抗体

PARK-7抗体

600-401-691

100微克

369.00美元

多克隆

domestic rabbit

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化

抗人类PARK-7(兔)抗体-600-401

PARK-7抗体

This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 28 kDa in size corresponding to PARK7 by western blotting in the appropriate cell lysate or extract.

0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2

多克隆

1.3毫克/毫升

by UV absorbance at 280 nm

(None)

100微克

微克

1:10, 000 - 1:50, 000

2毫克/毫升-5微克/毫升

1:500 - 1:2, 000

Expiration date is one (1) year from date of opening.

IgG

PARK7

兔

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminus of Human PARK7 protein.

干冰

Liquid (sterile filtered)

0.01%(w/v)叠氮化钠

This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase. Reactivity occurs against human PARK7 protein.  BLAST analysis was used to determine that 100% homology with the immunizing peptide sequence is on record for this protein from human, chimpanzee, African green monkey, zebrafish and also for mutant/variant forms of human DJ-1 protein.  Cross reactivity with PARK7 from frog, mouse, rat, dog, chicken, Japanese rice fish and Atlantic salmon may also occur as the sequence varies by only one amino acid residue as indicated by BLAST analysis.  Reactivity with PARK7 protein from other sources is not known.

人类

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

rabbit anti-PARK7 antibody, PARK-7, PARK 7, Protein DJ-1, Parkinson disease protein 7, Parkinsonism-associated deglycase, DJ-1 mutant, oncogene DJ1, DJ-1 oncogene product

人类

The product of the PARK7 gene, known as PARK7, Parkinson disease (autosomal recessive, early onset) 7, DJ-1 mutant, and DJ-1 oncogene product, functions as a positive regulator of androgen receptor-dependent transcription.  PARK7 may also function as a redox-sensitive chaperone and as a sensor for oxidative stress and also has been reported to prevent aggregation of SNCA.   PARK7 protects neurons against oxidative stress and cell death and plays a role in fertilization. While PARK7 has no proteolytic activity, it does have a weak transforming activity.  PARK7 forms a homodimer and binds to DJBP and PIAS2.  PARK7 is part of a ternary complex containing PARK7, DJBP and AR and shows both a nuclear and cytoplasmic localization.  Diseases include Early onset autosomal recessive Parkinson Disease 7 and Parkinson Disease Juvenile Type 2.

多肽

No

No

C末端

酶联免疫吸附测定, 免疫组化, 免疫印迹

User Optimized

一抗

未共轭

369.00美元

Q99497

31543380

抗PARK7抗体-免疫组化