抗体

IRAK抗体[8F1A7]

200-301-BZ2

100微克

单克隆

小鼠

未共轭

[8F1A7]

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化

抗IRAK(小鼠)抗体-200-301

IRAK抗体[8F1A7]

Anti-IRAK Antibody has been tested for use in ELISA, Western Blotting, and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 77 kDa in Western Blots of specific cell lysates and tissues. WB validated in mouse samples and IHC validates in rat samples. All other applications and species not yet tested.

0.01 M钠磷酸盐, 0.25 M氯化钠, pH值7.2

单克隆

[8F1A7]

1毫克/毫升

by UV absorbance at 280 nm

(None)

100微克

微克

1:10,000-1:20,000

5微克/毫升

1-2微克/毫升

Expiration date is one (1) year from date of opening.

IgG1

IRAK1

小鼠

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Anti-IRAK antibody was produced in mice by repeated immunizations with recombinant protein corresponding to amino acids 618 - 712 of human IRAK.

干冰

Liquid (sterile filtered)

0.02%(w/v)叠氮化钠

Anti-IRAK Monoclonal Antibody was Protein A purified from monospecific antiserum by immunoaffinity purification. Cross reactivity with IRAK [8F1A7] from other sources has not been determined.

人类, 小鼠

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

IgG1

IRAK Antibody [8F1A7] , IRAK, pelle

人类

Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).

多肽

No

No

内部

酶联免疫吸附测定, 免疫组化, 免疫印迹

一抗

未共轭

P51617

P51617

Immunohistochemistry of IRAK Antibody