产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
表皮生长因子受体(528)抗体
目录 :
sc-120
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
528
反应物种 :
中国人仓鼠, 仓鼠, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 67
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 中国人仓鼠; 图 1
Hang Q, Isaji T, Hou S, Zhou Y, Fukuda T, Gu J. N-Glycosylation of integrin ?5 acts as a switch for EGFR-mediated complex formation of integrin ?5?1 to ?6?4. Sci Rep. 2016;6:33507 pubmed 出版商
  • 流式细胞仪; 仓鼠; 图 1d
Kimani S, Kumar S, Davra V, Chang Y, Kasikara C, Geng K, et al. Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase. Cell Commun Signal. 2016;14:19 pubmed 出版商
  • 免疫细胞化学; scFv; 图 3
Chamberland J, Antonow L, Dias Santos M, Ritter B. NECAP2 controls clathrin coat recruitment to early endosomes for fast endocytic recycling. J Cell Sci. 2016;129:2625-37 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 7b
He F, Wei L, Luo W, Liao Z, Li B, Zhou X, et al. Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS. Oncotarget. 2016;7:37000-37012 pubmed 出版商
  • 流式细胞仪; 人类; 1:100; 图 3d
Vennin C, Spruyt N, Dahmani F, Julien S, Bertucci F, Finetti P, et al. H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b. Oncotarget. 2015;6:29209-23 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Wu Y, Deng W, Klinke D. Exosomes: improved methods to characterize their morphology, RNA content, and surface protein biomarkers. Analyst. 2015;140:6631-42 pubmed 出版商
  • 抑制或激活实验; 人类; 1:200
Teng Y, Radde B, Litchfield L, Ivanova M, Prough R, Clark B, et al. Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. J Biol Chem. 2015;290:15799-811 pubmed 出版商
  • 免疫沉淀; 人类
Young O, Tang Z, Niven Fairchild T, Tadesse S, Krikun G, Norwitz E, et al. Toll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophages. Am J Reprod Immunol. 2015;73:22-35 pubmed 出版商
  • 免疫印迹; 人类
Hamdollah Zadeh M, Amin E, Hoareau Aveilla C, Domingo E, Symonds K, Ye X, et al. Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance. Mol Oncol. 2015;9:167-78 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Zhang X, Zhang H, Tighiouart M, Lee J, Shin H, Khuri F, et al. Synergistic inhibition of head and neck tumor growth by green tea (-)-epigallocatechin-3-gallate and EGFR tyrosine kinase inhibitor. Int J Cancer. 2008;123:1005-14 pubmed 出版商
Chen M, Choi S, Jung O, Wen T, Baum C, Thapa N, et al. The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif. Sci Rep. 2019;9:9126 pubmed 出版商
Rivero Ríos P, Romo Lozano M, Madero Pérez J, Thomas A, Biosa A, Greggio E, et al. The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A. J Biol Chem. 2019;294:4738-4758 pubmed 出版商
de Beer M, Kuipers J, van Bergen en Henegouwen P, Giepmans B. A small protein probe for correlated microscopy of endogenous proteins. Histochem Cell Biol. 2018;149:261-268 pubmed 出版商
Vaishnavi A, Schubert L, Rix U, Marek L, Le A, Keysar S, et al. EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Cancer Res. 2017;77:3551-3563 pubmed 出版商
Ortiz Zapater E, Lee R, Owen W, Weitsman G, Fruhwirth G, Dunn R, et al. MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition. PLoS ONE. 2017;12:e0170798 pubmed 出版商
Dinish U, Balasundaram G, Chang Y, Olivo M. Actively targeted in vivo multiplex detection of intrinsic cancer biomarkers using biocompatible SERS nanotags. Sci Rep. 2014;4:4075 pubmed 出版商
