产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
人类/小鼠NLRP3/NALP3抗体
目录 :
MAB7578-SP
规格 :
25微克
价格 :
135美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
768319
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 24
参考文献
Wang Y, Chen S, Yang P, Chen J, Kong W, Wang Y. AIM2 inflammasome activation may mediate high mobility group box 1 release in murine allergic rhinitis. Braz J Otorhinolaryngol. 2021;: pubmed 出版商
Oliveira A, Pereira M, Belew A, Ferreira L, Pereira L, Neves E, et al. Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation. PLoS Pathog. 2020;16:e1008781 pubmed 出版商
Serini S, Guarino R, Ottes Vasconcelos R, Celleno L, Calviello G. The Combination of Sulforaphane and Fernblock® XP Improves Individual Beneficial Effects in Normal and Neoplastic Human Skin Cell Lines. Nutrients. 2020;12: pubmed 出版商
Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, et al. Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype. Cell Death Dis. 2020;11:377 pubmed 出版商
Lecoeur H, Prina E, Rosazza T, Kokou K, N Diaye P, Aulner N, et al. Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response. Cell Rep. 2020;30:1870-1882.e4 pubmed 出版商
Ferreira N, Bruder Nascimento T, Pereira C, Zanotto C, Prado D, Silva J, et al. NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus. Cells. 2019;8: pubmed 出版商
Chang C, Shih H, Huang I, Tsai P, Chen K, Huang C. Magnesium Sulfate Mitigates the Progression of Monocrotaline Pulmonary Hypertension in Rats. Int J Mol Sci. 2019;20: pubmed 出版商
Samir P, Kesavardhana S, Patmore D, Gingras S, Malireddi R, Karki R, et al. DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome. Nature. 2019;573:590-594 pubmed 出版商
Lancaster G, Langley K, Berglund N, Kammoun H, Reibe S, Estevez E, et al. Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism. Cell Metab. 2018;27:1096-1110.e5 pubmed 出版商
Boursereau R, Abou Samra M, Lecompte S, Noel L, Brichard S. Downregulation of the NLRP3 inflammasome by adiponectin rescues Duchenne muscular dystrophy. BMC Biol. 2018;16:33 pubmed 出版商
Gugliandolo A, Giacoppo S, Ficicchia M, Aliquò A, Bramanti P, Mazzon E. Eruca sativa seed extract: A novel natural product able to counteract neuroinflammation. Mol Med Rep. 2018;17:6235-6244 pubmed 出版商
Gong D, Zhang Y, Chen D, Hong L, Han F, Liu Q, et al. Endothelial GPR124 Exaggerates the Pathogenesis of Atherosclerosis by Activating Inflammation. Cell Physiol Biochem. 2018;45:547-557 pubmed 出版商
Kosmidou C, Efstathiou N, Hoang M, Notomi S, Konstantinou E, Hirano M, et al. Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration. Sci Rep. 2018;8:461 pubmed 出版商
DeWolf S, Shigeoka A, Scheinok A, Kasimsetty S, Welch A, McKay D. Expression of TLR2, NOD1, and NOD2 and the NLRP3 Inflammasome in Renal Tubular Epithelial Cells of Male versus Female Mice. Nephron. 2017;137:68-76 pubmed 出版商
Yang A, Inamine T, Hochrath K, Chen P, Wang L, Llorente C, et al. Intestinal fungi contribute to development of alcoholic liver disease. J Clin Invest. 2017;127:2829-2841 pubmed 出版商
Daley D, Mani V, Mohan N, Akkad N, Pandian G, Savadkar S, et al. NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma. J Exp Med. 2017;214:1711-1724 pubmed 出版商
Chen X, Wang N, Zhu Y, Lu Y, Liu X, Zheng J. The Antimalarial Chloroquine Suppresses LPS-Induced NLRP3 Inflammasome Activation and Confers Protection against Murine Endotoxic Shock. Mediators Inflamm. 2017;2017:6543237 pubmed 出版商
Bian F, Xiao Y, Zaheer M, Volpe E, Pflugfelder S, Li D, et al. Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn. Int J Mol Sci. 2017;18: pubmed 出版商
Hu Z, Zhang Y, Wang J, Mao P, Lv X, Yuan S, et al. Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light. Cell Death Dis. 2016;7:e2468 pubmed 出版商
Kim Y, Wang W, Okla M, Kang I, Moreau R, Chung S. Suppression of NLRP3 inflammasome by γ-tocotrienol ameliorates type 2 diabetes. J Lipid Res. 2016;57:66-76 pubmed 出版商
Liu X, Hu Z, Zhou B, Li X, Tao R. Chinese Herbal Preparation Xuebijing Potently Inhibits Inflammasome Activation in Hepatocytes and Ameliorates Mouse Liver Ischemia-Reperfusion Injury. PLoS ONE. 2015;10:e0131436 pubmed 出版商
Antonopoulos C, Russo H, El Sanadi C, Martin B, Li X, Kaiser W, et al. Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling. J Biol Chem. 2015;290:20167-84 pubmed 出版商
Maier N, Leppla S, Moayeri M. The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes. J Immunol. 2015;194:2776-85 pubmed 出版商
Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, et al. ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction. Am J Pathol. 2014;184:1287-98 pubmed 出版商
图像
图像 1 :
安迪生物R&D MAB7578-SP 图像 1
Detection of Mouse NLRP3/NALP3 antibody by Western Blot.
产品信息
品牌 :
R&D Systems
master code :
MAB7578
SKU号 :
MAB7578-SP
产品名称 :
人类/小鼠NLRP3/NALP3抗体
描述 :
The Human/Mouse NLRP3/NALP3 Antibody from R&D Systems is a rat monoclonal antibody to NLRP3/NALP3. This antibody reacts with human, mouse. The Human/Mouse NLRP3/NALP3 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready.
靶标 :
NLRP3/NALP3
类别 :
一抗
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
768319
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
大鼠
免疫原 :
E. coli -derived recombinant mouse NLRP3/NALP3, Met1-Arg153, Accession # Q8R4B8
抗体亚型 :
IgG2a
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类, 小鼠
特异性 :
Detects mouse NLRP3/NALP3 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human NLRP3/NALP3 is observed.
基因符号 :
NLRP3
accessionNumbers :
Q8R4B8
应用 :
Western Blot, Immunohistochemistry, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready
美元2021 :
129
美元2022 :
135美元
别名 :
AGTAVPRL, AII, AII/AVP, Angiotensin/vasopressin receptor AII/AVP-like, AVP, C1orf7, Caterpiller protein 1.1, CIAS1, CLR1.1, Cold autoinflammatory syndrome 1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, Familial cold autoinflammatory syndrome, FCAS, FCU, Leucine-rich repeat-, and PYD-containing protein 3, Muckle-Wells syndrome, MWS, NACHT, NACHT, LRR and PYD containing protein 3, NACHT, LRR and PYD domains-containing protein 3, NALP3, NLR family, pyrin domain containing 3, NLRP3, Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin Domain Containing 3, PYPAF1, PYRIN-containing APAF1-like protein 1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.