产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
Rb (IF8) Antibody
目录 :
sc-102
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
IF8
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 其他, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 62
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 s1d
Ruscetti M, Leibold J, Bott M, Fennell M, Kulick A, Salgado N, et al. NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science. 2018;362:1416-1422 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
He D, Ren B, Liu S, Tan L, Cieply K, Tseng G, et al. Oncogenic activity of amplified miniature chromosome maintenance 8 in human malignancies. Oncogene. 2017;36:3629-3639 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 3d
  • 免疫印迹; 人类; 图 5f
Choiniere J, Wu J, Wang L. Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins. Mol Pharmacol. 2017;91:189-196 pubmed 出版商
  • 免疫印迹; 人类; 图 6b
Cunningham C, Li S, Vizeacoumar F, Bhanumathy K, Lee J, Parameswaran S, et al. Therapeutic relevance of the protein phosphatase 2A in cancer. Oncotarget. 2016;7:61544-61561 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 2
Ercilla A, Llopis A, Feu S, Aranda S, Ernfors P, Freire R, et al. New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress. Nucleic Acids Res. 2016;44:4745-62 pubmed 出版商
  • 其他; 人类; 图 st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Vijayalingam S, Subramanian T, Zhao L, Chinnadurai G. The Cellular Protein Complex Associated with a Transforming Region of E1A Contains c-MYC. J Virol. 2016;90:1070-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 st1
Hwang J, Sung W, Tu H, Hsieh K, Yeh C, Chen C, et al. The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma. PLoS ONE. 2015;10:e0139435 pubmed 出版商
  • 免疫组化; 小鼠
Costales M, Lopez F, García Inclán C, Fernandez S, Marcos C, Llorente J, et al. Establishment and characterization of an orthotopic sinonasal squamous cell carcinoma mouse model. Head Neck. 2015;37:1769-75 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Tanaka T, Iino M. Knockdown of Sec8 promotes cell-cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins. FEBS J. 2014;281:1068-84 pubmed 出版商
  • 免疫印迹; 人类
Garcia Jove Navarro M, Basset C, Arcondeguy T, Touriol C, Perez G, Prats H, et al. Api5 contributes to E2F1 control of the G1/S cell cycle phase transition. PLoS ONE. 2013;8:e71443 pubmed 出版商
  • 免疫印迹; 人类
Jarboui M, Bidoia C, Woods E, Roe B, Wynne K, Elia G, et al. Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus. PLoS ONE. 2012;7:e48702 pubmed 出版商
  • 免疫印迹; 人类
Pappa A, Brown D, Koutalos Y, DeGregori J, White C, Vasiliou V. Human aldehyde dehydrogenase 3A1 inhibits proliferation and promotes survival of human corneal epithelial cells. J Biol Chem. 2005;280:27998-8006 pubmed
McLaughlin R, He J, van der Noord V, Redel J, Foekens J, Martens J, et al. A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy. Breast Cancer Res. 2019;21:77 pubmed 出版商
Chen M, Wan L, Zhang J, Zhang J, Méndez L, Clohessy J, et al. Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism. Nat Commun. 2018;9:159 pubmed 出版商
Wang Y, Liui H, Fu R, Wang Z, Ren H, Dai Z, et al. HDAC Inhibitor Oxamflatin Induces Morphological Changes and has Strong Cytostatic Effects in Ovarian Cancer Cell Lines. Curr Mol Med. 2016;16:232-42 pubmed
Wu J, Simonette R, Nguyen H, Doan H, Rady P, Tyring S. Emerging differential roles of the pRb tumor suppressor in trichodysplasia spinulosa-associated polyomavirus and Merkel cell polyomavirus pathogeneses. J Clin Virol. 2016;76:40-3 pubmed 出版商
Caligiuri I, Toffoli G, Giordano A, Rizzolio F. pRb controls estrogen receptor alpha protein stability and activity. Oncotarget. 2013;4:875-83 pubmed
Chen Y, Chu H, Ze Shiang Lin -, Shiah W, Chou C, Klimstra D, et al. p16 Stimulates CDC42-dependent migration of hepatocellular carcinoma cells. PLoS ONE. 2013;8:e69389 pubmed 出版商
Szalmás A, Gyöngyösi E, Ferenczi A, László B, Karosi T, Csomor P, et al. Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein. Virol J. 2013;10:79 pubmed 出版商
