抗体

FANCC抗体

600-401-672

100微克

369.00美元

多克隆

domestic rabbit

未共轭

免疫印迹, 酶联免疫吸附测定

抗人类FANCC(兔)抗体-600-401

FANCC抗体

This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 63 kDa in size corresponding to FANCC by western blotting in the appropriate human tissue.

0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2

多克隆

1.45毫克/毫升

by UV absorbance at 280 nm

(None)

100微克

微克

1:20, 000 - 1:80, 000

1:1, 000 - 1:3, 000

Expiration date is one (1) year from date of opening.

IgG

FANCC

兔

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 80-115 of Human FANCC.

干冰

Liquid (sterile filtered)

0.01%(w/v)叠氮化钠

This affinity-purified antibody is directed against human FANCC protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest cross reactivity with FANCC protein from human and chimpanzee based on 100% homology with the immunizing sequence.  Reactivity against homologues from other sources is not known.

人类

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

rabbit anti-FANCC antibody, FANC-C, FANC C, FAC antibody, FACC antibody, Fanconi anemia group C protein, Fanconi anemia complementation group C antibody

人类

FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function.  FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM.  FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm.  This protein is ubiquitously expressed.  Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.

多肽

No

No

内部

酶联免疫吸附测定, 免疫印迹

User Optimized

一抗

未共轭

369.00美元

Q00597

56118236

抗FANCC抗体-免疫印迹