产品简要
信息索取 :
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
人类/小鼠/大鼠HIF-1甲抗体
目录 :
MAB1536
规格 :
100微克
价格 :
269美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
241809
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫沉淀
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 26
已发表的文献中的应用方法／种属／稀释度参考文献
  • 免疫印迹; 人类; 1:1000; 图 7a
Sharma B, Kolhe R, Black S, Keller J, Mivechi N, Satyanarayana A. Inhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells. FASEB J. 2016;30:262-75 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Ferreira J, Soares A, Ramalho J, Pereira P, Girao H. K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy. Sci Rep. 2015;5:10210 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Sun Y, George J, Rocha S. Dose-dependent effects of allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia. PLoS ONE. 2015;10:e0123649 pubmed 出版商
Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed 出版商
Gerriets V, Danzaki K, Kishton R, Eisner W, Nichols A, Saucillo D, et al. Leptin directly promotes T-cell glycolytic metabolism to drive effector T-cell differentiation in a mouse model of autoimmunity. Eur J Immunol. 2016;46:1970-83 pubmed 出版商
Oh E, Kim J, Kim J, Kim S, Lee J, Hong S, et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun. 2016;7:13593 pubmed 出版商
Suyama K, Silagi E, Choi H, Sakabe K, Mochida J, Shapiro I, et al. Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget. 2016;7:23056-71 pubmed 出版商
Orr A, Vargas L, Turk C, Baaten J, Matzen J, Dardov V, et al. Suppressors of superoxide production from mitochondrial complex III. Nat Chem Biol. 2015;11:834-6 pubmed 出版商
Fischer C, Leithner K, Wohlkoenig C, Quehenberger F, Bertsch A, Olschewski A, et al. Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization. Mol Cancer. 2015;14:4 pubmed 出版商
Fujita N, Hirose Y, Tran C, Chiba K, Miyamoto T, Toyama Y, et al. HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells. FASEB J. 2014;28:2455-65 pubmed 出版商
Bruzzese L, Fromonot J, By Y, Durand-Gorde J, Condo J, Kipson N, et al. NF-κB enhances hypoxia-driven T-cell immunosuppression via upregulation of adenosine A(2A) receptors. Cell Signal. 2014;26:1060-7 pubmed 出版商
Melvin A, Mudie S, Rocha S. The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH. Mol Biol Cell. 2011;22:4171-81 pubmed 出版商
Naranjo-Suarez S, Carlson B, Tsuji P, Yoo M, Gladyshev V, Hatfield D. HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia. PLoS ONE. 2012;7:e30470 pubmed 出版商
Zahm A, Bucaro M, Srinivas V, Shapiro I, Adams C. Oxygen tension regulates preosteocyte maturation and mineralization. Bone. 2008;43:25-31 pubmed 出版商
van Uden P, Kenneth N, Webster R, Müller H, Mudie S, Rocha S. Evolutionary conserved regulation of HIF-1β by NF-κB. PLoS Genet. 2011;7:e1001285 pubmed 出版商
Hickey M, Richardson T, Wang T, Mosqueira M, Arguiri E, Yu H, et al. The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice. J Clin Invest. 2010;120:827-39 pubmed 出版商
Zhou J, Joplin D, Cross J, Templeton D. Sulforaphane inhibits prostaglandin E2 synthesis by suppressing microsomal prostaglandin E synthase 1. PLoS ONE. 2012;7:e49744 pubmed 出版商
Newton I, Kenneth N, Appleton P, Näthke I, Rocha S. Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection. Mol Biol Cell. 2010;21:3630-8 pubmed 出版商
Zhdanov A, Dmitriev R, Papkovsky D. Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling. Biosci Rep. 2012;32:587-95 pubmed 出版商
Risbud M, Guttapalli A, Stokes D, Hawkins D, Danielson K, Schaer T, et al. Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment. J Cell Biochem. 2006;98:152-9 pubmed
Liu H, Xue W, Ge G, Luo X, Li Y, Xiang H, et al. Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1α in MSCs. Biochem Biophys Res Commun. 2010;401:509-15 pubmed 出版商
