产品简要
公司名称 :
Rockland Immunochemicals
产品类型 :
抗体
产品名称 :
I型胶原抗体生物素共轭标签
目录 :
600-406-103
规格 :
100
价格 :
https://www.rockland.com/search/?searchString=600-406-103
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
生物素
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 13
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 2c
Sinha S, Hoshino D, Hong N, Kirkbride K, Grega Larson N, Seiki M, et al. Cortactin promotes exosome secretion by controlling branched actin dynamics. J Cell Biol. 2016;214:197-213 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Gupta S, Itagaki R, Zheng X, Batkai S, Thum S, Ahmad F, et al. miR-21 promotes fibrosis in an acute cardiac allograft transplantation model. Cardiovasc Res. 2016;110:215-26 pubmed 出版商
D Alessandro Gabazza C, Yasuma T, Kobayashi T, Toda M, Abdel Hamid A, Fujimoto H, et al. Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis. Nat Commun. 2022;13:1558 pubmed 出版商
Reinhardt J, Breuer C. Fibrocytes: A Critical Review and Practical Guide. Front Immunol. 2021;12:784401 pubmed 出版商
Afroj T, Mitsuhashi A, Ogino H, Saijo A, Otsuka K, Yoneda H, et al. Blockade of PD-1/PD-L1 Pathway Enhances the Antigen-Presenting Capacity of Fibrocytes. J Immunol. 2021;206:1204-1214 pubmed 出版商
Oh H, Masuno K, Okusa N, Makita Y, Fujiwara S, Imamura Y. Effect of Orento, a Traditional Japanese Medicine, on IL-6, IL-8 Secretion, Type 1 Collagen Production and Alkaline Phosphatase Secretion in the Human Osteosarcoma Cell Line Saos-2. Medicines (Basel). 2020;7: pubmed 出版商
Palano G, Jansson M, Backmark A, Martinsson S, Sabirsh A, Hultenby K, et al. A high-content, in vitro cardiac fibrosis assay for high-throughput, phenotypic identification of compounds with anti-fibrotic activity. J Mol Cell Cardiol. 2020;142:105-117 pubmed 出版商
Kunimura K, Sakata D, Tun X, Uruno T, Ushijima M, Katakai T, et al. S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer's Patches. Cell Rep. 2019;29:2823-2834.e7 pubmed 出版商
Ozono Y, Shide K, Toyoshima F, Takaishi Y, Tsuchimochi M, Kamiunten A, et al. Monocyte-derived fibrocytes elimination had little contribution on liver fibrosis. Hepatobiliary Pancreat Dis Int. 2019;: pubmed 出版商
Heukels P, van Hulst J, van Nimwegen M, Boorsma C, Melgert B, van den Toorn L, et al. Fibrocytes are increased in lung and peripheral blood of patients with idiopathic pulmonary fibrosis. Respir Res. 2018;19:90 pubmed 出版商
Collins S, Chan Li Y, Oh M, Vigeland C, Limjunyawong N, Mitzner W, et al. Vaccinia vaccine-based immunotherapy arrests and reverses established pulmonary fibrosis. JCI Insight. 2016;1:e83116 pubmed
Buyandelger B, Mansfield C, Kostin S, Choi O, Roberts A, Ware J, et al. ZBTB17 (MIZ1) Is Important for the Cardiac Stress Response and a Novel Candidate Gene for Cardiomyopathy and Heart Failure. Circ Cardiovasc Genet. 2015;8:643-52 pubmed 出版商
Hashimoto N, Jin H, Liu T, Chensue S, Phan S. Bone marrow-derived progenitor cells in pulmonary fibrosis. J Clin Invest. 2004;113:243-52 pubmed
产品信息
目录号 :
600-406-103
名称 :
抗I型胶原(兔)抗体生物素共轭标签-600-406
显示名称 :
I型胶原抗体生物素共轭标签
应用注释 :
Anti-COLLAGEN Type I Antibody Biotin Conjugated has been tested by dot blot and Flow Cytometry and is suitable for western blot, immunoprecipitation, Flow Cytometry, and immunohistochemistry. Researchers should determine optimal titers for applications that are not stated below.
缓冲液 :
0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2
克隆性 :
多克隆
浓度值 :
1.0毫克/毫升
浓度定义 :
by UV absorbance at 280 nm
共轭 :
BAC
规格 :
100
默认单元 :
微克
ELISA稀释浓度 :
1:3, 000 - 1:6, 000
流式细胞仪稀释浓度 :
User Optimized
荧光蛋白值 :
10-20
免疫组化稀释度 :
1:50 - 1:200
免疫沉淀稀释度 :
1:100
免疫印迹稀释浓度 :
1:3, 000 - 1:6, 000
有效期 :
Expiration date is one (1) year from date of receipt.
格式 :
IgG
基因名称 :
COL1A1
宿主动物 :
一般免责声明 :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
免疫原 :
I型胶原来自人类和牛胎盘
包装类型 :
Ambient
物理状态 :
冻干
防腐剂 :
0.01%(w/v)叠氮化钠
纯度和特异性 :
This product has been prepared by immunoaffinity chromatography using immobilized antigens.  Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues.  This antibody reacts with most mammalian Type I collagens and has expected cross-reactivity with Type III and negligible cross reactivity with Type II, IV, V or VI collagens. Non-specific cross-reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins has not been tested.
重组缓冲液 :
Restore with deionized water (or equivalent)
重组体积 :
100微升
物种活性 :
人类;小鼠;大鼠
检测过的应用 :
Dot Blot; FC; Multiplex
Suggested Applications :
IF;免疫组化;免疫印迹
稳定剂 :
10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
储存 :
Store vial at 4° C prior to restoration.   Restore with 0.1 mL of deionized water (or equivalent). For extended storage aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.
同义词 :
rabbit anti-collagen type I antibody biotin conjugation, biotin conjugated rabbit anti-collagen type I antibody, Collagen Of Skin Tendon And Bone, Collagen Type 1 antibody, Collagen type I alpha 1 antibody, Collagen alpha-1 (I) chain, Alpha-1 type I collagen, type 1 procollagen alpha 1
靶物种 :
Mammalian
背景 :
COLLAGEN Type I Antibody Biotin Conjugated is specific for Collagen Type I. Collagen Type I (Type-I collagen) is the most abundant collagen of the human body. It is present in scar tissue, the end product when tissue heals by repair. It is also found in tendons, the endomysium of myofibrils and the organic part of bone. Anti-collagen Type I antibody is suitable for Cancer research and other general research.
免疫原类型 :
天然蛋白
低内毒素 :
No
样品尺寸 :
No
应用文本 :
酶联免疫吸附测定, 流式细胞仪, 免疫组化, 免疫沉淀, 免疫印迹
其他 :
User Optimized
类别 :
一抗
共轭名称 :
生物素
2024价格 :
$495.00
UniProt数据库 :
P02452
NCBI :
NP_000079.2
最初图像名称 :
FLOW Cytometry of Anti Collagen Type I Biotin Conjugated
更多信息或购买 :
公司信息
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
orders@rockland-inc.com
https://www.rockland.com/
800-656-7625
公司总部: 美国
Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部,为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立,利用In vitro及In vivo方法制备并纯化单抗及多抗,这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究:Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。