Cho H, Hayami S, Toyokawa G, Maejima K, Yamane Y, Suzuki T, et al. RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation. Neoplasia. 2012;14:476-86 pubmed
Nande R, Di Benedetto A, Aimola P, de Carlo F, Carper M, Claudio C, et al. Targeting a newly established spontaneous feline fibrosarcoma cell line by gene transfer. PLoS ONE. 2012;7:e37743 pubmed 出版商
Ginestier C, Monville F, Wicinski J, Cabaud O, Cervera N, Josselin E, et al. Mevalonate metabolism regulates Basal breast cancer stem cells and is a potential therapeutic target. Stem Cells. 2012;30:1327-37 pubmed 出版商
Rizzolio F, Caligiuri I, Lucchetti C, Fratamico R, Tomei V, Gallo G, et al. Dissecting Pin1 and phospho-pRb regulation. J Cell Physiol. 2013;228:73-7 pubmed 出版商
Taura M, Suico M, Koyama K, Komatsu K, Miyakita R, Matsumoto C, et al. Rb/E2F1 regulates the innate immune receptor Toll-like receptor 3 in epithelial cells. Mol Cell Biol. 2012;32:1581-90 pubmed 出版商
Kothari V, Mulherkar R. Inhibition of cyclin D1 by shRNA is associated with enhanced sensitivity to conventional therapies for head and neck squamous cell carcinoma. Anticancer Res. 2012;32:121-8 pubmed
Vranic S, Gatalica Z, Wang Z. Update on the molecular profile of the MDA-MB-453 cell line as a model for apocrine breast carcinoma studies. Oncol Lett. 2011;2:1131-1137 pubmed
Zheng Z, Li L, Liu X, Wang D, Tu B, Wang L, et al. 5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins. FASEB J. 2012;26:449-59 pubmed 出版商
Camboni M, Hammond S, Martin L, Martin P. Induction of a regenerative microenvironment in skeletal muscle is sufficient to induce embryonal rhabdomyosarcoma in p53-deficient mice. J Pathol. 2012;226:40-9 pubmed 出版商
Musumeci G, Cardile V, Fenga C, Caggia S, Loreto C. Mineral fibre toxicity: expression of retinoblastoma (Rb) and phospho-retinoblastoma (pRb) protein in alveolar epithelial and mesothelial cell lines exposed to fluoro-edenite fibres. Cell Biol Toxicol. 2011;27:217-25 pubmed 出版商
Heijink D, Fehrmann R, de Vries E, Koornstra J, Oosterhuis D, van der Zee A, et al. A bioinformatical and functional approach to identify novel strategies for chemoprevention of colorectal cancer. Oncogene. 2011;30:2026-36 pubmed 出版商
Cimica V, Smith M, Zhang Z, Mathur D, Mani S, Kalpana G. Potent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen. BMC Cancer. 2010;10:634 pubmed 出版商
Nakaya R, Takaya J, Onuki T, Moritani M, Nozaki N, Ishimi Y. Identification of proteins that may directly interact with human RPA. J Biochem. 2010;148:539-47 pubmed 出版商
Sherrill J, Sparks M, Dennis J, Mansour M, Kemppainen B, Bartol F, et al. Developmental exposures of male rats to soy isoflavones impact Leydig cell differentiation. Biol Reprod. 2010;83:488-501 pubmed 出版商
Fernandez K, Serinagaoglu Y, Hammond S, Martin L, Martin P. Mice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts. Am J Pathol. 2010;176:416-34 pubmed 出版商
Naryzhny S. Blue Dry Western: simple, economic, informative, and fast way of immunodetection. Anal Biochem. 2009;392:90-5 pubmed 出版商
Batsi C, Markopoulou S, Kontargiris E, Charalambous C, Thomas C, Christoforidis S, et al. Bcl-2 blocks 2-methoxyestradiol induced leukemia cell apoptosis by a p27(Kip1)-dependent G1/S cell cycle arrest in conjunction with NF-kappaB activation. Biochem Pharmacol. 2009;78:33-44 pubmed 出版商
Padmakumar V, Aleem E, Berthet C, Hilton M, Kaldis P. Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53. Mol Cell Biol. 2009;29:2582-93 pubmed 出版商
Stengel K, Thangavel C, Solomon D, Angus S, Zheng Y, Knudsen E. Retinoblastoma/p107/p130 pocket proteins: protein dynamics and interactions with target gene promoters. J Biol Chem. 2009;284:19265-71 pubmed 出版商
Cheung A, Lung H, Hung S, Law E, Cheng Y, Yau W, et al. Functional analysis of a cell cycle-associated, tumor-suppressive gene, protein tyrosine phosphatase receptor type G, in nasopharyngeal carcinoma. Cancer Res. 2008;68:8137-45 pubmed 出版商
Rieber M, Rieber M. Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagy. Cancer Biol Ther. 2008;7:1561-6 pubmed
