组织蛋白酶L抗体 | 安迪生物R&D MAB9521-100 产品信息

产品简要

公司名称 :

安迪生物R&D

产品类型 :

抗体

产品名称 :

组织蛋白酶L抗体

MAB9521-100

规格 :

100 ug (also 500 ug, 25 ug)

价格 :

459美元

克隆性 :

单克隆

宿主 :

大鼠

共轭标签 :

未共轭

克隆名称 :

204101

反应物种 :

人类

应用 :

免疫印迹, 免疫组化, 免疫沉淀

更多信息或购买 :

安迪生物R&D 产品网页

文章摘录数: 10

参考文献
Sarkar C, Jones J, Hegdekar N, Thayer J, Kumar A, Faden A, et al. PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma. Autophagy. 2019;:1-20 pubmed 出版商
Pavel M, Imarisio S, Menzies F, Jimenez Sanchez M, Siddiqi F, Wu X, et al. CCT complex restricts neuropathogenic protein aggregation via autophagy. Nat Commun. 2016;7:13821 pubmed 出版商
Yang M, Liang C, Swaminathan K, Herrlinger S, Lai F, Shiekhattar R, et al. A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy. Sci Adv. 2016;2:e1601167 pubmed 出版商
Pensa S, Neoh K, Resemann H, Kreuzaler P, Abell K, Clarke N, et al. The PI3K regulatory subunits p55? and p50? regulate cell death in vivo. Cell Death Differ. 2014;21:1442-50 pubmed 出版商
O Brien J, Martinson H, Durand Rougely C, Schedin P. Macrophages are crucial for epithelial cell death and adipocyte repopulation during mammary gland involution. Development. 2012;139:269-75 pubmed 出版商
Kreuzaler P, Staniszewska A, Li W, Omidvar N, Kedjouar B, Turkson J, et al. Stat3 controls lysosomal-mediated cell death in vivo. Nat Cell Biol. 2011;13:303-9 pubmed 出版商
Lopez Castejon G, Theaker J, Pelegrin P, Clifton A, Braddock M, Surprenant A. P2X(7) receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases. J Immunol. 2010;185:2611-9 pubmed 出版商
Zeeuwen P, van Vlijmen Willems I, Cheng T, Rodijk Olthuis D, Hitomi K, Hara Nishimura I, et al. The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea. FASEB J. 2010;24:3744-55 pubmed 出版商
Parker B, Ciocca D, Bidwell B, Gago F, Fanelli M, George J, et al. Primary tumour expression of the cysteine cathepsin inhibitor Stefin A inhibits distant metastasis in breast cancer. J Pathol. 2008;214:337-46 pubmed
Cheng T, Hitomi K, van Vlijmen Willems I, de Jongh G, Yamamoto K, Nishi K, et al. Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. J Biol Chem. 2006;281:15893-9 pubmed

图像

图像 1 :

Detection of Recombinant Human and Mouse Cathepsin L antibody by Western Blot.

产品信息

品牌 :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB9521

SKU号 :

MAB9521-100

产品名称 :

组织蛋白酶L抗体

描述 :

The Human/Mouse Cathepsin L Antibody from R&D Systems is a rat monoclonal antibody to Cathepsin L. This antibody reacts with human, mouse. The Human/Mouse Cathepsin L Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunoprecipitation.

靶标 :

组织蛋白酶L

类别 :

一抗

单位尺寸 :

100 ug (also 500 ug, 25 ug)

缓冲液 :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

克隆性 :

单克隆

克隆 :

204101

共轭标签 :

未共轭

宿主 :

大鼠

免疫原 :

Mouse myeloma cell line NS0-derived recombinant human Cathepsin L, Glu113-Val333, Accession # P07711

抗体亚型 :

IgG2a

纯度 :

Protein A or G purified from hybridoma culture supernatant

物种 :

人类, 小鼠

特异性 :

Detects human and mouse Cathepsin L in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Cathepsin B, C, L2, O, S, or X/Z/P is observed. In Western blots, both the pro and active forms of recombinant human and mouse Cathspsin L are recognized.

基因符号 :

CTSL1

accessionNumbers :

P07711

应用 :

免疫印迹, 免疫组化, 免疫沉淀

美元 :

459美元

别名 :

cathepsin L, cathepsin L1, CATL, CTSL, CTSL1, CTSLEC 3.4.22.15, EC 3.4.22, FLJ31037, Major excreted protein, MEP

储存 :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

更多信息或购买 :

安迪生物R&D 产品网页

公司信息

安迪生物R&D

上海市长宁区延安西路726号华敏翰尊国际大厦24A1

info@rndsystemschina.com.cn

http://www.rndsystemschina.com.cn

21 52380373

公司总部: 美国

R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.