产品简要
公司名称 :
Rockland Immunochemicals
产品类型 :
抗体
产品名称 :
CD11c荧光素抗体
目录 :
200-302-N63
规格 :
500微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
3.9
反应物种 :
人类
应用 :
免疫组化, 流式细胞仪
更多信息或购买 :
产品信息
目录号 :
200-302-N63
名称 :
抗CD11c(小鼠)荧光素共轭标签单克隆抗体-200-302
显示名称 :
CD11c荧光素抗体
应用注释 :
Anti-CD11c is useful for Flow Cytometry and Immunohistochemistry. Researchers should determine optimal titers for applications that are not stated.
缓冲液 :
0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2
克隆性 :
单克隆
克隆编号 :
3.9
浓度定义 :
Sufficient to run approximately 100 tests
共轭 :
异硫氰酸荧光素
规格 :
500微升
默认单元 :
微升
流式细胞仪稀释浓度 :
5 ul/1x10e6 cells or 100µL of whole blood
荧光蛋白值 :
4-6
免疫组化稀释度 :
User Optimized
有效期 :
Expiration date is six (6) months from date of opening.
格式 :
IgG1
基因名称 :
ITGAX
宿主动物 :
小鼠
一般免责声明 :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
免疫原 :
Anti-CD11c Antibody (Monoclonal) was produced by repeated immunizations with CD11c antigen.
包装类型 :
Wet Ice
物理状态 :
Liquid (sterile filtered)
防腐剂 :
0.09%(w/v)叠氮化钠
纯度和特异性 :
Fluorescein conjugated CD11c Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD11c. Reactivity is observed against human CD11c, Chimpanzee, Baboon, African Green, Cynomolgus, Rhesus, and Squirrel Monkey. Cross reactivity with CD11c from other sources has not been tested. Anti-CD11c is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC.
物种活性 :
人类
稳定剂 :
0.2% BSA(w/v)
储存 :
Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.
子种类 :
IgG1 kappa
同义词 :
Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150 95, CD11c
靶物种 :
人类
背景 :
CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTThe 3.9 antibody reacts with human CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.
低内毒素 :
No
样品尺寸 :
No
应用文本 :
流式细胞仪, 免疫组化
类别 :
一抗
共轭名称 :
荧光素(异硫氰酸荧光素)
UniProt数据库 :
P20702
NCBI :
NP_000878.2
最初图像名称 :
流式细胞仪-小鼠抗CD11c异硫氰酸荧光素
更多信息或购买 :
公司信息
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
orders@rockland-inc.com
https://www.rockland.com/
800-656-7625
公司总部: 美国
Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部,为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立,利用In vitro及In vivo方法制备并纯化单抗及多抗,这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究:Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。