产品简要
公司名称 :
Rockland Immunochemicals
产品类型 :
抗体
产品名称 :
酪氨酸羟化酶磷酸化S40抗体
目录 :
600-401-C99
规格 :
100微升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化
更多信息或购买 :
产品信息
目录号 :
600-401-C99
名称 :
抗酪氨酸羟化酶pS40(兔)抗体-600-401
显示名称 :
酪氨酸羟化酶磷酸化S40抗体
应用注释 :
Anti-Tyrosine Hydroxylase pS40 antibody is suitable for use in ELISA, Western Blotting, IHC and IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 42/44 kDa in size corresponding to the tyrosine hydroxylase proteins phosphorylated at Ser40 in the appropriate cell lysate or extract. Some higher molecular weight bands may be detected by the antibody depending upon the brain region being studied, protein loads and the detection methods used. The antibody has three orders of magnitude selectivity over dephospho TH.
缓冲液 :
0.01 M羟乙基哌嗪乙磺酸, 0.15 M氯化钠, pH值7.5
克隆性 :
多克隆
浓度值 :
Titrated value sufficient to run approximately 10 mini blots.
共轭 :
(None)
规格 :
100微升
默认单元 :
微升
ELISA稀释浓度 :
1:10,000
免疫组化稀释度 :
1:1000
免疫荧光显微镜稀释浓度 :
1:1000
免疫印迹稀释浓度 :
1:1000
有效期 :
Expiration date is one (1) year from date of opening.
格式 :
IgG
基因名称 :
Th
宿主动物 :
一般免责声明 :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
免疫原 :
Anti-Tyrosine Hydroxylase pS40 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 40 conjugated to KLH.
包装类型 :
干冰
物理状态 :
液体
纯度和特异性 :
Anti-Tyrosine Hydroxylase pS40 antibody is affinity purified from monospecific antiserum by immunoaffinity purification. Expect reactivity with the following species based on sequence homology: mouse. Cross reactivity from Tyrosine Hydroxylase pS40 from other sources has not been determined.
物种活性 :
mammalian, non-mammalian
稳定剂 :
0.1毫克/毫升牛血清白蛋白(BSA)-不含IgG和蛋白酶, 50%(v/v)甘油
储存 :
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
同义词 :
Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH
靶物种 :
大鼠
背景 :
Tyrosine Hydroxylase pS40 antibody recognizes Tyrosine hydroxylase (TH) which is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse. TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling. The activity of TH is also regulated by phosphorylation. Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs. Tyrosine Hydroxylase pS40 antibody is ideal for investigators involved in Neuronal Circuitry and disorders, and more generally in Neuroscience.
免疫原类型 :
多肽
低内毒素 :
No
翻译后的修饰作用 :
磷酸化
样品尺寸 :
No
靶活性结构域 :
内部
应用文本 :
酶联免疫吸附测定, 免疫组化, IF显微镜, 免疫印迹
类别 :
一抗
共轭名称 :
未共轭
UniProt数据库 :
P04177
NCBI :
NP_036872.1
最初图像名称 :
Western blot of Tyrosine Hydroxylase Ser40 Antibody
更多信息或购买 :
公司信息
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
orders@rockland-inc.com
https://www.rockland.com/
800-656-7625
公司总部: 美国
Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部,为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立,利用In vitro及In vivo方法制备并纯化单抗及多抗,这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究:Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。