抗体

alpha突触核蛋白磷酸化S129抗体

612-401-C70

100微升

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定

抗alpha突触核蛋白pS129(兔)抗体-612-401

alpha突触核蛋白磷酸化S129抗体

Alpha Synuclein pS129 antibody is suitable for use in ELISA, Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 15 kDa in size corresponding to the alpha synuclein protein phosphorylated at Ser129 in the appropriate cell lysate or extract.

0.01 M羟乙基哌嗪乙磺酸, 0.15 M氯化钠, pH值7.5

多克隆

Titrated value sufficient to run approximately 10 mini blots.

(None)

100微升

微升

1:10,000

1:1000

Expiration date is one (1) year from date of opening.

IgG

Snca

兔

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Anti-Alpha Synuclein pS129 Antibody was produced by repeated immunizations with a synthetic phospho peptide corresponding to amino acid residues surrounding Ser129.

干冰

液体

Anti-Alpha Synuclein pS129 Antibody is directed against rat Alpha-synuclein phosphorylated at S129. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for phosphorylated Alpha-synuclein. Minimal reactivity occurs against non-phosphorylated Alpha-synuclein. Reactivity against Alpha-synuclein occurs from rat sources. Reactivity is expected against the following species based on 100% sequence homology: bovine, canine, and non-human primate.

人类, 小鼠, 大鼠

0.1毫克/毫升牛血清白蛋白(BSA)-不含IgG和蛋白酶, 50%(v/v)甘油

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Alpha-synuclein, Snca

大鼠

Alpha Synuclein pS129 Antibody detects Alpha-synuclein phosphorylated at S129. Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson’s disease (PD) and other neurodegenerative disorders. Mutation of the alpha-synuclein gene is associated with familial forms of PD. Recent evidence suggests that phosphorylation of alpha-synuclein at Ser129 plays a role in the formation of inclusions in PD. Anti-Alpha-synuclein pS129 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

多肽

No

磷酸化

No

内部

酶联免疫吸附测定, 免疫印迹

一抗

未共轭

P37377

NP_062042.1

Western blot of Alpha synuclein ser129 Antibody