产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
Recombinant Human Poly-Ub WT Chains (2-7) (K48-linked), CF
目录 :
UC-230-100
规格 :
100微克
价格 :
254美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 9
参考文献
Hage A, Bharaj P, van Tol S, Giraldo M, Gonzalez Orozco M, Valerdi K, et al. The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity. Cell Rep. 2022;38:110434 pubmed 出版商
Zammit N, Siggs O, Gray P, Horikawa K, Langley D, Walters S, et al. Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity. Nat Immunol. 2019;20:1299-1310 pubmed 出版商
Chai Q, Wang X, Qiang L, Zhang Y, Ge P, Lu Z, et al. A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy. Nat Commun. 2019;10:1973 pubmed 出版商
Brickner J, Soll J, Lombardi P, Vågbø C, Mudge M, Oyeniran C, et al. A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair. Nature. 2017;551:389-393 pubmed 出版商
Xu P, Hankins H, MacDonald C, Erlinger S, Frazier M, Diab N, et al. COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal. elife. 2017;6: pubmed 出版商
Lu K, den Brave F, Jentsch S. Receptor oligomerization guides pathway choice between proteasomal and autophagic degradation. Nat Cell Biol. 2017;19:732-739 pubmed 出版商
Luijsterburg M, Typas D, Caron M, Wiegant W, van den Heuvel D, Boonen R, et al. A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation. elife. 2017;6: pubmed 出版商
Zhong H, Wang D, Fang L, Zhang H, Luo R, Shang M, et al. Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling. PLoS ONE. 2013;8:e80976 pubmed 出版商
Zhao Y, Zhu H, Zou M. Non-covalent interaction between polyubiquitin and GTP cyclohydrolase 1 dictates its degradation. PLoS ONE. 2012;7:e43306 pubmed 出版商
产品信息
品牌 :
R&D Systems
master code :
UC-230
SKU号 :
UC-230-100
产品名称 :
Recombinant Human Poly-Ub WT Chains (2-7) (K48-linked), CF
单位尺寸 :
100微克
描述 :
The AQUApure Phospho-Tetra-Ub Chains (K48, pS65) Protein, CF from R&D Systems is derived from E. coli. The AQUApure Phospho-Tetra-Ub Chains (K48, pS65) Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
Poly-Ubiquitin
类别 :
蛋白和酶
别名 :
CEP80, HEL112, 多聚泛肽, 核糖体蛋白S27a, RPS27A, S27A, UBA80, UBC, UBCEP1, UBCEP80
缓冲液 :
冻干来自a溶液在去离子水
共轭标签 :
未共轭
all available conjugate :
未共轭
纯度 :
>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain
物种 :
人类
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
理论上的分子量 :
17 kDa (Ub2), 26 kDa (Ub3), 34 kDa (Ub4), 43 kDa (Ub5), 52 kDa (Ub6), and 60 kDa (Ub7)
功能细节 :
Ubiquitin chains vary in length, linkage, and function. K48-linked Poly-Ub WT Chains (Ub2-7) are ideal for investigating Ubiquitin-binding proteins and as substrates for Ubiquitin-specific isopeptidases. Reaction conditions will need to be optimized for each specific application. IMPORTANT: Heating this product in SDS-PAGE buffer or terminating reactions containing this product with heated SDS-PAGE buffer could lead to unexpected, high apparent molecular weight banding or smearing on gels that is not representative of product purity. For optimal results, we recommend incubation in SDS-PAGE buffer + DTT at <40 °C for 20 minutes prior to gel electrophoresis.
accessionNumbers :
P0CG47
应用 :
酶活性
来源 :
E. coli-derived Recombinant Human Poly-Ub WT Chains (2-7) (K48-linked), CF
美元 :
235
Jul-22 :
254美元
sizes available :
100微克
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.