产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
YAP(63.7)抗体
目录 :
sc-101199
规格 :
100微克/毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
63.7
反应物种 :
人类, 小鼠, , 斑马鱼
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 其他, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 124
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:200; 图 6, s6
  • 免疫印迹; 人类; 图 5b
Mygland L, Brinch S, Strand M, Olsen P, Aizenshtadt A, Lund K, et al. Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. 2021;24:102807 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4f
Pocaterra A, Scattolin G, Romani P, Ament C, Ribback S, Chen X, et al. Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development. Commun Biol. 2021;4:763 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50
Jungwirth U, van Weverwijk A, Evans R, Jenkins L, Vicente D, Alexander J, et al. Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nat Commun. 2021;12:3516 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2b
Yuan T, Zheng R, Zhou X, Jin P, Huang Z, Zi X, et al. Abnormal Expression of YAP Is Associated With Proliferation, Differentiation, Neutrophil Infiltration, and Adverse Outcome in Patients With Nasal Inverted Papilloma. Front Cell Dev Biol. 2021;9:625251 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 4b
Della Chiara G, Gervasoni F, Fakiola M, Godano C, D Oria C, Azzolin L, et al. Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ. Nat Commun. 2021;12:2340 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 6c
Seo G, Han H, Vargas R, Yang B, Li X, Wang W. MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation. Cell Rep. 2020;32:107860 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 s6a
Waaler J, Mygland L, Tveita A, Strand M, Solberg N, Olsen P, et al. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Commun Biol. 2020;3:196 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1b
  • 免疫印迹; 人类; 图 1a
Bae S, Ni L, Luo X. STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism. elife. 2020;9: pubmed 出版商
  • 免疫沉淀; 人类; 图 2c
  • 免疫细胞化学; 人类; 图 1e
  • 免疫印迹; 人类; 1:500; 图 1f
An L, Nie P, Chen M, Tang Y, Zhang H, Guan J, et al. MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway. J Exp Med. 2020;217: pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 e5r
Diaz Cuadros M, Wagner D, Budjan C, Hubaud A, Tarazona O, Donelly S, et al. In vitro characterization of the human segmentation clock. Nature. 2020;580:113-118 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 2c
Quilichini E, Fabre M, Dirami T, Stedman A, De Vas M, Ozguc O, et al. Pancreatic ductal deletion of Hnf1b disrupts exocrine homeostasis, leads to pancreatitis and facilitates tumorigenesis. Cell Mol Gastroenterol Hepatol. 2019;: pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 1b
  • 免疫印迹; 人类; 1:500; 图 2e
Lee J, Chang J, Dominguez A, Lee H, Nam S, Chang J, et al. YAP-independent mechanotransduction drives breast cancer progression. Nat Commun. 2019;10:1848 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 3a
  • 免疫组化; 斑马鱼; 1:200; 图 s7b
Moro A, Driscoll T, Boraas L, Armero W, Kasper D, Baeyens N, et al. MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nat Cell Biol. 2019;21:348-358 pubmed 出版商
  • 免疫印迹; 人类; 图 1f
Rausch V, Bostrom J, Park J, Bravo I, Feng Y, Hay D, et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol. 2019;29:242-255.e6 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3d
Pan W, Moroishi T, Koo J, Guan K. Cell type-dependent function of LATS1/2 in cancer cell growth. Oncogene. 2019;38:2595-2610 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 1a
LeBlanc L, Lee B, Yu A, Kim M, Kambhampati A, Dupont S, et al. Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation. elife. 2018;7: pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s4i
Gut G, Herrmann M, Pelkmans L. Multiplexed protein maps link subcellular organization to cellular states. Science. 2018;361: pubmed 出版商
  • 免疫印迹; 人类; 图 1e
