c-v-erb-b2成红细胞白血病病毒致瘤基因2抗体 | Rockland Immunochemicals 900-C01-B37 产品信息

产品简要

公司名称 :

Rockland Immunochemicals

产品类型 :

抗体

产品名称 :

c-v-erb-b2成红细胞白血病病毒致瘤基因2抗体

900-C01-B37

规格 :

100微升

克隆性 :

单克隆

宿主 :

domestic rabbit

共轭标签 :

未共轭

克隆名称 :

SP3

反应物种 :

人类

应用 :

免疫印迹, 酶联免疫吸附测定, 免疫组化

更多信息或购买 :

Rockland Immunochemicals 产品网页

产品信息

目录号 :

900-C01-B37

名称 :

抗c-v-erb-b2成红细胞白血病病毒致瘤基因2(兔)单克隆抗体-900-C01

显示名称 :

c-v-erb-b2成红细胞白血病病毒致瘤基因2抗体

应用注释 :

erbB2 Antibody monoclonal antibody contains TBS/1% BSA and is suitable for ELISA, immunohistochemistry and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 185 kDa in size corresponding to c-erbB2 protein by western blotting in the appropriate cell lysate or extract. For immunohistochemistry, samples should be formalin fixed and paraffin embedded. Deparaffinize slides using xylene or xylene alternatives and graded alcohols. Staining requires boiling of sections in 10 mM citrate buffer pH 6.0 for 10 min followed by cooling at RT for 20 min. C-erbB2 is found in human breast carcinoma tissue at the cell membrane.

缓冲液 :

See application note.

克隆性 :

单克隆

克隆编号 :

SP3

共轭 :

(None)

规格 :

100微升

默认单元 :

微升

ELISA稀释浓度 :

1:10,000

免疫组化稀释度 :

1:100

免疫印迹稀释浓度 :

1:200-1:500

有效期 :

Expiration date is one (1) year from date of opening.

格式 :

CCS

基因名称 :

v-erb-b2成红细胞白血病病毒致瘤基因2

宿主动物 :

兔

一般免责声明 :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

免疫原 :

erbB2 monoclonal antibody was produced by repeated immunizations with a recombinant protein corresponding to amino acid residues encoding the extracellular domain of human c-erbB2 protein. The hybridoma was produced by fusing New Zealand White rabbit splenocytes and myeloma cells using conventional technology.

包装类型 :

Wet Ice

物理状态 :

Liquid (sterile filtered)

防腐剂 :

0.1%(w/v)叠氮化钠

纯度和特异性 :

Anti-erbB2 Antibody is clarified tissue culture supernate. The antibody is specific for human c-erbB2 protein. Cross-reactivity with c-erbB2 protein from other sources has not been determined.

物种活性 :

人类

稳定剂 :

10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

储存 :

Store at 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

子种类 :

IgG

同义词 :

rabbit anti-c-erbB2 Antibody, Receptor tyrosine-protein kinase erbB-2, p185erbB2, C-erbB-2, NEU proto-oncogene, tyrosine kinase-type cell surface receptor HER2, MLN 19, CD340

靶物种 :

人类

背景 :

The ERBB2 gene encodes a member of the tyrosine protein kinase superfamily that is an essential component of a neuregulin-receptor complex called c-erbB2 (also known as Receptor tyrosine-protein kinase erbB-2, p185erbB2, C-erbB-2, NEU proto-oncogene, tyrosine kinase-type cell surface receptor HER2, MLN 19 and CD340), although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. C-erbB2 is not activated by EGF, TGF-alpha and amphiregulin. Defects in ERBB2 are associated with gastric cancer, familial glioma of brain (glioblastoma multiforme), ovarian cancer and lung cancer (adenocarcinoma of lung). c-erbB2 antibody is ideal for Cancer and Signal Transduction research.

免疫原类型 :

重组蛋白

低内毒素 :

样品尺寸 :

靶活性结构域 :

细胞外

应用文本 :

酶联免疫吸附测定, 免疫组化, 免疫印迹

类别 :

一抗

共轭名称 :

未共轭

UniProt数据库 :

P04626

NCBI :

P04626.1

最初图像名称 :

抗c-v-erb-b2成红细胞白血病病毒致瘤基因2单克隆抗体-免疫组化

更多信息或购买 :

Rockland Immunochemicals 产品网页

公司信息

Rockland Immunochemicals

321 Jones Blvd
Pottstown, PA 19464

orders@rockland-inc.com

https://www.rockland.com/

800-656-7625

公司总部: 美国

Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部，为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立，利用In vitro及In vivo方法制备并纯化单抗及多抗，这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究：Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。