抗体

p16抗体

100-401-170

100微升

多克隆

domestic rabbit

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀

抗p16(兔)抗体-100-401

p16抗体

This product was assayed by immunoblot and found to be reactive against p16 from cell lysates and E.coli produced fusion proteins at a dilution of 1:1000 followed by reaction with Peroxidase conjugated Affinity Purified anti-Rabbit IgG [H&L] (Goat) (code #611-1302).  Anti-p16 is suitable for the detection by immunoblot of human p16.  This antisera is also suitable for immunoprecipitation of in vitro translated protein and cell lysates (Saos-2, 3T3-L1 weakly) and will co-precipitate associated proteins including p15 and potentially p15.5. This product was tested in IHC.

多克隆

85毫克/毫升

by Refractometry

(None)

100微升

微升

1:5, 000 - 1:20, 000

1:500

1:100

1:500 - 1:5, 000

Expiration date is one (1) year from date of opening.

抗血清

CDKN2A

兔

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

human p16 protein (missing the first 7 amino acids)

干冰

Liquid (sterile filtered)

0.01%(w/v)叠氮化钠

This product was prepared from monospecific antiserum by delipidation and defibrination.  Antiserum will specifically react with a p16 protein from human  tissue.  Cross reactivity may occur with p15 when immunoprecipitating in vitro translated product but not in immunoblots.  Potentially cross reacts with p15.5.

人类

Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

rabbit anti-p16 Antibody, Cyclin-dependent kinase inhibitor 2A isoforms 1/2/, Cyclin-dependent kinase 4 inhibitor A, CDK4I, p16-INK4a, p16INK4A, p16-INK4, Multiple tumor suppressor 1, MTS-1, CDKN2, MTS1

人类

The gene for CDK2NA generates several transcripts/proteins which differ from each other in their first exons. Three of these transcripts are generated by alternative splicing (isoform 1 a.k.a p16INK4A, isoform 2 and isoform 3 a.k.a p12), two of which are known to function as inhibitors of CDK4 kinase. One other transcript that is generated from this gene contains an alternate reading frame (ARF), with the first exon located 20kb upstream of the remainder of the gene (isoform 4 a.k.a. p14ARF, p19ARF, ARF). In spite of the structural and some functional differences, all the proteins encoded by the CDKN2A gene are involved in cell cycle G1 control.

天然蛋白

No

No

酶联免疫吸附测定, 免疫组化, 免疫沉淀, 免疫印迹

User Optimized

一抗

未共轭

P42771

AAH15960.3

抗p16抗体-免疫组化