产品简要
公司名称 :
Rockland Immunochemicals
产品类型 :
抗体
产品名称 :
胶质纤维酸性蛋白(GFAP)抗体
目录 :
200-901-D60
规格 :
100微升
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
大鼠,
应用 :
免疫印迹
更多信息或购买 :
产品信息
目录号 :
200-901-D60
名称 :
抗胶质纤维酸性蛋白(GFAP)(鸡)抗体-200-901
显示名称 :
胶质纤维酸性蛋白(GFAP)抗体
应用注释 :
Anti-Glial Fibrillary Acidic Protein (Chicken) antibody is suitable for use in Western Blotting and IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 50 kDa in size corresponding to the GFAP proteins in the appropriate cell lysate or extract. A lower band at ~45kDa is a proteolytic fragment derived from the GFAP molecule.
缓冲液 :
0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2
克隆性 :
多克隆
浓度值 :
Titrated value sufficient to run approximately 10 mini blots.
共轭 :
(None)
规格 :
100微升
默认单元 :
微升
免疫荧光显微镜稀释浓度 :
1:1000
免疫印迹稀释浓度 :
1:10000
有效期 :
Expiration date is one (1) year from date of opening.
格式 :
IgG
基因名称 :
GFAP
宿主动物 :
一般免责声明 :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
免疫原 :
Anti-GFAP Antibody was produced by repeated immunizations with recombinant and extensively purified bovine GFAP.
包装类型 :
干冰
物理状态 :
液体
防腐剂 :
0.01%(w/v)叠氮化钠
纯度和特异性 :
Anti-GFAP Antibody is directed against bovine GFAP. The antibody is a total IgY fraction. Expect reactivity with the following species based on sequence homology: human, mouse, rat. Cross reactivity with GFAP from other species has not been determined.
物种活性 :
大鼠
储存 :
Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
同义词 :
gfapl, DKFZp459C0729, MGC139638, FLJ45472, AI836096, cb345. Glial fibrillary acidic protein, GFAP antibody, neuroscience antibodies
靶物种 :
背景 :
GFAP Antibody detects GFAP. Glial Fibrillary Acidic Protein (GFAP) was discovered by Amico Bignami and co-workers as a major fibrous protein of multiple sclerosis plaques. It was subsequently found to be a member of the 10nm or intermediate filament (IF) family, specifically the IF family Class III, which also includes peripherin, desmin and vimentin. GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the CNS, in satellite cells, peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition, neural stem cells frequently strongly express GFAP. Point mutations in the protein coding region of the GFAP gene lead to Alexander disease which is characterized by the presence of abnormal astrocytes containing GFAP protein aggregates known as Rosenthal fibers. Therefore, GFAP antibody is ideal for investigators involved in neuropathologic diseases and more generally in Neuroscience.
免疫原类型 :
重组蛋白
低内毒素 :
No
样品尺寸 :
No
应用文本 :
IF显微镜, 免疫印迹
类别 :
一抗
共轭名称 :
未共轭
UniProt数据库 :
Q28115
最初图像名称 :
Immunofluorescence Microscopy of Anti-Glial Fibrillary Acidic Protein (GFAP) (Chicken) Antibody
更多信息或购买 :
公司信息
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
orders@rockland-inc.com
https://www.rockland.com/
800-656-7625
公司总部: 美国
Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部,为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立,利用In vitro及In vivo方法制备并纯化单抗及多抗,这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究:Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。