产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
Recombinant Human Poly-Ub WT Chains (2-7) (K63-linked), CF
目录 :
UC-330-100
规格 :
100微克
价格 :
254美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 8
参考文献
Hage A, Bharaj P, van Tol S, Giraldo M, Gonzalez Orozco M, Valerdi K, et al. The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity. Cell Rep. 2022;38:110434 pubmed 出版商
Chai Q, Wang X, Qiang L, Zhang Y, Ge P, Lu Z, et al. A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy. Nat Commun. 2019;10:1973 pubmed 出版商
Brickner J, Soll J, Lombardi P, Vågbø C, Mudge M, Oyeniran C, et al. A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair. Nature. 2017;551:389-393 pubmed 出版商
Xu P, Hankins H, MacDonald C, Erlinger S, Frazier M, Diab N, et al. COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal. elife. 2017;6: pubmed 出版商
Lu K, den Brave F, Jentsch S. Receptor oligomerization guides pathway choice between proteasomal and autophagic degradation. Nat Cell Biol. 2017;19:732-739 pubmed 出版商
Luijsterburg M, Typas D, Caron M, Wiegant W, van den Heuvel D, Boonen R, et al. A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation. elife. 2017;6: pubmed 出版商
Zhong H, Wang D, Fang L, Zhang H, Luo R, Shang M, et al. Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling. PLoS ONE. 2013;8:e80976 pubmed 出版商
Hu X, Paul A, Wang B. Rap80 protein recruitment to DNA double-strand breaks requires binding to both small ubiquitin-like modifier (SUMO) and ubiquitin conjugates. J Biol Chem. 2012;287:25510-9 pubmed 出版商
产品信息
品牌 :
R&D Systems
master code :
UC-330
SKU号 :
UC-330-100
产品名称 :
Recombinant Human Poly-Ub WT Chains (2-7) (K63-linked), CF
单位尺寸 :
100微克
描述 :
The AQUApure Tetra-Ub Chains (K11-linked) Protein, CF from R&D Systems is derived from E. coli. The AQUApure Tetra-Ub Chains (K11-linked) Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
Poly-Ubiquitin
类别 :
蛋白和酶
别名 :
CEP80, HEL112, 多聚泛肽, 核糖体蛋白S27a, RPS27A, S27A, UBA80, UBC, UBCEP1, UBCEP80
缓冲液 :
冻干来自a溶液在去离子水
共轭标签 :
未共轭
all available conjugate :
未共轭
纯度 :
>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain
物种 :
人类
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
理论上的分子量 :
17 kDa (Ub2), 26 kDa (Ub3), 34 kDa (Ub4), 43 kDa (Ub5), 52 kDa (Ub6), and 60 kDa (Ub7)
功能细节 :
Ubiquitin chains vary in length, linkage, and function. K63-linked Poly-Ub WT Chains (Ub2-7) are ideal for investigating Ubiquitin-binding proteins and as substrates for Ubiquitin-specific isopeptidases. Reaction conditions will need to be optimized for each specific application. IMPORTANT: Heating this product in SDS-PAGE buffer or terminating reactions containing this product with heated SDS-PAGE buffer could lead to unexpected, high apparent molecular weight banding or smearing on gels that is not representative of product purity. For optimal results, we recommend incubation in SDS-PAGE buffer + DTT at <40 °C for 20 minutes prior to gel electrophoresis.
accessionNumbers :
P0CG47
应用 :
酶活性
来源 :
E. coli-derived Recombinant Human Poly-Ub WT Chains (2-7) (K63-linked), CF
美元 :
235
Jul-22 :
254美元
sizes available :
100微克
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.