Liu H, Dai X, Cao X, Yan H, Ji X, Zhang H, et al. PRDM4 mediates YAP-induced cell invasion by activating leukocyte-specific integrin β2 expression. EMBO Rep. 2018;19: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1a
Ahmed A, Habeebu S, Sherman A, Ye S, Wood N, Chastain K, et al. Potential Value of YAP Staining in Rhabdomyosarcoma. J Histochem Cytochem. 2018;66:577-584 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 5b
Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 4b
Liu L, Wu B, Cai H, Li D, Ma Y, Zhu X, et al. Tiam1 promotes thyroid carcinoma metastasis by modulating EMT via Wnt/?-catenin signaling. Exp Cell Res. 2018;362:532-540 pubmed 出版商
  • 免疫印迹; 人类; 图 9e
Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s2c
Nardone G, Oliver De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nat Commun. 2017;8:15321 pubmed 出版商
  • 免疫沉淀; 人类; 图 3e
Zhu G, Chen Y, Zhang X, Wu Q, Zhao Y, Chen Y, et al. 12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT. Sci Rep. 2017;7:44940 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3b
Ragni C, Diguet N, Le Garrec J, Novotova M, Resende T, Pop S, et al. Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017;8:14582 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 S61B
Pósfai E, Petropoulos S, de Barros F, Schell J, Jurisica I, Sandberg R, et al. Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo. elife. 2017;6: pubmed 出版商
  • 免疫组化; 犬; 图 s3a
Valon L, Marín Llauradó A, Wyatt T, Charras G, Trepat X. Optogenetic control of cellular forces and mechanotransduction. Nat Commun. 2017;8:14396 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 2d
Heidary Arash E, Shiban A, Song S, Attisano L. MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells. EMBO Rep. 2017;18:420-436 pubmed 出版商
  • 免疫组化; 人类; 图 9d
Gouveia R, González Andrades E, Cardona J, González Gallardo C, Ionescu A, Garzon I, et al. Controlling the 3D architecture of Self-Lifting Auto-generated Tissue Equivalents (SLATEs) for optimized corneal graft composition and stability. Biomaterials. 2017;121:205-219 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1b
Moroishi T, Hayashi T, Pan W, Fujita Y, Holt M, Qin J, et al. The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity. Cell. 2016;167:1525-1539.e17 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
  • 免疫印迹; 小鼠; 1:1000
Martin K, Pritchett J, Llewellyn J, Mullan A, Athwal V, Dobie R, et al. PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis. Nat Commun. 2016;7:12502 pubmed 出版商
  • 免疫细胞化学; 人类; 1:75; 图 s6
  • 免疫组化; 人类; 1:250
  • 免疫印迹; 人类; 1:500; 图 6a
Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, et al. Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun. 2016;7:12237 pubmed 出版商
  • 免疫组化; 小鼠; 1:150; 图 5
  • 免疫印迹; 小鼠; 1:2000; 图 5
Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016;7:12309 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 2b
Mihajlovic A, Bruce A. Rho-associated protein kinase regulates subcellular localisation of Angiomotin and Hippo-signalling during preimplantation mouse embryo development. Reprod Biomed Online. 2016;33:381-90 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
  • 免疫印迹; 人类; 图 4
Ni T, Kuperwasser C. Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer. elife. 2016;5: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 1
Elosegui Artola A, Oria R, Chen Y, Kosmalska A, Pérez González C, Castro N, et al. Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity. Nat Cell Biol. 2016;18:540-8 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50; 图 3c
Cozzolino A, Noce V, Battistelli C, Marchetti A, Grassi G, Cicchini C, et al. Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes. Stem Cells Int. 2016;2016:5481493 pubmed 出版商
  • 免疫组化; 人类; 图 1h
  • 免疫印迹; 人类; 图 s1a
Thongon N, Castiglioni I, Zucal C, Latorre E, D Agostino V, Bauer I, et al. The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level. Oncotarget. 2016;7:26551-66 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 4
  • 免疫印迹; 人类; 1:1000; 图 3
Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, et al. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat Commun. 2016;7:10498 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4
  • 免疫印迹; 人类; 1:1000; 图 1
Meng Z, Moroishi T, Mottier Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 7
  • 免疫印迹; 人类; 1:500; 图 7
Choi H, Zhang H, Park H, Choi K, Lee H, Agrawal V, et al. Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2. Nat Commun. 2015;6:6943 pubmed 出版商
  • 其他; 人类; 1:200
  • 免疫印迹; 人类; 1:200
Wang M, Liu Y, Zou J, Yang R, Xuan F, Wang Y, et al. Transcriptional co-activator TAZ sustains proliferation and tumorigenicity of neuroblastoma by targeting CTGF and PDGF-β. Oncotarget. 2015;6:9517-30 pubmed
  • 免疫沉淀; 人类; 图 2
  • 免疫印迹; 人类; 图 2
Young K, Tweedie E, Conley B, Ames J, FitzSimons M, Brooks P, et al. BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses. PLoS ONE. 2015;10:e0122892 pubmed 出版商
  • 免疫印迹; 人类; 图 4d
Enzo E, Santinon G, Pocaterra A, Aragona M, Bresolin S, Forcato M, et al. Aerobic glycolysis tunes YAP/TAZ transcriptional activity. EMBO J. 2015;34:1349-70 pubmed 出版商
  • 免疫印迹; 人类
Ito T, Taniguchi H, Fukagai K, Okamuro S, Kobayashi A. Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis. PLoS ONE. 2015;10:e0118336 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Lin L, Sabnis A, Chan E, Olivas V, Cade L, Pazarentzos E, et al. The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies. Nat Genet. 2015;47:250-6 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Shen Z, Stanger B. YAP regulates S-phase entry in endothelial cells. PLoS ONE. 2015;10:e0117522 pubmed 出版商
  • 免疫印迹; 人类
Machado Neto J, Lazarini M, Favaro P, de Melo Campos P, Scopim Ribeiro R, Franchi Junior G, et al. ANKHD1 silencing inhibits Stathmin 1 activity, cell proliferation and migration of leukemia cells. Biochim Biophys Acta. 2015;1853:583-93 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6j
Li Q, Li S, Mana Capelli S, Roth Flach R, Danai L, Amcheslavsky A, et al. The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila. Dev Cell. 2014;31:291-304 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 8
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed 出版商
  • 免疫细胞化学; 人类
Yu W, Qiao Y, Tang X, Ma L, Wang Y, Zhang X, et al. Tumor suppressor long non-coding RNA, MT1DP is negatively regulated by YAP and Runx2 to inhibit FoxA1 in liver cancer cells. Cell Signal. 2014;26:2961-8 pubmed 出版商
  • 免疫沉淀; 人类; 图 5
  • 免疫印迹; 人类; 图 5
Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, et al. YAP/TAZ incorporation in the ?-catenin destruction complex orchestrates the Wnt response. Cell. 2014;158:157-70 pubmed 出版商
  • 免疫印迹; 人类
Machado Neto J, Lazarini M, Favaro P, Franchi G, Nowill A, Saad S, et al. ANKHD1, a novel component of the Hippo signaling pathway, promotes YAP1 activation and cell cycle progression in prostate cancer cells. Exp Cell Res. 2014;324:137-45 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 1
  • 免疫印迹; 小鼠; 图 s15
Reginensi A, Scott R, Gregorieff A, Bagherie Lachidan M, Chung C, Lim D, et al. Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. PLoS Genet. 2013;9:e1003380 pubmed 出版商
Uneda A, Kurozumi K, Fujimura A, Fujii K, Ishida J, Shimazu Y, et al. Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration. Acta Neuropathol Commun. 2021;9:29 pubmed 出版商
Park J, Jun K, Choi Y, Yoon E, Kim W, Jang Y, et al. CORO7 functions as a scaffold protein for the core kinase complex assembly of the Hippo pathway. J Biol Chem. 2021;296:100040 pubmed 出版商
Panciera T, Citron A, Di Biagio D, Battilana G, Gandin A, Giulitti S, et al. Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties. Nat Mater. 2020;19:797-806 pubmed 出版商
Irie K, Nagai T, Mizuno K. Furry protein suppresses nuclear localization of yes-associated protein (YAP) by activating NDR kinase and binding to YAP. J Biol Chem. 2020;295:3017-3028 pubmed 出版商
You E, Ko P, Jeong J, Keum S, Kim J, Seo Y, et al. Dynein-mediated nuclear translocation of yes-associated protein through microtubule acetylation controls fibroblast activation. Cell Mol Life Sci. 2020;: pubmed 出版商
