenta carry functional Fas ligand and TRAIL molecules and convey apoptosis in activated immune cells, suggesting exosome-mediated immune privilege of the fetus. J Immunol. 2013;191:5515-23 pubmed 出版商
  • 流式细胞仪; 小鼠
Neumann S, Bidon T, Branschädel M, Krippner Heidenreich A, Scheurich P, Doszczak M. The transmembrane domains of TNF-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 co-regulate apoptotic signaling capacity. PLoS ONE. 2012;7:e42526 pubmed 出版商
  • 流式细胞仪; 人类
Moniri M, Sun X, Rayat J, Dai D, Ao Z, He Z, et al. TRAIL-engineered pancreas-derived mesenchymal stem cells: characterization and cytotoxic effects on pancreatic cancer cells. Cancer Gene Ther. 2012;19:652-8 pubmed 出版商
  • 流式细胞仪; 人类; 5 ug/ml
Moriwaki K, Shinzaki S, Miyoshi E. GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation. J Biol Chem. 2011;286:43123-33 pubmed 出版商
  • 流式细胞仪; 人类
Zauli G, Rimondi E, Celeghini C, Milani D, Secchiero P. Dexamethasone counteracts the anti-osteoclastic, but not the anti-leukemic, activity of TNF-related apoptosis inducing ligand (TRAIL). J Cell Physiol. 2010;222:357-64 pubmed 出版商
  • 流式细胞仪; 人类
Stary G, Klein I, Kohlhofer S, Koszik F, Scherzer T, Müllauer L, et al. Plasmacytoid dendritic cells express TRAIL and induce CD4+ T-cell apoptosis in HIV-1 viremic patients. Blood. 2009;114:3854-63 pubmed 出版商
  • 流式细胞仪; 人类
Seal S, Hockenbery D, Spaulding E, Kiem H, Abbassi N, Deeg H. Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals. Exp Hematol. 2008;36:1660-72 pubmed 出版商
  • 流式细胞仪; 人类
Toscano F, Fajoui Z, Gay F, Lalaoui N, Parmentier B, Chayvialle J, et al. P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells. Oncogene. 2008;27:4161-71 pubmed 出版商
  • 流式细胞仪; 人类
Weinmann L, Wischhusen J, Demma M, Naumann U, Roth P, Dasmahapatra B, et al. A novel p53 rescue compound induces p53-dependent growth arrest and sensitises glioma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ. 2008;15:718-29 pubmed 出版商
  • 流式细胞仪; 人类
Barbarotto E, Corallini F, Rimondi E, Fadda R, Mischiati C, Grill V, et al. Differential effects of chemotherapeutic drugs versus the MDM-2 antagonist nutlin-3 on cell cycle progression and induction of apoptosis in SKW6.4 lymphoblastoid B-cells. J Cell Biochem. 2008;104:595-605 pubmed
Boccellato C, Kolbe E, Peters N, Juric V, Fullstone G, Verreault M, et al. Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist. Cell Death Dis. 2021;12:647 pubmed 出版商
Bachsais M, Salti S, Zaoui K, Hassan G, Aoudjit F, Mourad W. CD154 inhibits death of T cells via a Cis interaction with the α5β1 integrin. PLoS ONE. 2020;15:e0235753 pubmed 出版商
Stöhr D, Schmid J, Beigl T, Mack A, Maichl D, Cao K, et al. Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids. Cell Death Differ. 2020;: pubmed 出版商
Lee S, Hyun S, Kim H, Kang C, Kim S. Potential Role of CD133 Expression in the Susceptibility of Human Liver Cancer Stem-Like Cells to TRAIL. Oncol Res. 2016;24:495-509 pubmed 出版商
Takano S, Ishikawa E, Matsuda M, Yamamoto T, Matsumura A. Interferon-β inhibits glioma angiogenesis through downregulation of vascular endothelial growth factor and upregulation of interferon inducible protein 10. Int J Oncol. 2014;45:1837-46 pubmed 出版商
Neumann S, Hasenauer J, Pollak N, Scheurich P. Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes. J Biol Chem. 2014;289:16576-87 pubmed 出版商
Tang X, Lu J, Tu H, Huang K, Fu R, Cao G, et al. TRAIL-engineered bone marrow-derived mesenchymal stem cells: TRAIL expression and cytotoxic effects on C6 glioma cells. Anticancer Res. 2014;34:729-34 pubmed
Suzuki Karasaki M, Ochiai T, Suzuki Karasaki Y. Crosstalk between mitochondrial ROS and depolarization in the potentiation of TRAIL-induced apoptosis in human tumor cells. Int J Oncol. 2014;44:616-28 pubmed 出版商
Zhou Y, Tian L, Long L, Quan M, Liu F, Cao J. Casticin potentiates TRAIL-induced apoptosis of gastric cancer cells through endoplasmic reticulum stress. PLoS ONE. 2013;8:e58855 pubmed 出版商
Siegemund M, Pollak N, Seifert O, Wahl K, Hanak K, Vogel A, et al. Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity. Cell Death Dis. 2012;3:e295 pubmed 出版商
Shankar S, Chen Q, Ganapathy S, Singh K, Srivastava R. Diallyl trisulfide increases the effectiveness of TRAIL and inhibits prostate cancer growth in an orthotopic model: molecular mechanisms. Mol Cancer Ther. 2008;7:2328-38 pubmed 出版商
Dunn C, Brunetto M, Reynolds G, Christophides T, Kennedy P, Lampertico P, et al. Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage. J Exp Med. 2007;204:667-80 pubmed
Singh T, Shankar S, Srivastava R. HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma. Oncogene. 2005;24:4609-23 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB6311
SKU号 :
MAB6311
产品名称 :
TRAIL R2/TNFRSF10B抗体
描述 :
The Human TRAIL R2/TNFRSF10B Antibody from R&D Systems is a mouse monoclonal antibody to TRAILR2/TNFRSF10B. This antibody reacts with human. The Human TRAIL R2/TNFRSF10B Antibody has been validated for the following applications: Flow Cytometry, CyTOF-ready.
靶标 :
TRAIL R2/TNFRSF10B
类别 :
一抗
单位尺寸 :
500 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
71908
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human TRAIL R2/TNFRSF10B, Ile56-Glu182, Accession # O14763
抗体亚型 :
IgG2b
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects human TRAIL R2 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) TRAIL R1, rhTRAIL R3, rhTRAIL R4, or recombinant mouse TRAIL R2.
基因符号 :
TNFRSF10B
accessionNumbers :
O14763
应用 :
Flow Cytometry, CyTOF-ready
美元 :
549美元
别名 :
CD262, CD262 antigen, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAILR2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.