Stoczyńska Fidelus E, Piaskowski S, Bienkowski M, Banaszczyk M, Hulas Bigoszewska K, Winiecka Klimek M, et al. The failure in the stabilization of glioblastoma-derived cell lines: spontaneous in vitro senescence as the main culprit. PLoS ONE. 2014;9:e87136 pubmed 出版商
Konkel M, Samuelson D, Eucker T, Shelden E, O Loughlin J. Invasion of epithelial cells by Campylobacter jejuni is independent of caveolae. Cell Commun Signal. 2013;11:100 pubmed 出版商
Leroy M, Perroud J, Darbellay B, Bernheim L, Konig S. Epidermal growth factor receptor down-regulation triggers human myoblast differentiation. PLoS ONE. 2013;8:e71770 pubmed 出版商
Wolf Goldberg T, Barbul A, Ben Dov N, Korenstein R. Low electric fields induce ligand-independent activation of EGF receptor and ERK via electrochemical elevation of H(+) and ROS concentrations. Biochim Biophys Acta. 2013;1833:1396-408 pubmed 出版商
Moretti J, Chastagner P, Liang C, Cohn M, Israel A, Brou C. The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation. J Biol Chem. 2012;287:29429-41 pubmed 出版商
Pan S, Chen R, Brand R, Hawley S, Tamura Y, Gafken P, et al. Multiplex targeted proteomic assay for biomarker detection in plasma: a pancreatic cancer biomarker case study. J Proteome Res. 2012;11:1937-48 pubmed 出版商
U S D, Fu C, Soh K, Ramaswamy B, Kumar A, Olivo M. Highly sensitive SERS detection of cancer proteins in low sample volume using hollow core photonic crystal fiber. Biosens Bioelectron. 2012;33:293-8 pubmed 出版商
Wilson K, Mill C, Gallo R, Cameron E, VanBrocklin H, Settleman J, et al. The Q43L mutant of neuregulin 2? is a pan-ErbB receptor antagonist. Biochem J. 2012;443:133-44 pubmed 出版商
Sekiyama A, Gon Y, Terakado M, Takeshita I, Kozu Y, Maruoka S, et al. Glucocorticoids enhance airway epithelial barrier integrity. Int Immunopharmacol. 2012;12:350-7 pubmed 出版商
McWilliam I, Chong Kwan M, Hall D. Inkjet printing for the production of protein microarrays. Methods Mol Biol. 2011;785:345-61 pubmed 出版商
Takahashi Y, Miyamoto T, Shiku H, Ino K, Yasukawa T, Asano R, et al. Electrochemical detection of receptor-mediated endocytosis by scanning electrochemical microscopy. Phys Chem Chem Phys. 2011;13:16569-73 pubmed 出版商
Gon Y, Matsumoto K, Terakado M, Sekiyama A, Maruoka S, Takeshita I, et al. Heregulin activation of ErbB2/ErbB3 signaling potentiates the integrity of airway epithelial barrier. Exp Cell Res. 2011;317:1947-53 pubmed 出版商
Hara T, Miyazaki M, Hakuno F, Takahashi S, Chida K. PKC? promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 mRNA through suppression of JNK/c-Jun signaling under stress conditions. Cell Death Dis. 2011;2:e157 pubmed 出版商
Kormos B, Belso N, Bebes A, Szabad G, Bacsa S, Szell M, et al. In vitro dedifferentiation of melanocytes from adult epidermis. PLoS ONE. 2011;6:e17197 pubmed 出版商
Licitra L, Perrone F, Tamborini E, Bertola L, Ghirelli C, Negri T, et al. Role of EGFR family receptors in proliferation of squamous carcinoma cells induced by wound healing fluids of head and neck cancer patients. Ann Oncol. 2011;22:1886-93 pubmed 出版商
Bertelsen V, Sak M, Breen K, Rødland M, Johannessen L, Traub L, et al. A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner. Traffic. 2011;12:507-20 pubmed 出版商
Mill C, Gettinger K, Riese D. Ligand stimulation of ErbB4 and a constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines. Exp Cell Res. 2011;317:392-404 pubmed 出版商