Sayedyahossein S, Hedman A, Sacks D. Insulin suppresses transcriptional activity of yes-associated protein in insulin target cells. Mol Biol Cell. 2020;31:131-141 pubmed 出版商
Jain P, Guerreiro P, Canato S, Janody F. The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis. Sci Rep. 2019;9:19843 pubmed 出版商
Lee J, Dominguez A, Nam S, Stowers R, Qi L, Chaudhuri O. Identification of cell context-dependent YAP-associated proteins reveals β1 and β4 integrin mediate YAP translocation independently of cell spreading. Sci Rep. 2019;9:17188 pubmed 出版商
Fearing B, Jing L, Barcellona M, Witte S, Buchowski J, Zebala L, et al. Mechanosensitive transcriptional coactivators MRTF-A and YAP/TAZ regulate nucleus pulposus cell phenotype through cell shape. FASEB J. 2019;33:14022-14035 pubmed 出版商
Li R, Zhong C, Yu Y, Liu H, Sakurai M, Yu L, et al. Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures. Cell. 2019;179:687-702.e18 pubmed 出版商
Borreguero Muñoz N, Fletcher G, Aguilar Aragon M, Elbediwy A, Vincent Mistiaen Z, Thompson B. The Hippo pathway integrates PI3K-Akt signals with mechanical and polarity cues to control tissue growth. PLoS Biol. 2019;17:e3000509 pubmed 出版商
Stanton A, Tong X, Yang F. Varying solvent type modulates collagen coating and stem cell mechanotransduction on hydrogel substrates. APL Bioeng. 2019;3:036108 pubmed 出版商
Sliogeryte K, Gavara N. Vimentin Plays a Crucial Role in Fibroblast Ageing by Regulating Biophysical Properties and Cell Migration. Cells. 2019;8: pubmed 出版商
Peyret G, Mueller R, D Alessandro J, Begnaud S, Marcq P, Mège R, et al. Sustained Oscillations of Epithelial Cell Sheets. Biophys J. 2019;117:464-478 pubmed 出版商
Panková D, Jiang Y, Chatzifrangkeskou M, Vendrell I, Buzzelli J, Ryan A, et al. RASSF1A controls tissue stiffness and cancer stem-like cells in lung adenocarcinoma. EMBO J. 2019;38:e100532 pubmed 出版商
Kumar D, Nitzan E, Kalcheim C. YAP promotes neural crest emigration through interactions with BMP and Wnt activities. Cell Commun Signal. 2019;17:69 pubmed 出版商
Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, et al. The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes. Cell Rep. 2019;27:3533-3546.e7 pubmed 出版商
Hao F, Xu Q, Wang J, Yu S, Chang H, Sinnett Smith J, et al. Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice. PLoS ONE. 2019;14:e0216603 pubmed 出版商
Foyt D, Taheem D, Ferreira S, Norman M, Petzold J, Jell G, et al. Hypoxia impacts human MSC response to substrate stiffness during chondrogenic differentiation. Acta Biomater. 2019;89:73-83 pubmed 出版商
Hino N, Ichikawa T, Kimura Y, Matsuda M, Ueda K, Kioka N. An amphipathic helix of vinexin α is necessary for a substrate stiffness-dependent conformational change in vinculin. J Cell Sci. 2019;132: pubmed 出版商
Łastowska M, Trubicka J, Karkucinska Wieckowska A, Kaleta M, Tarasińska M, Perek Polnik M, et al. Immunohistochemical detection of ALK protein identifies APC mutated medulloblastoma and differentiates the WNT-activated medulloblastoma from other types of posterior fossa childhood tumors. Brain Tumor Pathol. 2019;36:1-6 pubmed 出版商
Frum T, Murphy T, Ralston A. HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo. elife. 2018;7: pubmed 出版商
Moreno Vicente R, Pavón D, Martin Padura I, Català Montoro M, Díez Sánchez A, Quílez Álvarez A, et al. Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP. Cell Rep. 2018;25:1622-1635.e6 pubmed 出版商
Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, et al. The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ. Nature. 2018;563:265-269 pubmed 出版商
Liu Y, McGuire A, Lou H, Li T, Tok J, Cui B, et al. Soft conductive micropillar electrode arrays for biologically relevant electrophysiological recording. Proc Natl Acad Sci U S A. 2018;115:11718-11723 pubmed 出版商
Zhao A, Dai Y, Lian J, Huang Y, Lin J, Dai Y, et al. YAP regulates ALDH1A1 expression and stem cell property of bladder cancer cells. Onco Targets Ther. 2018;11:6657-6663 pubmed 出版商
