抗体

JPH4抗体

600-401-CC9

100微克

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化

抗JPH4(兔)抗体-600-401

JPH4抗体

Anti-JPH4 Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 66 kDa in Western Blots of specific cell lysates and tissues.

0.01 M钠磷酸盐, 0.25 M氯化钠, pH值7.2

多克隆

1毫克/毫升

by UV absorbance at 280 nm

(None)

100微克

微克

1:10,000

2.5微克/毫升

20微克/毫升

1微克/毫升

Expiration date is one (1) year from date of opening.

IgG

JPH4

兔

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Anti-JPH4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the C-terminus of human JPH4.

干冰

Liquid (sterile filtered)

0.02%(w/v)叠氮化钠

Anti-JPH4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with JPH4 from other sources has not been determined.

人类, 小鼠, 大鼠

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

JPH4 Antibody, JP4, JPHL1, KIAA1831, Junctophilin-4, Junctophilin-like 1 protein, JP-4

人类

Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions.

多肽

No

No

C末端

酶联免疫吸附测定, 免疫组化, IF显微镜, 免疫印迹

一抗

未共轭

Q96JJ6

AAH55429

Western Blot of JPH4 Antibody