产品简要
公司名称 :
Rockland Immunochemicals
产品类型 :
抗体
产品名称 :
CDC42抗体
目录 :
600-401-P94
规格 :
100微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类,
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
产品信息
目录号 :
600-401-P94
名称 :
抗CDC42(兔)抗体-600-401
显示名称 :
CDC42抗体
应用注释 :
Anti-CDC42 is useful for Immunohistochemistry -P and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~21.3 kDa corresponding to the appropriate cell lysate or extract.
缓冲液 :
0.9毫克氯化钠, 0.2毫克Na2HPO4, 0.05毫克NaN3
克隆性 :
多克隆
浓度值 :
0.5毫克/毫升
浓度定义 :
by UV absorbance at 280 nm
共轭 :
(None)
规格 :
100微克
默认单元 :
微克
免疫组化稀释度 :
1:100-1:500
免疫印迹稀释浓度 :
0.5µg/毫升
有效期 :
Expiration date is one (1) year from date of opening.
格式 :
IgG
基因名称 :
CDC42
宿主动物 :
一般免责声明 :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
免疫原 :
CDC42 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human CDC42.
包装类型 :
Ambient
物理状态 :
冻干
防腐剂 :
0.05毫克硫柳汞
纯度和特异性 :
Anti-CDC42 antibody is directed against human CDC42 protein.  The product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on homology for the immunogen sequence.  Cross reactivity with CDC42 from other sources has not been determined.
重组缓冲液 :
Restore with deionized water (or equivalent)
重组体积 :
100微升
物种活性 :
人类, 小鼠, 大鼠, 牛
稳定剂 :
5毫克BSA
储存 :
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
同义词 :
G25K GTP结合蛋白
靶物种 :
人类
背景 :
Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene.CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. This antibody is suitable for researchers interested in cell signaling, epigenetics an cancer research.
免疫原类型 :
多肽
低内毒素 :
No
样品尺寸 :
No
靶活性结构域 :
内部
应用文本 :
免疫组化, 免疫印迹
类别 :
一抗
共轭名称 :
未共轭
UniProt数据库 :
P60953
NCBI :
NP_001034891.1
更多信息或购买 :
公司信息
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
orders@rockland-inc.com
https://www.rockland.com/
800-656-7625
公司总部: 美国
Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部,为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立,利用In vitro及In vivo方法制备并纯化单抗及多抗,这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究:Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。