抗体

细胞周期蛋白O抗体

600-401-AR9

100微克

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定

抗细胞周期蛋白O(兔)抗体-600-401

细胞周期蛋白O抗体

Anti-Cyclin O Antibody has been tested for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 39 kDa in Western Blots of specific cell lysates and tissues.

0.01 M钠磷酸盐, 0.25 M氯化钠, pH值7.2

多克隆

1毫克/毫升

by UV absorbance at 280 nm

(None)

100微克

微克

1:10,000-1:20,000

1-2微克/毫升

Expiration date is one (1) year from date of opening.

IgG

CCNO

兔

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Anti-Cyclin O antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide from near the internal region of human Cyclin O.

干冰

Liquid (sterile filtered)

0.02%(w/v)叠氮化钠

Anti-Cyclin O Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of Cyclin O are known to exist; this antibody will recognize both isoforms.

人类, 小鼠, 大鼠

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

细胞周期蛋白O抗体, CCNU, UDG2, 细胞周期蛋白O

人类

Cyclin O, also known as CCNO, has recently been identified as a Cdk1- and Cdk2-activating cyclin specific to apoptosis in lymphoid cells. Cyclin O binds to and activates Cdk2 in response to instrinsic apoptotic stimuli such as glucocorticoids or DNA-damaging agents. Supression of Cyclin O expression by shRNA leads to the inhibition of glucocorticoid and DNA-damage-induced apoptosis due to a failure of apical caspase activation while leaving the CD95 death receptor-mediated apoptosis intact. Note: this gene, which had a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase. A later publication identified this gene's product as a cyclin protein family member.

多肽

No

No

内部

酶联免疫吸附测定, 免疫印迹

一抗

未共轭

P22674

NP_066970

Western Blot of Cyclin O Antibody