Tasaki S, Nagasaki M, Kozuka Hata H, Semba K, Gotoh N, Hattori S, et al. Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling. PLoS ONE. 2010;5:e13926 pubmed 出版商
Gupta P, Han S, Holgado Madruga M, Mitra S, Li G, Nitta R, et al. Development of an EGFRvIII specific recombinant antibody. BMC Biotechnol. 2010;10:72 pubmed 出版商
Maiti K, Dinish U, Fu C, Lee J, Soh K, Yun S, et al. Development of biocompatible SERS nanotag with increased stability by chemisorption of reporter molecule for in vivo cancer detection. Biosens Bioelectron. 2010;26:398-403 pubmed 出版商
Tamborini E, Virdis E, Negri T, Orsenigo M, Brich S, Conca E, et al. Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas. Neuro Oncol. 2010;12:776-89 pubmed 出版商
Nencioni A, Cea M, Garuti A, Passalacqua M, Raffaghello L, Soncini D, et al. Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression. PLoS ONE. 2010;5:e9024 pubmed 出版商
Visser Smit G, Place T, Cole S, Clausen K, Vemuganti S, Zhang G, et al. Cbl controls EGFR fate by regulating early endosome fusion. Sci Signal. 2009;2:ra86 pubmed 出版商
Swartling F, Ferletta M, Kastemar M, Weiss W, Westermark B. Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene. 2009;28:3121-31 pubmed 出版商
Takahashi Y, Miyamoto T, Shiku H, Asano R, Yasukawa T, Kumagai I, et al. Electrochemical detection of epidermal growth factor receptors on a single living cell surface by scanning electrochemical microscopy. Anal Chem. 2009;81:2785-90 pubmed 出版商
Perrone F, Da Riva L, Orsenigo M, Losa M, Jocollè G, Millefanti C, et al. PDGFRA, PDGFRB, EGFR, and downstream signaling activation in malignant peripheral nerve sheath tumor. Neuro Oncol. 2009;11:725-36 pubmed 出版商
Rawlins J, Fernandez C, Cozby M, Opperman L. Timing of Egf treatment differentially affects Tgf-beta2 induced cranial suture closure. Exp Biol Med (Maywood). 2008;233:1518-26 pubmed 出版商
Bergin D, Greene C, Sterchi E, Kenna C, Geraghty P, Belaaouaj A, et al. Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway. J Biol Chem. 2008;283:31736-44 pubmed 出版商
Liu Y, Wang B, Wang J, Wan W, Sun R, Zhao Y, et al. Down-regulation of PKCzeta expression inhibits chemotaxis signal transduction in human lung cancer cells. Lung Cancer. 2009;63:210-8 pubmed 出版商
Chastagner P, Israel A, Brou C. AIP4/Itch regulates Notch receptor degradation in the absence of ligand. PLoS ONE. 2008;3:e2735 pubmed 出版商
Quinchia Rios B, Guerrero M, Abozeid S, Bainbridge B, Darveau R, Compton T, et al. Down-regulation of epidermal growth factor receptor-dependent signaling by Porphyromonas gingivalis lipopolysaccharide in life-expanded human gingival fibroblasts. J Periodontal Res. 2008;43:290-304 pubmed 出版商
Szabad G, Kormos B, Pivarcsi A, Szell M, Kis K, Kenderessy Szabo A, et al. Human adult epidermal melanocytes cultured without chemical mitogens express the EGF receptor and respond to EGF. Arch Dermatol Res. 2007;299:191-200 pubmed
Melendez K, Wallen E, Edwards B, Mobarak C, Bear D, Moseley P. Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cells. Cell Stress Chaperones. 2006;11:334-42 pubmed
Rajput A, Koterba A, Kreisberg J, Foster J, Willson J, Brattain M. A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo. Cancer Res. 2007;67:665-73 pubmed
Kim B, Olzmann J, Barsh G, Chin L, Li L. Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking. Mol Biol Cell. 2007;18:1129-42 pubmed