Hu H, Zielinska Kwiatkowska A, Munro K, Wilcox J, Wu D, Yang L, et al. EWS/FLI1 suppresses retinoblastoma protein function and senescence in Ewing's sarcoma cells. J Orthop Res. 2008;26:886-93 pubmed 出版商
Jackman K, Frye C, Hunger S. Flavopiridol displays preclinical activity in acute lymphoblastic leukemia. Pediatr Blood Cancer. 2008;50:772-8 pubmed
Kohyama S, Morimoto Y, Nakai K, Kaji T, Tokumaru A, Nawashiro H, et al. Effectiveness of narrow-band ultraviolet-B phototherapy for prevention of intimal hyperplasia in a rat carotid balloon injury model. Lasers Surg Med. 2007;39:659-66 pubmed
Holaska J, Wilson K. An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture. Biochemistry. 2007;46:8897-908 pubmed
Marusyk A, Wheeler L, Mathews C, DeGregori J. p53 mediates senescence-like arrest induced by chronic replicational stress. Mol Cell Biol. 2007;27:5336-51 pubmed
Yosifov D, Dineva I, Zaharieva M, Konstantinov S, Berger M. The expression level of the tumor suppressor retinoblastoma protein (Rb) influences the antileukemic efficacy of erucylphospho-N,N,N-trimethylpropylammonium (ErPC3). Cancer Biol Ther. 2007;6:930-5 pubmed
Morelli F, Peluso G, Petillo O, Giannattasio A, Filosa S, Motta C, et al. The immunomodulatory protein SV-IV protects serum-deprived cells against apoptosis but not against G0/G1 arrest: possible implications for the survival of implanting embryo. J Cell Physiol. 2007;212:610-25 pubmed
Chen Z, Fu L, Herrero R, Schiffman M, Burk R. Identification of a novel human papillomavirus (HPV97) related to HPV18 and HPV45. Int J Cancer. 2007;121:193-8 pubmed
Takahashi A, Ohtani N, Yamakoshi K, Iida S, Tahara H, Nakayama K, et al. Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence. Nat Cell Biol. 2006;8:1291-7 pubmed
Pasder O, Shpungin S, Salem Y, Makovsky A, Vilchick S, Michaeli S, et al. Downregulation of Fer induces PP1 activation and cell-cycle arrest in malignant cells. Oncogene. 2006;25:4194-206 pubmed
Mao X, Orchard G, Vonderheid E, Nowell P, Bagot M, Bensussan A, et al. Heterogeneous abnormalities of CCND1 and RB1 in primary cutaneous T-Cell lymphomas suggesting impaired cell cycle control in disease pathogenesis. J Invest Dermatol. 2006;126:1388-95 pubmed
Liu C, Wang R, Berndt N. Protein phosphatase 1alpha activity prevents oncogenic transformation. Mol Carcinog. 2006;45:648-56 pubmed
Bahri R, Hirsch F, Josse A, Rouas Freiss N, Bidere N, Vasquez A, et al. Soluble HLA-G inhibits cell cycle progression in human alloreactive T lymphocytes. J Immunol. 2006;176:1331-9 pubmed
Collins A, Nakahara T, Do A, Lambert P. Interactions with pocket proteins contribute to the role of human papillomavirus type 16 E7 in the papillomavirus life cycle. J Virol. 2005;79:14769-80 pubmed
Kato H, Inoue T, Asanoma K, Nishimura C, Matsuda T, Wake N. Induction of human endometrial cancer cell senescence through modulation of HIF-1alpha activity by EGLN1. Int J Cancer. 2006;118:1144-53 pubmed
Yao C, Lai G, Chan C, Cheng A, Yang Y, Chuang S. Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone. Int J Cancer. 2006;118:773-9 pubmed
Varela I, Cadinanos J, Pendas A, Gutierrez Fernandez A, Folgueras A, Sanchez L, et al. Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation. Nature. 2005;437:564-8 pubmed
Esposito V, Baldi A, De Luca A, Tonini G, Vincenzi B, Santini D, et al. Cell cycle related proteins as prognostic parameters in radically resected non-small cell lung cancer. J Clin Pathol. 2005;58:734-9 pubmed
Gery S, Tanosaki S, Hofmann W, Koppel A, Koeffler H. C/EBPdelta expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation. Oncogene. 2005;24:1589-97 pubmed
Loercher A, Tank E, Delston R, Harbour J. MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A. J Cell Biol. 2005;168:35-40 pubmed
Halaban R, Cheng E, Smicun Y, Germino J. Deregulated E2F transcriptional activity in autonomously growing melanoma cells. J Exp Med. 2000;191:1005-16 pubmed
产品信息
产品名称 :
Rb (IF8) Antibody
基因名称 :
视网膜成神经细胞瘤相关蛋白
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-102
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
Rb
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。