Han H, Qi R, Zhou J, Ta A, Yang B, Nakaoka H, et al. Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction. Mol Cell. 2018;72:328-340.e8 pubmed 出版商
Vincent Mistiaen Z, Elbediwy A, Vanyai H, Cotton J, Stamp G, Nye E, et al. YAP drives cutaneous squamous cell carcinoma formation and progression. elife. 2018;7: pubmed 出版商
Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, et al. Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4. Nat Med. 2018;24:1599-1610 pubmed 出版商
Bonse J, Wennmann D, Kremerskothen J, Weide T, Michgehl U, Pavenstadt H, et al. Nuclear YAP localization as a key regulator of podocyte function. Cell Death Dis. 2018;9:850 pubmed 出版商
Kuroda M, Ueda K, Kioka N. Vinexin family (SORBS) proteins regulate mechanotransduction in mesenchymal stem cells. Sci Rep. 2018;8:11581 pubmed 出版商
Astone M, Lai J, Dupont S, Stainier D, Argenton F, Vettori A. Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development. Sci Rep. 2018;8:10189 pubmed 出版商
Kato K, Diéguez Hurtado R, Park D, Hong S, Kato Azuma S, Adams S, et al. Pulmonary pericytes regulate lung morphogenesis. Nat Commun. 2018;9:2448 pubmed 出版商
Ege N, Dowbaj A, Jiang M, Howell M, Hooper S, Foster C, et al. Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export. Cell Syst. 2018;6:692-708.e13 pubmed 出版商
Miskolczi Z, Smith M, Rowling E, Ferguson J, Barriuso J, Wellbrock C. Collagen abundance controls melanoma phenotypes through lineage-specific microenvironment sensing. Oncogene. 2018;37:3166-3182 pubmed 出版商
Guo L, Cai T, Chen K, Wang R, Wang J, Cui C, et al. Kindlin-2 regulates mesenchymal stem cell differentiation through control of YAP1/TAZ. J Cell Biol. 2018;217:1431-1451 pubmed 出版商
Zhou B, Flodby P, Luo J, Castillo D, Liu Y, Yu F, et al. Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis. J Clin Invest. 2018;128:970-984 pubmed 出版商
He L, Tao J, Maity D, Si F, Wu Y, Wu T, et al. Role of membrane-tension gated Ca2+ flux in cell mechanosensation. J Cell Sci. 2018;131: pubmed 出版商
Elosegui Artola A, Andreu I, Beedle A, Lezamiz A, Uroz M, Kosmalska A, et al. Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores. Cell. 2017;171:1397-1410.e14 pubmed 出版商
Hubaud A, Regev I, Mahadevan L, Pourquie O. Excitable Dynamics and Yap-Dependent Mechanical Cues Drive the Segmentation Clock. Cell. 2017;171:668-682.e11 pubmed 出版商
Abagnale G, Sechi A, Steger M, Zhou Q, Kuo C, Aydin G, et al. Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies. Stem Cell Reports. 2017;9:654-666 pubmed 出版商
Sarkar S, Bristow C, Dey P, Rai K, Perets R, Ramirez Cardenas A, et al. PRKCI promotes immune suppression in ovarian cancer. Genes Dev. 2017;31:1109-1121 pubmed 出版商
Dieffenbach P, Haeger C, Coronata A, Choi K, Varelas X, Tschumperlin D, et al. Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2. Am J Physiol Lung Cell Mol Physiol. 2017;313:L628-L647 pubmed 出版商
Trubicka J, Å»emojtel T, Hecht J, Falana K, Piekutowska Abramczuk D, PÅ‚oski R, et al. The germline variants in DNA repair genes in pediatric medulloblastoma: a challenge for current therapeutic strategies. BMC Cancer. 2017;17:239 pubmed 出版商
Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson Peer K, et al. YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis. elife. 2017;6: pubmed 出版商
Chlapek P, Zitterbart K, Kren L, Filipová L, Sterba J, Veselska R. Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups. PLoS ONE. 2017;12:e0172552 pubmed 出版商
Sorrentino G, Ruggeri N, Zannini A, Ingallina E, Bertolio R, Marotta C, et al. Glucocorticoid receptor signalling activates YAP in breast cancer. Nat Commun. 2017;8:14073 pubmed 出版商
Sero J, Bakal C. Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion. Cell Syst. 2017;4:84-96.e6 pubmed 出版商
Moon S, Kim W, Kim S, Kim Y, Song Y, Bilousov O, et al. Phosphorylation by NLK inhibits YAP-14-3-3-interactions and induces its nuclear localization. EMBO Rep. 2017;18:61-71 pubmed 出版商