Ning Y, Buranda T, Hudson L. Activated epidermal growth factor receptor induces integrin alpha2 internalization via caveolae/raft-dependent endocytic pathway. J Biol Chem. 2007;282:6380-7 pubmed
Zhang Y, Jiang Y, Geiser V, Zhou J, Jones C. Bovine herpesvirus 1 immediate-early protein (bICP0) interacts with the histone acetyltransferase p300, which stimulates productive infection and gC promoter activity. J Gen Virol. 2006;87:1843-51 pubmed 出版商
McIntire R, Petroff M, Phillips T, Hunt J. In vitro models for studying human uterine and placental macrophages. Methods Mol Med. 2006;122:123-48 pubmed
Sun X, Gemzell Danielsson K, Li H, Ståbi B, Stavreus Evers A. Expression of heparin-binding epidermal growth factor-like growth factor and its receptors in the human fallopian tube and endometrium after treatment with mifepristone. Fertil Steril. 2006;85:171-8 pubmed
Johannessen L, Pedersen N, Pedersen K, Madshus I, Stang E. Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits. Mol Cell Biol. 2006;26:389-401 pubmed
Semino C, Kamm R, Lauffenburger D. Autocrine EGF receptor activation mediates endothelial cell migration and vascular morphogenesis induced by VEGF under interstitial flow. Exp Cell Res. 2006;312:289-98 pubmed
Takai N, Jain A, Kawamata N, Popoviciu L, Said J, Whittaker S, et al. 2C4, a monoclonal antibody against HER2, disrupts the HER kinase signaling pathway and inhibits ovarian carcinoma cell growth. Cancer. 2005;104:2701-8 pubmed
Van Schaeybroeck S, Karaiskou McCaul A, Kelly D, Longley D, Galligan L, Van Cutsem E, et al. Epidermal growth factor receptor activity determines response of colorectal cancer cells to gefitinib alone and in combination with chemotherapy. Clin Cancer Res. 2005;11:7480-9 pubmed
Augoff K, Taboła R, Kula J, Gosk J, Rutowski R. Epidermal growth factor receptor (EGF-R) in Dupuytren's disease. J Hand Surg Br. 2005;30:570-3 pubmed
Amin D, Tuck D, Stern D. Neuregulin-regulated gene expression in mammary carcinoma cells. Exp Cell Res. 2005;309:12-23 pubmed
Wedge S, Kendrew J, Hennequin L, Valentine P, Barry S, Brave S, et al. AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res. 2005;65:4389-400 pubmed
Zhang B, Srirangam A, Potter D, Roman A. HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes. Oncogene. 2005;24:2585-8 pubmed
Spengeman J, Green T, McCubrey J, Bertrand F. Activated EGFR promotes the survival of B-lineage acute leukemia in the absence of stromal cells. Cell Cycle. 2005;4:483-7 pubmed
Aifa S, Aydin J, Nordvall G, Lundstrom I, Svensson S, Hermanson O. A basic peptide within the juxtamembrane region is required for EGF receptor dimerization. Exp Cell Res. 2005;302:108-14 pubmed
Schenk S, Hintermann E, Bilban M, Koshikawa N, Hojilla C, Khokha R, et al. Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution. J Cell Biol. 2003;161:197-209 pubmed
Mariotti A, Kedeshian P, Dans M, Curatola A, Gagnoux Palacios L, Giancotti F. EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. J Cell Biol. 2001;155:447-58 pubmed
产品信息
产品名称 :
表皮生长因子受体(528)抗体
基因名称 :
表皮生长因子受体
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-120
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
表皮生长因子受体
反应物种 :
m, r, h
应用 :
WB (non-reducing), IP, IF, FCM
表位 :
cell surface (h)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。