抗体

p73抗体

200-301-I00

100微克

单克隆

小鼠

未共轭

5B429

免疫印迹, 免疫组化

抗p73(小鼠)单克隆抗体-200-301

p73抗体

Anti-p73 Antibody is suitable for use in ChIP, IF/ICC, IHC (frozen), IHC (p), IP and WB. Expect a band approximately 70kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2

单克隆

5B429

1.0毫克/毫升

by UV absorbance at 280 nm

(None)

100微克

微克

5-15微克/毫升

2微克/毫升

Expiration date is one (1) year from date of opening.

IgG1

TP73

小鼠

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

p73 Antibody was produced in mice prepared by repeated immunizations with full-length human p73 protein.

干冰

液体

0.05%(w/v)叠氮化钠

Anti-p73 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-p73 from Human and Mouse based on 100% homology with the immunizing sequence. It does not cross react with p53. Cross-reactivity with Anti-p73 from other sources has not been determined.

人类

0.05% BSA

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

IgG1 kappa

P73, Tumor protein p73, p53-like transcription factor, p53-related protein

人类

Anti-p73 detects human p73. NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. Synthesis of IkBa is autoregulated. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g. External stimuli such as tumor necrosis factor or other cytokines initiates a signal transduction cascade that leads to the activation of IkB-kinase complex that specifically phosphorylates IkBa on Serine-32 and Serine-36. Phosphorylation of these sites leads to ubiquitination of IkBa and subsequent degradation by the 26 S proteasome. Degradation of IkBa results in unmasking of the nuclear localization signal of NF-kB dimers, which subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first gene induced following NF-kB activation is IkBa. Anti-p73 antibody is ideal for investigators involved in NFkappaB, kinase and phosphatse research.

多肽

No

No

免疫组化, 免疫印迹

一抗

未共轭

O15350

NP_001119712.1

p73免疫印迹