Kim H, Jeong J, Kim S, Park S, Chae H, Lee Y. Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway. Sci Rep. 2013;3:1142 pubmed 出版商
Monnier Y, Farmer P, Bieler G, Imaizumi N, Sengstag T, Alghisi G, et al. CYR61 and alphaVbeta5 integrin cooperate to promote invasion and metastasis of tumors growing in preirradiated stroma. Cancer Res. 2008;68:7323-31 pubmed 出版商
Bett J, Ibrahim A, Garg A, Kelly V, Pedrioli P, Rocha S, et al. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Biochem J. 2013;451:185-94 pubmed 出版商
Taniguchi H, Mohri I, Okabe-Arahori H, Kanekiyo T, Kagitani-Shimono K, Wada K, et al. Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains. Neurosci Lett. 2007;420:39-44 pubmed
Pescador N, Villar D, Cifuentes D, Garcia-Rocha M, Ortiz-Barahona A, Vazquez S, et al. Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1. PLoS ONE. 2010;5:e9644 pubmed 出版商
产品信息
SKU号 :
MAB1536
供货商号码 :
333
类别 :
一抗
单位尺寸 :
100微克
产品名称 :
人类/小鼠/大鼠HIF-1甲抗体
别名 :
ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF 1A, HIF1 alpha, HIF-1 alpha, HIF1A, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcriptionfactor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1HIF1-ALPHA, PAS domain-containing protein 8, PASD8alpha subunit (basic helix-loop-helix transcriptionfactor)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
241809
浓度 :
LYOPH
共轭标签 :
未共轭
dilution :
Western Blot 1 ug/mL, Simple Western 1 ug/mL, Immunoprecipitation 1-3 ug/500 ug cell lysate
宿主 :
小鼠
免疫原 :
E. coli -derived recombinant human HIF-1 alpha , Arg575-Asn826, Accession # Q16665.1
抗体亚型 :
IgG1
防腐剂 :
无防腐剂
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类, 小鼠, 大鼠
特异性 :
Detects human, mouse, and rat HIF-1 alpha .
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
用途 :
In Simple Western only 10-15 uL of the recommended dilution is used per data point.
基因符号 :
缺氧诱导因子1A
species abr :
Hu, Mu, Rt
reconstitution instructions :
Reconstitute at 0.5 mg/mL in sterile PBS.
disabled countries :
例如, KP, KR, MX, MY, TR, TW, VN
catalog number base :
MAB1536
display host clonality :
小鼠单克隆
状态 :
活性的
Appended Catalog Number :
MAB1536
品牌 :
R&D Systems
top caption :
Detection of Human, Mouse, and Rat HIF-1 alpha by Western Blot. Western blot shows lysates of MCF-7 human breast cancer cell line, Balb-3T3 mouse embryonic fibroblast cell line, and PC-12 rat adrenal pheochromocytoma cell line untreated (-) or treated (+) with 150 µM CoCl2 for 8 hours. PVDF membrane was probed with 1 µg/mL of Human/Mouse/Rat HIF-1 alpha Monoclonal Antibody, followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007 ). A specific band was detected for HIF-1 alpha at approximately 120 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .
靶标 :
HIF-1甲
accessionNumbers :
Q16665.1
应用 :
Western Blot, Simple Western, Immunoprecipitation
产品关键词 :
MAB1536, h/m/rHIF-1a MAb Cl 241809, Mouse Anti-Human/Mouse/Rat HIF-1 alpha Monoclonal Antibody, Anti-HIF-1 alpha, Mouse Anti Human/Mouse/Rat HIF-1 alpha Monoclonal Antibody, Anti-hHIF-1 alpha, Anti-mHIF-1 alpha, Anti-rHIF-1 alpha, SC-10790 X, sc-8711
美元 :
269美元
GBP :
203
欧元 :
263
CAN :
296
SEK :
2702
NOK :
2525
CHF :
415
DKK :
2094
applications abr :
WB, Simple Western, IP
default size :
TRUE
top image title :
Detection of Human, Mouse, and Rat HIF-1 alpha by Western Blot.
toxin :
FALSE
controlled canada :
FALSE
controlled uk :
FALSE
controlled usa :
FALSE
nfs usa :
FALSE
铅时间天 :
3
PubMedIds :
16408279, 17499437, 18485858, 18794119, 20197624, 20869949, 21298084, 24486403, 24558194, 25608569, 25830774, 27222115, 27966538
铅时间描述 :
1-3 Business Days
CZK :
7101
HUF :
82582
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
www.rndsystemschina.com.cn
21 52380373
公司总部: 美国