产品简要
公司名称 :
Rockland Immunochemicals
产品类型 :
抗体
产品名称 :
载脂蛋白b抗体
目录 :
600-101-111
规格 :
1
价格 :
https://www.rockland.com/search/?searchString=600-101-111
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀
更多信息或购买 :
文章摘录数: 3
参考文献
Morishita H, Zhao Y, Tamura N, Nishimura T, Kanda Y, Sakamaki Y, et al. A critical role of VMP1 in lipoprotein secretion. elife. 2019;8: pubmed 出版商
Sołtysik K, Ohsaki Y, Tatematsu T, Cheng J, Fujimoto T. Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis. Nat Commun. 2019;10:473 pubmed 出版商
Lu R, Yuan T, Wang Y, Zhang T, Yuan Y, Wu D, et al. Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7. EBioMedicine. 2018;36:29-38 pubmed 出版商
产品信息
目录号 :
600-101-111
名称 :
抗载脂蛋白b(山羊)抗体-600-101
显示名称 :
载脂蛋白b抗体
应用注释 :
Anti-apoLipoprotein antibodies have been used for indirect trapping ELISA for quantitation of antigen in serum using a standard curve, for immunoprecipitation and for western blotting for highly sensitive qualitative analysis.
缓冲液 :
0.125 M钠硼酸盐, 0.075 M氯化钠, 0.005 M乙二胺四乙酸, pH值8.0
克隆性 :
多克隆
浓度值 :
1.0毫克/毫升
浓度定义 :
by UV absorbance at 280 nm
共轭 :
(None)
规格 :
1
默认单元 :
毫克
ELISA稀释浓度 :
1:2, 000 - 1:10, 000
免疫组化稀释度 :
1:50 - 1:500
免疫荧光显微镜稀释浓度 :
User Optimized
免疫沉淀稀释度 :
1:100
免疫印迹稀释浓度 :
1:200 - 1:1, 000
有效期 :
Expiration date is one (1) year from date of receipt.
格式 :
IgG
基因名称 :
载脂蛋白B
宿主动物 :
山羊
一般免责声明 :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
免疫原 :
apoLipoprotein Type B was isolated from human plasma by density gradient centrifugation followed by HPLC purification.
包装类型 :
Wet Ice
物理状态 :
Liquid (sterile filtered)
防腐剂 :
0.01%(w/v)叠氮化钠
纯度和特异性 :
This product has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other apoLipoproteins and human serum proteins to remove any unwanted specificities.  Typically less than 1% cross reactivity against other types of apoLipoprotein was detected by ELISA against purified standards.  This antibody reacts with human apoLipoprotein B and has negligible cross-reactivity with Type A-I, A-II, C-I, C-II, C-III, E and J apoLipoproteins.  Specific cross reaction of anti-apoLipoprotein antibodies with antigens from other species has not been determined.  Non-specific cross reaction of anti-apoLipoprotein antibodies with other human serum proteins is negligible.
物种活性 :
人类
Suggested Applications :
ELISA; IF; IHC; IP; Multiplex; WB
储存 :
Store vial at 4° C prior to opening.   This product is stable 4° C as an undiluted liquid.  Dilute only prior to immediate use.  For extended storage mix with an equal volume of glycerol, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing.
同义词 :
山羊抗载脂蛋白b抗体, 载脂蛋白B-100, 载脂蛋白B-48, 载脂蛋白B蛋白抗体, 载脂蛋白b 100抗体, 载脂蛋白b 48抗体, 载脂蛋白b抗体, FLDB抗体
靶物种 :
人类
背景 :
Anti Apolipoprotein B antibody recognizes the gene product of APOB that is the primary apolipoprotein of low-density lipoproteins, which is responsible for carrying cholesterol to tissues. While it is unclear exactly what functional role APOB plays in LDL, it is the primary apolipoprotein component and is absolutely required for its formation. What is clear is that the APOB on the LDL particle acts as a ligand for LDL receptors in various cells throughout the body. Through a mechanism that is not fully understood, high levels of APOB can lead to plaques that cause vascular disease (atherosclerosis), leading to heart disease. There is considerable evidence that levels of APOB are a better indicator of heart disease and cardiovascular risk than total cholesterol or LDL. However, primarily for historic reasons, cholesterol, and more specifically, LDL-cholesterol, remains the primary lipid test for the risk factor of atherosclerosis.
免疫原类型 :
天然蛋白
低内毒素 :
No
样品尺寸 :
No
应用文本 :
酶联免疫吸附测定, 免疫组化, IF显微镜, 免疫沉淀, 免疫印迹
其他 :
User Optimized
类别 :
一抗
共轭名称 :
未共轭
2024价格 :
$1,285.00
UniProt数据库 :
Q7Z7Q0
NCBI :
AAH51278.1
最初图像名称 :
Western Blot of Anti-Apolipoprotein B
更多信息或购买 :
公司信息
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
orders@rockland-inc.com
https://www.rockland.com/
800-656-7625
公司总部: 美国
Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部,为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立,利用In vitro及In vivo方法制备并纯化单抗及多抗,这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究:Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。