α微管蛋白抗体 | Rockland Immunochemicals 600-401-880 产品信息

产品简要

公司名称 :

Rockland Immunochemicals

产品类型 :

抗体

产品名称 :

α微管蛋白抗体

600-401-880

规格 :

200微克

克隆性 :

多克隆

宿主 :

domestic rabbit

共轭标签 :

未共轭

反应物种 :

人类

应用 :

免疫印迹, 酶联免疫吸附测定, 免疫组化

更多信息或购买 :

Rockland Immunochemicals 产品网页

文章摘录数: 10

参考文献
Xiao H, Wyler E, Milek M, Grewe B, Kirchner P, Ekici A, et al. CRNKL1 Is a Highly Selective Regulator of Intron-Retaining HIV-1 and Cellular mRNAs. MBio. 2021;12: pubmed 出版商
Garland W, Comet I, Wu M, Radzisheuskaya A, Rib L, Vitting Seerup K, et al. A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2. Cell Rep. 2019;29:1800-1811.e6 pubmed 出版商
Lloret Llinares M, Karadoulama E, Chen Y, Wojenski L, Villafano G, Bornholdt J, et al. The RNA exosome contributes to gene expression regulation during stem cell differentiation. Nucleic Acids Res. 2018;46:11502-11513 pubmed 出版商
Brown C, Dayan S, Wong S, Kaczmarek A, Hope C, Pederson S, et al. FOXP3 and miR-155 cooperate to control the invasive potential of human breast cancer cells by down regulating ZEB2 independently of ZEB1. Oncotarget. 2018;9:27708-27727 pubmed 出版商
Kim J, Kim Y. Effect of HIV-1 Tat on the formation of the mitotic spindle by interaction with ribosomal protein S3. Sci Rep. 2018;8:8680 pubmed 出版商
Kapadia M, Bijelić D, Zhao H, Ma D, Stojanovich L, Milosevic M, et al. Effects of sustained i.c.v. infusion of lupus CSF and autoantibodies on behavioral phenotype and neuronal calcium signaling. Acta Neuropathol Commun. 2017;5:70 pubmed 出版商
Ghosh A, Abdelwahab S, Reeber S, Reidel B, Marklew A, Garrison A, et al. Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression. Sci Rep. 2017;7:46239 pubmed 出版商
Liao H, Ren X, Peterson B, Marshak D, Yau K, Gamlin P, et al. Melanopsin-expressing ganglion cells on macaque and human retinas form two morphologically distinct populations. J Comp Neurol. 2016;524:2845-72 pubmed 出版商
Lloret Llinares M, Mapendano C, Martlev L, Lykke Andersen S, Jensen T. Relationships between PROMPT and gene expression. RNA Biol. 2016;13:6-14 pubmed 出版商
Li J, Dou X, Li S, Zhang X, Zeng Y, Song Z. Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation. Biochim Biophys Acta. 2015;1853:2929-36 pubmed 出版商

产品信息

目录号 :

600-401-880

名称 :

抗甲-微管蛋白(兔)抗体-600-401

显示名称 :

α微管蛋白抗体

应用注释 :

Anti-Tubulin Antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~50 kDa in size corresponding to alpha tubulin by western blotting in most cell lysates or extracts.

缓冲液 :

0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2

克隆性 :

多克隆

浓度值 :

1.1毫克/毫升

浓度定义 :

by UV absorbance at 280 nm

共轭 :

(None)

规格 :

200微克

默认单元 :

微克

ELISA稀释浓度 :

1:90,000

免疫组化稀释度 :

1:500 - 1:2, 000

免疫荧光显微镜稀释浓度 :

1:500 - 1:2, 000

免疫印迹稀释浓度 :

1:1, 000 - 1:5, 000

有效期 :

Expiration date is one (1) year from date of opening.

格式 :

IgG

基因名称 :

TUBA1B

宿主动物 :

兔

一般免责声明 :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

免疫原 :

Anti-Tubulin Loading Control Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-Terminal region near amino acids 425-451 of Human alpha Tubulin.

包装类型 :

干冰

物理状态 :

Liquid (sterile filtered)

防腐剂 :

0.01%(w/v)叠氮化钠

纯度和特异性 :

Anti-Tubulin Loading Control Antibody is directed against human alpha Tubulin protein. The Loading Control Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest that this antibody would react with alpha Tubulin from a wide range of organisms, including avian, mammalian aquatic, parasitic and alga sources based on 100% homology for the immunogen sequence. Cross reactivity will occur with all isoforms of alpha tubulin. Such broad reactivity makes this antibody useful as an excellent loading control.

物种活性 :

人类, 小鼠, 大鼠

储存 :

Store Anti-Tubulin Loading Control Antibody at -20° C prior to opening. Aliquot Loading Control Antibody contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge Tubulin Loading Control Antibody if not completely clear after standing at room temperature. This Control Antibody is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

同义词 :

rabbit anti-alpha-Tubulin Antibody, rabbit anti-α-tubulin antibody, Tubulin alpha-1B chain, Tubulin alpha-ubiquitous chain, Alpha-tubulin ubiquitous, Tubulin K-alpha-1, TUBA1B, tubulin loading control, Alpha-tubulin, Tubulin alpha-1A, TUBA1A, TUBA3, LIS3

靶物种 :

人类

背景 :

Tubulin Loading Control Antibody recognizes microtubules which are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein consisting of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. This antibody makes an excellent loading control. Anti-Alpha-tubulin antibody is ideal for investigators involved in cell cycle protein research.

免疫原类型 :

多肽

低内毒素 :

样品尺寸 :

靶活性结构域 :

C末端

应用文本 :

酶联免疫吸附测定, 免疫组化, IF显微镜, 免疫印迹

其他 :

User Optimized

类别 :

一抗

共轭名称 :

未共轭

UniProt数据库 :

P68363

NCBI :

17986283

最初图像名称 :

抗α微管蛋白-免疫印迹

更多信息或购买 :

Rockland Immunochemicals 产品网页

公司信息

Rockland Immunochemicals

321 Jones Blvd
Pottstown, PA 19464

orders@rockland-inc.com

https://www.rockland.com/

800-656-7625

公司总部: 美国

Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部，为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立，利用In vitro及In vivo方法制备并纯化单抗及多抗，这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究：Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。