产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
小鼠IL-17/IL-17A抗体
目录 :
MAB721-500
规格 :
500微克
价格 :
849美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
50101
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 17
参考文献
Lee S, Kwon J, Kim S, Jung K, Cho M. Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis. Sci Rep. 2017;7:10133 pubmed 出版商
Lv R, Zhao J, Lei M, Xiao D, Yu Y, Xie J. IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3. Cell Physiol Biochem. 2017;42:1961-1972 pubmed 出版商
Yau A, Tuncel J, Holmdahl R. The Major Histocompatibility Complex Class III Haplotype Ltab-Ncr3 Regulates Adjuvant-Induced but Not Antigen-Induced Autoimmunity. Am J Pathol. 2017;187:987-998 pubmed 出版商
Tuncel J, Haag S, Holmdahl R. MHC class II alleles associated with Th1 rather than Th17 type immunity drive the onset of early arthritis in a rat model of rheumatoid arthritis. Eur J Immunol. 2017;47:563-574 pubmed 出版商
Griffiths K, Ahmed M, Das S, Gopal R, Horne W, Connell T, et al. Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy. Nat Commun. 2016;7:13894 pubmed 出版商
Lim J, Im K, Lee E, Kim N, Nam Y, Jeon Y, et al. Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis. Sci Rep. 2016;6:26851 pubmed 出版商
Monin L, Griffiths K, Slight S, Lin Y, Rangel Moreno J, Khader S. Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge. Mucosal Immunol. 2015;8:1099-109 pubmed 出版商
Zhang X, Schaumburg C, Coursey T, Siemasko K, Volpe E, Gandhi N, et al. CD8? cells regulate the T helper-17 response in an experimental murine model of Sjögren syndrome. Mucosal Immunol. 2014;7:417-27 pubmed 出版商
Lee J, Lee J, Park M, Lim M, Park E, Kim E, et al. Interferon gamma suppresses collagen-induced arthritis by regulation of Th17 through the induction of indoleamine-2,3-deoxygenase. PLoS ONE. 2013;8:e60900 pubmed 出版商
Costa M, Bornstein V, Candéa A, Henriques Pons A, Henriques M, Penido C. CCL25 induces ???? integrin-dependent migration of IL-17? ?? T lymphocytes during an allergic reaction. Eur J Immunol. 2012;42:1250-60 pubmed 出版商
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed 出版商
Lemos H, Grespan R, Vieira S, Cunha T, Verri W, Fernandes K, et al. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production. Proc Natl Acad Sci U S A. 2009;106:5954-9 pubmed 出版商
Muranski P, Boni A, Antony P, Cassard L, Irvine K, Kaiser A, et al. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood. 2008;112:362-73 pubmed 出版商
Sheibanie A, Yen J, Khayrullina T, Emig F, Zhang M, Tuma R, et al. The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis. J Immunol. 2007;178:8138-47 pubmed
Lockhart E, Green A, Flynn J. IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J Immunol. 2006;177:4662-9 pubmed
Khader S, Pearl J, Sakamoto K, Gilmartin L, Bell G, Jelley Gibbs D, et al. IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available. J Immunol. 2005;175:788-95 pubmed
Lubberts E, Joosten L, Oppers B, van den Bersselaar L, Coenen de Roo C, Kolls J, et al. IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis. J Immunol. 2001;167:1004-13 pubmed
图像
图像 1 :
安迪生物R&D MAB721-500 图像 1
Detection of Recombinant Mouse and Rat IL-17/IL-17A antibody by Western Blot.
产品信息
品牌 :
R&D Systems
master code :
MAB721
SKU号 :
MAB721-500
产品名称 :
小鼠IL-17/IL-17A抗体
描述 :
The Mouse IL-17/IL-17A Antibody from R&D Systems is a rat monoclonal antibody to IL-17/IL-17A. This antibody reacts with mouse. The Mouse IL-17/IL-17A Antibody has been validated for the following applications: Western Blot, ELISA Capture (Matched Antibody Pair).
靶标 :
IL-17/IL-17A
类别 :
一抗
单位尺寸 :
500微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
50101
共轭标签 :
未共轭
宿主 :
大鼠
免疫原 :
E. coli -derived recombinant mouse IL-17, Thr22-Ala158, Accession # Q62386
抗体亚型 :
IgG2a
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
小鼠
特异性 :
Detects mouse IL-17 in ELISAs and Western blots. In direct ELISAs, 100% reactivity with recombinant mouse (rm) IL-17A/IL-17F heterodimer, 50% cross-reactivity with recombinant human IL-17, and 25% cross-reactivity with recombinant canine IL-17 is observed. No cross-reactivity with rmIL-17B, rmIL-17C, rmIL-17D, rmIL-17E, or rmIL-17F is observed. In Western blots, cross-reactivity with recombinant rat IL-17A is observed.
基因符号 :
IL17A
accessionNumbers :
Q62386
应用 :
Western Blot, ELISA Capture (Matched Antibody Pair)
美元2021 :
799
美元2022 :
849美元
别名 :
CTLA8, CTLA-8, CTLA8cytotoxic T淋巴细胞 丝氨酸酯酶8, 细胞毒性T淋巴细胞 抗原8, 白细胞介素-17, IL17A, IL-17A, IL-17Acytotoxic T淋巴细胞 蛋白8, IL-17CTLA-8, IL17interleukin-17A, 白细胞介素17(细胞毒性T淋巴细胞 丝氨酸酯酶8), 白细胞介素17A
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.