Elbediwy A, Vincent Mistiaen Z, Spencer Dene B, Stone R, Boeing S, Wculek S, et al. Integrin signalling regulates YAP and TAZ to control skin homeostasis. Development. 2016;143:1674-87 pubmed 出版商
Grampa V, Delous M, Zaidan M, Odye G, Thomas S, Elkhartoufi N, et al. Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation. PLoS Genet. 2016;12:e1005894 pubmed 出版商
Hansen C, Ng Y, Lam W, Plouffe S, Guan K. The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1. Cell Res. 2015;25:1299-313 pubmed 出版商
Heo S, Thorpe S, Driscoll T, Duncan R, Lee D, Mauck R. Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells. Sci Rep. 2015;5:16895 pubmed 出版商
Taccioli C, Sorrentino G, Zannini A, Caroli J, Beneventano D, Anderlucci L, et al. MDP, a database linking drug response data to genomic information, identifies dasatinib and statins as a combinatorial strategy to inhibit YAP/TAZ in cancer cells. Oncotarget. 2015;6:38854-65 pubmed 出版商
Archibald A, Al Masri M, Liew Spilger A, McCaffrey L. Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling. Mol Biol Cell. 2015;26:3578-95 pubmed 出版商
Bagherie Lachidan M, Reginensi A, Pan Q, Zaveri H, Scott D, Blencowe B, et al. Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool. Development. 2015;142:2564-73 pubmed 出版商
Liu F, Lagares D, Choi K, Stopfer L, Marinković A, Vrbanac V, et al. Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis. Am J Physiol Lung Cell Mol Physiol. 2015;308:L344-57 pubmed 出版商
Wennmann D, Vollenbröker B, Eckart A, Bonse J, Erdmann F, Wolters D, et al. The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes. Cell Death Dis. 2014;5:e1519 pubmed 出版商
Whittier K, Boese E, Gibson Corley K, Kirby P, Darbro B, Qian Q, et al. G-protein coupled receptor expression patterns delineate medulloblastoma subgroups. Acta Neuropathol Commun. 2013;1:66 pubmed 出版商
Xiao W, Wang J, Ou C, Zhang Y, Ma L, Weng W, et al. Mutual interaction between YAP and c-Myc is critical for carcinogenesis in liver cancer. Biochem Biophys Res Commun. 2013;439:167-72 pubmed 出版商
Min H, Lee J, Kim S, Park S. Genetic grouping of medulloblastomas by representative markers in pathologic diagnosis. Transl Oncol. 2013;6:265-72 pubmed
Michaloglou C, Lehmann W, Martin T, Delaunay C, Hueber A, Barys L, et al. The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity. PLoS ONE. 2013;8:e61916 pubmed 出版商
Wang J, Ma L, Weng W, Qiao Y, Zhang Y, He J, et al. Mutual interaction between YAP and CREB promotes tumorigenesis in liver cancer. Hepatology. 2013;58:1011-20 pubmed 出版商
Venerando A, Girardi C, Ruzzene M, Pinna L. Pyrvinium pamoate does not activate protein kinase CK1, but promotes Akt/PKB down-regulation and GSK3 activation. Biochem J. 2013;452:131-7 pubmed 出版商
Ren Y, Chaerkady R, Hu S, Wan J, Qian J, Zhu H, et al. Unbiased discovery of interactions at a control locus driving expression of the cancer-specific therapeutic and diagnostic target, mesothelin. J Proteome Res. 2012;11:5301-10 pubmed 出版商
Taylor M, Northcott P, Korshunov A, Remke M, Cho Y, Clifford S, et al. Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol. 2012;123:465-72 pubmed 出版商
Nord H, Pfeifer S, Nilsson P, Sandgren J, Popova S, Stromberg B, et al. Novel amplifications in pediatric medulloblastoma identified by genome-wide copy number profiling. J Neurooncol. 2012;107:37-49 pubmed 出版商
Silvis M, Kreger B, Lien W, Klezovitch O, Rudakova G, Camargo F, et al. ?-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1. Sci Signal. 2011;4:ra33 pubmed 出版商
Ren Y, Patel K, Paun B, Kern S. Structural analysis of the cancer-specific promoter in mesothelin and in other genes overexpressed in cancers. J Biol Chem. 2011;286:11960-9 pubmed 出版商
Ellison D, Dalton J, Kocak M, Nicholson S, Fraga C, Neale G, et al. Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups. Acta Neuropathol. 2011;121:381-96 pubmed 出版商
产品信息
产品名称 :
YAP(63.7)抗体
基因名称 :
YAP1
规格 :
100微克/毫升
目录号 :
sc-101199
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
YAP
反应物种 :
m, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), 酶联免疫吸附测定
表位 :
FL(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。