产品简要
公司名称 :
Rockland Immunochemicals
产品类型 :
抗体
产品名称 :
IKB甲抗体
目录 :
200-301-H80
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6A920
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫沉淀, 流式细胞仪
更多信息或购买 :
产品信息
目录号 :
200-301-H80
名称 :
抗IKBα(小鼠)单克隆抗体-200-301
显示名称 :
IKB甲抗体
应用注释 :
Anti-IkB alpha antibody is suitable for use in Flow (I), IHC (p), IP and WB. Expect a band approximately 35kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
缓冲液 :
0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2
克隆性 :
单克隆
克隆编号 :
6A920
浓度值 :
1.0毫克/毫升
浓度定义 :
by UV absorbance at 280 nm
共轭 :
(None)
规格 :
100微克
默认单元 :
微克
流式细胞仪稀释浓度 :
0.25-1微克/10^6细胞
免疫沉淀稀释度 :
1微克/毫升
免疫印迹稀释浓度 :
1-2微克/毫升
有效期 :
Expiration date is one (1) year from date of opening.
格式 :
IgG1
基因名称 :
NFKBIA
宿主动物 :
小鼠
一般免责声明 :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
免疫原 :
IkB alpha Antibody was produced in mice prepared by repeated immunizations of recombinant protein corresponding to internal amino acids in the human IkB alpha protein.
包装类型 :
干冰
物理状态 :
液体
防腐剂 :
0.05%(w/v)叠氮化钠
纯度和特异性 :
Anti-IkBα Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with IkBα from Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-IkBα from other sources has not been determined.
物种活性 :
人类, 小鼠
稳定剂 :
0.05% BSA
储存 :
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
子种类 :
IgG1 kappa
同义词 :
IKBA, MAD3, NFKBI, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3
靶物种 :
人类
背景 :
Anti-IkB alpha detects human IkB alpha. NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. Synthesis of IkBa is autoregulated. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g. External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first gene induced following NF-kB activation is IkBa. Anti-IkB alpha antibody is ideal for investigators involved in NFkappaB, kinase and phosphatase research.
免疫原类型 :
重组蛋白
低内毒素 :
No
样品尺寸 :
No
靶活性结构域 :
内部
应用文本 :
流式细胞仪, 免疫沉淀, 免疫印迹
其他 :
User Optimized
类别 :
一抗
共轭名称 :
未共轭
UniProt数据库 :
P25963
NCBI :
NP_065390.1
最初图像名称 :
IkB alpha Western Blot
更多信息或购买 :
公司信息
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
orders@rockland-inc.com
https://www.rockland.com/
800-656-7625
公司总部: 美国
Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部,为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立,利用In vitro及In vivo方法制备并纯化单抗及多抗,这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究:Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。