产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
Wnt 5a抗体
目录 :
MAB645
规格 :
100 ug (also 25 ug)
价格 :
469美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
442625
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 27
出版应用/物种/样本/稀释参考文献
  • 免疫印迹基因敲除验证; 人类; 1:300; 图 1c
Han B, Zhou B, Qu Y, Gao B, Xu Y, Chung S, et al. FOXC1-induced non-canonical WNT5A-MMP7 signaling regulates invasiveness in triple-negative breast cancer. Oncogene. 2018;37:1399-1408 pubmed 出版商
  • 免疫印迹; 人类; 图 2d, 3f
  • 免疫印迹; 小鼠; 图 1a
Baarsma H, Skronska Wasek W, Mutze K, Ciolek F, Wagner D, John Schuster G, et al. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD. J Exp Med. 2017;214:143-163 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1
Li D, Sinha T, Ajima R, Seo H, Yamaguchi T, Wang J. Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deployment. Dev Biol. 2016;412:18-31 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Bleckmann A, Conradi L, Menck K, Schmick N, Schubert A, Rietkötter E, et al. β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases. Clin Exp Metastasis. 2016;33:309-23 pubmed 出版商
  • 免疫印迹; 小鼠; 1:250; 图 3
Easter S, Mitchell E, Baxley S, Desmond R, Frost A, Serra R. Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors. PLoS ONE. 2014;9:e113247 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2a
Buttler K, Becker J, Pukrop T, Wilting J. Maldevelopment of dermal lymphatics in Wnt5a-knockout-mice. Dev Biol. 2013;381:365-76 pubmed 出版商
  • 免疫印迹; 人类
Barbolina M, Burkhalter R, Stack M. Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment. Biochem J. 2011;437:1-12 pubmed 出版商
Nualart F, Cifuentes M, Ram xed rez E, Mart xed nez F, Barahona M, Ferrada L, et al. Hyperglycemia increases SCO-spondin and Wnt5a secretion into the cerebrospinal fluid to regulate ependymal cell beating and glucose sensing. PLoS Biol. 2023;21:e3002308 pubmed 出版商
Yadav V, Jobe N, Satapathy S, Mohapatra P, Andersson T. Increased MARCKS Activity in BRAF Inhibitor-Resistant Melanoma Cells Is Essential for Their Enhanced Metastatic Behavior Independent of Elevated WNT5A and IL-6 Signaling. Cancers (Basel). 2022;14: pubmed 出版商
Lee G, Kim Y, Park B, Yim S, Park C, Roh H, et al. YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity. Cell Death Dis. 2022;13:407 pubmed 出版商
Radaszkiewicz T, Nosková M, Gömöryová K, Vondálová Blanárová O, Radaszkiewicz K, Pícková M, et al. RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy. elife. 2021;10: pubmed 出版商
Kaiser K, Jang A, Kompaníková P, Lun M, Prochazka J, Machon O, et al. MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development. 2021;148: pubmed 出版商
Shao Y, Zhu F, Zhu S, Bai L. HDAC6 suppresses microRNA-199a transcription and augments HPV-positive cervical cancer progression through Wnt5a upregulation. Int J Biochem Cell Biol. 2021;136:106000 pubmed 出版商
Asem M, Young A, Oyama C, Claure De La Zerda A, Liu Y, Yang J, et al. Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis. Cancer Res. 2020;80:1156-1170 pubmed 出版商
Hasan M, Rassenti L, Widhopf G, Yu J, Kipps T. Wnt5a causes ROR1 to complex and activate cortactin to enhance migration of chronic lymphocytic leukemia cells. Leukemia. 2019;33:653-661 pubmed 出版商
Huang T, Lee P, Wu M, Huang C, Ko C, Lee Y, et al. Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells. PLoS ONE. 2017;12:e0181034 pubmed 出版商
Vesel M, Rapp J, Feller D, Kiss E, Jaromi L, Meggyes M, et al. ABCB1 and ABCG2 drug transporters are differentially expressed in non-small cell lung cancers (NSCLC) and expression is modified by cisplatin treatment via altered Wnt signaling. Respir Res. 2017;18:52 pubmed 出版商
Jung H, Byun H, Jee B, Min S, Jeoun U, Lee Y, et al. The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence. J Biol Chem. 2017;292:3729-3739 pubmed 出版商
Prasad C, Chaurasiya S, Guilmain W, Andersson T. WNT5A signaling impairs breast cancer cell migration and invasion via mechanisms independent of the epithelial-mesenchymal transition. J Exp Clin Cancer Res. 2016;35:144 pubmed 出版商
Fuster J, Zuriaga M, Ngo D, Farb M, Aprahamian T, Yamaguchi T, et al. Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. Diabetes. 2015;64:1235-48 pubmed 出版商
MacMillan C, Leong H, Dales D, Robertson A, Lewis J, Chambers A, et al. Stage of breast cancer progression influences cellular response to activation of the WNT/planar cell polarity pathway. Sci Rep. 2014;4:6315 pubmed 出版商
Linnskog R, Jonsson G, Axelsson L, Prasad C, Andersson T. Interleukin-6 drives melanoma cell motility through p38?-MAPK-dependent up-regulation of WNT5A expression. Mol Oncol. 2014;8:1365-78 pubmed 出版商
Zhao Y, Wang C, Li R, Hui T, Su Y, Yuan Q, et al. Wnt5a promotes inflammatory responses via nuclear factor ?B (NF-?B) and mitogen-activated protein kinase (MAPK) pathways in human dental pulp cells. J Biol Chem. 2014;289:21028-39 pubmed
Popp T, Steinritz D, Breit A, Deppe J, Egea V, Schmidt A, et al. Wnt5a/β-catenin signaling drives calcium-induced differentiation of human primary keratinocytes. J Invest Dermatol. 2014;134:2183-2191 pubmed 出版商
Yap L, Ahmad M, Zabidi M, Chu T, Chai S, Lee H, et al. Oncogenic effects of WNT5A in Epstein-Barr virus‑associated nasopharyngeal carcinoma. Int J Oncol. 2014;44:1774-80 pubmed 出版商
Menck K, Klemm F, Gross J, Pukrop T, Wenzel D, Binder C. Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles. Oncotarget. 2013;4:2057-66 pubmed
Halleskog C, Dijksterhuis J, Kilander M, Becerril Ortega J, Villaescusa J, Lindgren E, et al. Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation. J Neuroinflammation. 2012;9:111 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB645
SKU号 :
MAB645
产品名称 :
Wnt 5a抗体
描述 :
The Human/Mouse Wnt-5a Antibody from R&D Systems is a rat monoclonal antibody to Wnt-5a. This antibody reacts with human, mouse. The Human/Mouse Wnt-5a Antibody has been validated for the following applications: Immunohistochemistry.
靶标 :
Wnt-5a
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
442625
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
大鼠
免疫原 :
CHO-derived recombinant mouse Wnt-5a, Gln38-Lys380, Accession # P22725
抗体亚型 :
IgG2a
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类, 小鼠
特异性 :
Detects mouse Wnt-5a in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Wnt-1, 2b, 3a, 4, 5b, 8a, 8b, 9b, 10a, 10b, 11, or 16 is observed.
基因符号 :
WNT5A
accessionNumbers :
P22725
应用 :
免疫组化
美元 :
469美元
别名 :
hWNT5A, protein Wnt-5a, wingless-type MMTV integration site family, member 5A, Wnt5a, WNT-5A protein
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.