抗体

ARMER抗体

200-401-Y61

100微克

多克隆

domestic rabbit

未共轭

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化

抗ARMER(兔)抗体-200-401

ARMER抗体

Anti-ARMER Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 23 kDa in Western Blots of specific cell lysates and tissues.

0.01 M钠磷酸盐, 0.25 M氯化钠, pH值7.2

多克隆

1毫克/毫升

by UV absorbance at 280 nm

(None)

100微克

微克

1:5000-1:20,000

2微克/毫升

2微克/毫升

0.5-2微克/毫升

Expiration date is one (1) year from date of opening.

IgG

ARL6IP1

兔

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Anti-ARMER antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 15 amino acids near the C-terminus of human ARMER.

干冰

Liquid (sterile filtered)

0.02%(w/v)叠氮化钠

Anti-ARMER Antibody is purified by ion exchange chromatography. Cross reactivity with ARMER from other sources has not been determined.

人类, 小鼠

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

ARMER Antibody, AIP1, ARMER, SPG61, ARL6IP, KIAA0069, ADP-ribosylation factor-like protein 6-interacting protein 1, ARL-6-interacting protein 1

人类

Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA. Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress. Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity, although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

多肽

No

No

C末端

酶联免疫吸附测定, 免疫组化, IF显微镜, 免疫印迹

一抗

未共轭

Q15041

Q15041

Immunofluorescence of ARMER Antibody