蛋白

Tau-352 protein

009-001-T73

50微克

379.00美元

Tau-352 recombinant protein - 009-001-T73

Tau-352 protein

Tau-352 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. Tau-352 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~49kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

See application note.

0.2微克/微升

(None)

50微克

微克

User Optimized

Expiration date is one (1) year from date of opening.

MAPT

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

干冰

Liquid (sterile filtered)

Recombinant full-length human tag-free Tau-352 was expressed in E. coli cells. The purity was determined to be >90% by densitometry.

人类

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Tau-A, (N0R3), MAPT, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, FLJ31424, MGC138549, Microtubule-associated protein tau

Tau-352 is a member of the Tau family of proteins which function to stabilize the microtubules by binding to them. Tau proteins are subject to phosphorylation and this phenomenon regulates the association of the Tau protein with the microtubules (1). Deposits of Alzheimer's disease AD-associated proteins, such as hyperphosphorylated Tau, as well as other shared misfolded proteins, such as, β-amyloid precursor protein (βAPP), ubiquitin, and various chaperones and protein kinases are thought to play a pathologic role in the cognitive decline and muscular failure. Malfunctioning of Tau proteins is associated with microtubules disintegration and collapsing of the neuronal transport system (2). Tau-352 Protein is ideal for investigators involved in Signaling Proteins, Tau Proteins, Invasion/Metastasis, Neurobiology, and p38 Pathway research.

1. Zilka, N., et al. Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo. FEBS Lett. 2006; 508: 3582-3588. 2. Rial, A. et al: Calcium Dyshomeostasis in β-Amyloid and Tau-bearing Skeletal Myotubes. J. Biol. Chem., 2004; 279: 3524-53532

No

重组蛋白

蛋白

No

免疫印迹

Kinase Assay-User Optimized

蛋白和肽

未共轭

379.00美元

P10636-2