产品简要
公司名称 :
Rockland Immunochemicals
产品类型 :
抗体
产品名称 :
CD28藻红蛋白抗体
目录 :
200-308-N66
规格 :
500微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
RPE
克隆名称 :
CD28.2
反应物种 :
人类
应用 :
免疫组化, 免疫沉淀, 流式细胞仪
更多信息或购买 :
产品信息
目录号 :
200-308-N66
名称 :
抗CD28(小鼠)藻红蛋白共轭标签单克隆抗体-200-308
显示名称 :
CD28藻红蛋白抗体
应用注释 :
Anti-CD28 is useful for Flow Cytometry, Immunoprecipitation, and Immunohistochemistry. Researchers should determine optimal titers for applications that are not stated.
缓冲液 :
0.01 M钠磷酸盐, 0.15 M氯化钠, pH值7.2
克隆性 :
单克隆
克隆编号 :
CD28.2
浓度值 :
0.05毫克/毫升
浓度定义 :
Sufficient to run approximately 100 tests
共轭 :
RPE
规格 :
500微升
默认单元 :
微升
流式细胞仪稀释浓度 :
5µL/test/1x10e5 to 1x10e8 cells
荧光蛋白值 :
1-2
免疫组化稀释度 :
User Optimized
免疫沉淀稀释度 :
User Optimized
有效期 :
Expiration date is six (6) months from date of opening.
格式 :
IgG1
基因名称 :
CD28
宿主动物 :
小鼠
一般免责声明 :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
免疫原 :
Anti-CD28 Antibody (Monoclonal) was produced by repeated immunizations with CD28 antigen.
包装类型 :
Wet Ice
物理状态 :
Liquid (sterile filtered)
防腐剂 :
0.09%(w/v)叠氮化钠
纯度和特异性 :
Phycoerythrin conjugated CD28 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD28. Reactivity is observed against human CD28, Baboon, Chimpanzee, Cynomolgus, and Rhesus. Cross reactivity with CD28 from other sources has not been tested. Anti-CD28 is conjugated with PE under optimal conditions and the solution is free of unconjugated PE.
物种活性 :
人类
稳定剂 :
0.1% 明胶
储存 :
Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
子种类 :
IgG1 kappa
同义词 :
T细胞表面的糖蛋白CD28, TP44, CD28
靶物种 :
人类
背景 :
The CD28 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA. The CD28.2 antibody may be used as a phenotypic marker for human CD28, expressed on all CD4+ T cells and CD8+ T cells, and is widely used as a reagent for activation of the CD28 receptor in vitro and in vivo.
低内毒素 :
No
样品尺寸 :
No
应用文本 :
流式细胞仪, 免疫组化, 免疫沉淀
类别 :
一抗
共轭名称 :
R藻红蛋白(RPE)
UniProt数据库 :
P10747
NCBI :
NP_001230006.1
最初图像名称 :
流式细胞仪-小鼠抗CD28 PE
更多信息或购买 :
公司信息
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
orders@rockland-inc.com
https://www.rockland.com/
800-656-7625
公司总部: 美国
Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部,为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立,利用In vitro及In vivo方法制备并纯化单抗及多抗,这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究:Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。